Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices

Giuntini, F.; Dumoulin, F.; Daly, R.; Ahsen, V.; Scanlan, E. M.; Lavado, A. S. P.; Aylott, J. W.; Rosser, G. A.; Beeby, A.; Boyle, R. W.

Abstract

Polyacrylamide nanoparticles bearing two orthogonal reactive functionalities were prepared by reverse microemulsion polymerisation. Water-soluble photosensitisers and peptide or carbohydrate moieties were sequentially attached to the new nanospecies by orthogonal conjugations based on copper- catalysed azide-alkyne cycloaddition and isothiocyanate chemistry.

Citation

Giuntini, F., Dumoulin, F., Daly, R., Ahsen, V., Scanlan, E. M., Lavado, A. S. P., Aylott, J. W., Rosser, G. A., Beeby, A., & Boyle, R. W. (2012). Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices. Nanoscale, 4(6), 2034-2045. https://doi.org/10.1039/c2nr11947a

• Journal Article Type: Article
• Acceptance Date: Jan 18, 2012
• Online Publication Date: Jan 26, 2012
• Publication Date: Mar 21, 2012
• Deposit Date: Nov 13, 2014
• Publicly Available Date: Nov 13, 2014
• Journal: Nanoscale
• Print ISSN: 2040-3364
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 4
• Issue: 6
• Pages: 2034-2045
• DOI: https://doi.org/10.1039/c2nr11947a
• Keywords: Nanoparticles
• Public URL: https://hull-repository.worktribe.com/output/466563
• Contract Date: Nov 13, 2014