RHOBTB1 (Rho-related BTB domain containing 1)

Cai, Shuo; Rivero-Crespo, Francisco; Schenková, Kristína

Abstract

RhoBTB1 is one of the three members of the RhoBTB family. All RhoBTB proteins are characterized by a GTPase domain followed by a proline-rich region, a tandem of two BTB domains and a C-terminal putative RING finger domain. RHOBTB1 is a putative tumour suppressor gene. Expression of RHOBTB1 has been found decreased in diverse tumors including kidney, breast, stomach and colon cancers and head and neck squamous cell carcinomas. RhoBTB1 is a component of Cullin 3-dependent ubiquitin ligase complexes but its role in tumorigenesis is unknown.

Citation

Cai, S., Rivero-Crespo, F., & Schenková, K. (2016). RHOBTB1 (Rho-related BTB domain containing 1). Atlas of genetics and cytogenetics in oncology and haematology, 20(10), 512-515. https://doi.org/10.4267/2042/66084

• Journal Article Type: Article
• Publication Date: 2016-02
• Deposit Date: Aug 26, 2016
• Publicly Available Date: Aug 26, 2016
• Journal: Atlas of genetics and cytogenetics in oncology and haematology
• Print ISSN: 1768-3262
• Peer Reviewed: Peer Reviewed
• Volume: 20
• Issue: 10
• Pages: 512-515
• DOI: https://doi.org/10.4267/2042/66084
• Keywords: RhoBTB1
• Public URL: https://hull-repository.worktribe.com/output/442641
• Publisher URL: http://atlasgeneticsoncology.org/Genes/RHOBTB1ID42981ch10q22.html
• Additional Information: This is a copy of an open access article published in Atlas of genetics and cytogenetics in oncology and haematology, 2016.