Rhodamine-triazine based probes for Cu²⁺ in aqueous media and living cells

Zhang, Yan; Zeng, Xi; Mu, Lan; Chen, Yi; Zhang, Jian-Xin; Redshaw, Carl; Wei, Gang

Abstract

The performance of a number of rhodamine-triazine derivatives（probe R1~R4) which utilize rhodamine as the fluorophore with cyanuric chloride as the molecular platform have been evaluated. Spectroscopic analysis revealed that differing structural substitution patterns of the probe resulted in different sensitivity and selectivity for specific metal ions. The probes R1 and R2 were fluorescent/colorimetric probes for Cu²⁺, whilst R3 and R4 were probes for Al³⁺, Cr³⁺ and Fe³⁺. The probe R2 exhibited superior recognition for Cu²⁺ in neutral aqueous medium, and the optical switching behavior of R2 for Cu²⁺ and S²⁻ could be used to construct a molecular logic gate. In addition, fluorescence imaging of probe R2 for Cu²⁺ in living cells was demonstrated.

Citation

Zhang, Y., Zeng, X., Mu, L., Chen, Y., Zhang, J.-X., Redshaw, C., & Wei, G. (2014). Rhodamine-triazine based probes for Cu²⁺ in aqueous media and living cells. Sensors and actuators. B, Chemical, 204(December), 24-30. https://doi.org/10.1016/j.snb.2014.06.125

• Journal Article Type: Review
• Acceptance Date: Jun 28, 2014
• Online Publication Date: Jul 26, 2014
• Publication Date: 2014-12
• Deposit Date: Jun 16, 2015
• Publicly Available Date: Jun 16, 2015
• Journal: Sensors and actuators B : chemical
• Print ISSN: 0925-4005
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 204
• Issue: December
• Pages: 24-30
• DOI: https://doi.org/10.1016/j.snb.2014.06.125
• Keywords: Rhodamine-triazine derivative; Probe; Cu²⁺; Cell imaging
• Public URL: https://hull-repository.worktribe.com/output/375377
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S0925400514008144
• Additional Information: Author's accepted manuscript of article published in: Sensors and actuators B : chemical, 2014, v.204, December at http://www.sciencedirect.com/science/article/pii/S0925400514008144
• Contract Date: Jun 16, 2015