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Investigation of the physiology and architecture of Salmonella Enteritidis biofilms under alkaline conditions (2020)
Journal Article
Papakonstantinou, A., & Efthimiou, G. (2020). Investigation of the physiology and architecture of Salmonella Enteritidis biofilms under alkaline conditions. Acta Scientific Microbiology, 3(3), 1-11

Formation of bacterial biοfilms is an important survival strategy in multiple adverse environments. It is often affected by the nature of the attachment surface, the bacterial strain and the surrounding physicochemical conditions. The effect of low p... Read More about Investigation of the physiology and architecture of Salmonella Enteritidis biofilms under alkaline conditions.

Transcriptomic adjustments of Staphylococcus aureus COL (MRSA) forming biofilms under acidic and alkaline conditions (2019)
Journal Article
Efthimiou, G., Tsiamis, G., Typas, M., & Pappas, K. (in press). Transcriptomic adjustments of Staphylococcus aureus COL (MRSA) forming biofilms under acidic and alkaline conditions. Frontiers in Microbiology, https://doi.org/10.3389/fmicb.2019.02393

Methicillin-resistant Staphylococcus aureus (MRSA) strains are important human pathogens and a significant health hazard for hospitals and the food industry. They are resistant to β-lactam antibiotics including methicillin and extremely difficult to... Read More about Transcriptomic adjustments of Staphylococcus aureus COL (MRSA) forming biofilms under acidic and alkaline conditions.

Olive pomace oil can be used as an alternative carbon source for clavulanic acid production by Streptomyces clavuligerus (2019)
Journal Article
Young, T., Li, Y., & Efthimiou, G. (in press). Olive pomace oil can be used as an alternative carbon source for clavulanic acid production by Streptomyces clavuligerus. Waste and biomass valorization, https://doi.org/10.1007/s12649-019-00719-5

Clavulanic acid is an important drug, both medically and economically. It is used to combat bacterial resistance to β-lactam antibiotics and is on the World Health Organisation’s List of Essential Medicines in combination with amoxicillin. An olive o... Read More about Olive pomace oil can be used as an alternative carbon source for clavulanic acid production by Streptomyces clavuligerus.

Effect of Rocket (Eruca sativa) Extract on MRSA Growth and Proteome: Metabolic Adjustments in Plant-Based Media (2017)
Journal Article
Doulgeraki, A. I., Efthimiou, G., Paramithiotis, S., Pappas, K. M., Typas, M. A., & Nychas, G. (2017). Effect of Rocket (Eruca sativa) Extract on MRSA Growth and Proteome: Metabolic Adjustments in Plant-Based Media. Frontiers in Microbiology, 8, https://doi.org/10.3389/fmicb.2017.00782

The emergence of methicillin-resistant Staphylococcus aureus (MRSA) in food has provoked a great concern about the presence of MRSA in associated foodstuff. Although MRSA is often detected in various retailed meat products, it seems that food handler... Read More about Effect of Rocket (Eruca sativa) Extract on MRSA Growth and Proteome: Metabolic Adjustments in Plant-Based Media.

Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2) (2011)
Journal Article
Lewis, R. A., Shahi, S. K., Laing, E., Bucca, G., Efthimiou, G., Bushell, M., & Smith, C. P. (2011). Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2). BMC research notes, 4(1), https://doi.org/10.1186/1756-0500-4-78

Background The present study represents a genome-wide transcriptomic analysis of the response of the model streptomycete Streptomyces coelicolor A3(2) M145 to fermentor culture in Modified Evans Media limited, respectively, for nitrogen, phosphate a... Read More about Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2).

A novel finding that Streptomyces clavuligerus can produce the antibiotic clavulanic acid using olive oil as a sole carbon source (2008)
Journal Article
Efthimiou, G., Thumser, A., & Avignone-Rossa, C. (2008). A novel finding that Streptomyces clavuligerus can produce the antibiotic clavulanic acid using olive oil as a sole carbon source. Journal of applied microbiology, 105(6), 2058-2064. https://doi.org/10.1111/j.1365-2672.2008.03975.x

Aims: This study aims to establish whether commercially available food oils can be used by Streptomyces clavuligerus as sole carbon sources for growth and clavulanic acid production. Methods and results: Batch cultures in bioreactors showed that... Read More about A novel finding that Streptomyces clavuligerus can produce the antibiotic clavulanic acid using olive oil as a sole carbon source.


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