Supramolecular Assembly of Tetramethylcucurbit[6]uril and 2-Picolylamine

Fan, Ying; Cen, Ran; Shan, Peihui; Redshaw, Carl; Cong, Hang; Xiao, Xin; Ge, Qingmei

Abstract

The supramolecular assembly of symmetrical tetramethylcucurbit[6]uril (TMeQ[6]) and 2-picolylamine (AMPy) has been investigated via various techniques, including ultraviolet-visible (UV-vis) and nuclear magnetic resonance spectroscopy, isothermal titration calorimetry (ITC), and X-ray crystallography. The results indicated that TMeQ[6] could encapsulate the AMPy guest molecule to form a stable inclusion complex. The rotational restriction of the guest in the cavity of TMeQ[6] resulted in a large negative value of entropy. The X-ray crystal structure of the 1:1 inclusion complex between TMeQ[6] and AMPy revealed that AMPy exists in the elliptical cavity of TMeQ[6].

Citation

Fan, Y., Cen, R., Shan, P., Redshaw, C., Cong, H., Xiao, X., & Ge, Q. (2023). Supramolecular Assembly of Tetramethylcucurbit[6]uril and 2-Picolylamine. ACS Omega, 8(11), 9919–9924. https://doi.org/10.1021/acsomega.2c06989

• Journal Article Type: Article
• Acceptance Date: Feb 23, 2023
• Online Publication Date: Mar 6, 2023
• Publication Date: Mar 21, 2023
• Deposit Date: Mar 8, 2023
• Publicly Available Date: Mar 24, 2023
• Journal: ACS Omega
• Print ISSN: 2470-1343
• Electronic ISSN: 2470-1343
• Publisher: American Chemical Society
• Peer Reviewed: Peer Reviewed
• Volume: 8
• Issue: 11
• Pages: 9919–9924
• DOI: https://doi.org/10.1021/acsomega.2c06989
• Keywords: General Chemical Engineering; General Chemistry
• Public URL: https://hull-repository.worktribe.com/output/4233486