All Outputs (28)

Phaseguide assisted liquid lamination for magnetic particle-based assays (2014)
Journal Article
Phurimsak, C., Yildirim, E., Tarn, M. D., Trietsch, S. J., Hankemeier, T., Pamme, N., & Vulto, P. (2014). Phaseguide assisted liquid lamination for magnetic particle-based assays. Lab on a chip, 14(13), 2334-2343. https://doi.org/10.1039/c4lc00139g

We have developed a magnetic particle-based assay platform in which functionalised magnetic particles are transferred sequentially through laminated volumes of reagents and washing buffers. Lamination of aqueous liquids is achieved via the use of pha... Read More about Phaseguide assisted liquid lamination for magnetic particle-based assays.

On-chip processing of particles and cells via multilaminar flow streams (2013)
Journal Article
Tarn, M. D., Lopez-Martinez, M. J., & Pamme, N. (2014). On-chip processing of particles and cells via multilaminar flow streams. Analytical and Bioanalytical Chemistry, 406(1), 139-161. https://doi.org/10.1007/s00216-013-7363-6

The processing of particles, cells, and droplets for reactions, analyses, labeling, and coating is an important aspect of many microfluidic workflows. However, performing multi-step processes is typically a laborious and timeconsuming endeavor. By ex... Read More about On-chip processing of particles and cells via multilaminar flow streams.

Radiochemistry on chip: towards dose-on-demand synthesis of PET radiopharmaceuticals (2013)
Journal Article
Arima, V., Pascali, G., Lade, O., Kretschmer, H. R., Bernsdorf, I., Hammond, V., Watts, P., De Leonardis, F., Tarn, M. D., Cvetkovic, B. Z., Dittrich, P. S., Vasovic, N., Duane, R., Jaksic, A., Pamme, N., Zacheo, A., Zizzari, A., Marra, L., Perrone, E., Salvadori, P. A., & Rinaldi, R. (2013). Radiochemistry on chip: towards dose-on-demand synthesis of PET radiopharmaceuticals. Lab on a chip, 13(12), 2328-2336. https://doi.org/10.1039/c3lc00055a

We have developed an integrated microfluidic platform for producing 2-[¹⁸F]-fluoro-2-deoxy-D-glucose (¹⁸F-FDG) in continuous flow from a single bolus of radioactive isotope solution, with constant product yields achieved throughout the operation that... Read More about Radiochemistry on chip: towards dose-on-demand synthesis of PET radiopharmaceuticals.

Microfluidic platforms for performing surface-based clinical assays (2011)
Journal Article
Tarn, M. D., & Pamme, N. (2011). Microfluidic platforms for performing surface-based clinical assays. Expert review of molecular diagnostics, 11(7), 711-720. https://doi.org/10.1586/ERM.11.59

The need for fast, specific and portable diagnostic systems for clinical assays has, in recent years, led to an explosion of research into microfluidic chip-based immunoassays towards rapid point-of-care analysis. Such devices exploit small dimension... Read More about Microfluidic platforms for performing surface-based clinical assays.

Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup (2011)
Journal Article
Rodríguez-Villarreal, A. I., Tarn, M. D., Madden, L. A., Lutz, J. B., Greenman, J., Samitier, J., & Pamme, N. (2011). Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup. Lab on a chip, 11(7), 1240-1248. https://doi.org/10.1039/c0lc00464b

The continuous flow focussing and manipulation of particles and cells are important factors in microfluidic applications for performing accurate and reproducible procedures downstream. Many particle focussing methods require complex setups or channel... Read More about Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup.

Continuous flow processes on single magnetic and diamagnetic particles in microfluidic devices (2011)
Thesis
Tarn, M. D. (2011). Continuous flow processes on single magnetic and diamagnetic particles in microfluidic devices. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4211533

Magnetic microparticles have seen increasing interest in (bio)chemical processes in recent years due to their various surface functionalities, high surface-to-volume ratio, small sizes, and ease of manipulation via magnetic fields. However, conventio... Read More about Continuous flow processes on single magnetic and diamagnetic particles in microfluidic devices.

The importance of particle type selection and temperature control for on-chip free-flow magnetophoresis (2009)
Journal Article
Tarn, M. D., Peyman, S. A., Robert, D., Iles, A., Wilhelm, C., & Pamme, N. (2009). The importance of particle type selection and temperature control for on-chip free-flow magnetophoresis. Journal of Magnetism and Magnetic Materials, 321(24), 4115-4122. https://doi.org/10.1016/j.jmmm.2009.08.016

Free-flow magnetophoresis is becoming a popular technique for the separation and manipulation of magnetic particles and materials in microsystems. A wide variety of magnetic particles are commercially available that differ greatly in size and in magn... Read More about The importance of particle type selection and temperature control for on-chip free-flow magnetophoresis.

On-chip diamagnetic repulsion in continuous flow (2009)
Journal Article
Tarn, M. D., Hirota, N., Iles, A., & Pamme, N. (2009). On-chip diamagnetic repulsion in continuous flow. Science and Technology of Advanced Materials, 10(1), 014611 - 014611. https://doi.org/10.1088/1468-6996/10/1/014611

We explore the potential of a microfluidic continuous flow particle separation system based on the repulsion of diamagnetic materials from a high magnetic field. Diamagnetic polystyrene particles in paramagnetic manganese (II) chloride solution were... Read More about On-chip diamagnetic repulsion in continuous flow.