Professor Steve Archibald S.J.Archibald@hull.ac.uk
Professor in Molecular Imaging
Professor Steve Archibald S.J.Archibald@hull.ac.uk
Professor in Molecular Imaging
Dr Louis Allott Louis.Allott@hull.ac.uk
Lecturer in Translational Radiopharmaceutics
The aluminium-[18F]fluoride ([18F]AlF) radiolabelling method combines the favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal-based radiochemistry and has been used to parallel gallium-68 radiopharmaceutical developments. As such, the [18F]AlF method is popular and widely implemented in the development of radiopharmaceuticals for the clinic. In this review, we capture the current status of [18F]AlF-based technology and reflect upon its impact on nuclear medicine, as well as offering our perspective on what the future holds for this unique radiolabelling method.
Archibald, S. J., & Allott, L. (2021). The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules. EJNMMI Radiopharmacy and Chemistry, 6(1), Article 30. https://doi.org/10.1186/s41181-021-00141-0
Journal Article Type | Review |
---|---|
Acceptance Date | Jul 22, 2021 |
Online Publication Date | Aug 26, 2021 |
Publication Date | Dec 1, 2021 |
Deposit Date | Aug 27, 2021 |
Publicly Available Date | Oct 27, 2022 |
Journal | EJNMMI Radiopharmacy and Chemistry |
Electronic ISSN | 2365-421X |
Publisher | SpringerOpen |
Peer Reviewed | Peer Reviewed |
Volume | 6 |
Issue | 1 |
Article Number | 30 |
DOI | https://doi.org/10.1186/s41181-021-00141-0 |
Keywords | Aluminium-[18F]fluoride; [18F]AlF Radiometal; Chelation; Radioconjugate |
Public URL | https://hull-repository.worktribe.com/output/3827689 |
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