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Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices

Giuntini, F.; Dumoulin, F.; Daly, R.; Ahsen, V.; Scanlan, E. M.; Lavado, A. S. P.; Aylott, J. W.; Rosser, G. A.; Beeby, A.; Boyle, R. W.

Authors

F. Giuntini

F. Dumoulin

R. Daly

V. Ahsen

E. M. Scanlan

A. S. P. Lavado

J. W. Aylott

G. A. Rosser

A. Beeby

Professor Ross Boyle R.W.Boyle@hull.ac.uk
Professor of Biological Chemistry/ Module Coordinator for Biological Macromolecules/ Biological Safety and Genetic Modifications Committee Member



Abstract

Polyacrylamide nanoparticles bearing two orthogonal reactive functionalities were prepared by reverse microemulsion polymerisation. Water-soluble photosensitisers and peptide or carbohydrate moieties were sequentially attached to the new nanospecies by orthogonal conjugations based on copper- catalysed azide-alkyne cycloaddition and isothiocyanate chemistry.

Journal Article Type Article
Publication Date Mar 21, 2012
Journal Nanoscale
Print ISSN 2040-3364
Electronic ISSN 2040-3372
Publisher Royal Society of Chemistry
Peer Reviewed Peer Reviewed
Volume 4
Issue 6
Pages 2034-2045
Institution Citation Giuntini, F., Dumoulin, F., Daly, R., Ahsen, V., Scanlan, E. M., Lavado, A. S. P., …Boyle, R. W. (2012). Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices. Nanoscale, 4(6), 2034-2045. https://doi.org/10.1039/c2nr11947a
DOI https://doi.org/10.1039/c2nr11947a
Keywords Nanoparticles

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