All Outputs (17)

Effects of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People With Coronary Artery Disease: Insights From the HIIT or MISS UK Trial (2024)
Journal Article
Ingle, L., Powell, R., Begg, B., Birkett, S., Nichols, S., Ennis, S., Banerjee, P., Shave, R., & McGregor, G. (2024). Effects of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People With Coronary Artery Disease: Insights From the HIIT or MISS UK Trial. Archives of physical medicine and rehabilitation, https://doi.org/10.1016/j.apmr.2024.03.002

Objective: To compare the characteristics of responders and nonresponders to 8 weeks of exercise training to determine differences in key cardiovascular disease outcomes in people with coronary artery disease (CAD). Design: Secondary analysis of data... Read More about Effects of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People With Coronary Artery Disease: Insights From the HIIT or MISS UK Trial.

Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology (2024)
Journal Article
Nickolay, T., McGregor, G., Powell, R., Begg, B., Birkett, S., Nichols, S., Ennis, S., Banerjee, P., Shave, R., Metcalfe, J., Hoye, A., & Ingle, L. (2024). Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology. PLoS ONE, 19(3 March), Article e0299486. https://doi.org/10.1371/journal.pone.0299486

Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method for evaluating functional capacity, with oxygen pulse (O2Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agreement of iden... Read More about Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology.

The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study (2021)
Journal Article
Nichols, S., Engin, B., Carroll, S., Buckley, J., & Ingle, L. (2021). The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study. Annals of physical and rehabilitation medicine, 64(6), Article 101462. https://doi.org/10.1016/j.rehab.2020.101462

Background: Exercise prescription guidelines for patients undertaking cardiovascular rehabilitation (CR) are based on heart rate training zones and ratings of perceived exertion (RPE). In the UK, guidelines indicate that patients should exercise at a... Read More about The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study.

Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme (2020)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (in press). Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme. PLoS ONE, 15(8), Article e0237197. https://doi.org/10.1371/journal.pone.0237197

BACKGROUND: Recent concerns have cast doubt over the effectiveness of cardiac rehabilitation [CR] programmes for improving cardiorespiratory fitness [CRF] in patients with a history of cardiac disease in the United Kingdom [UK]. We aimed to character... Read More about Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme.

Current insights into exercise-based cardiac rehabilitation in patients with coronary heart disease and chronic heart failure (2020)
Journal Article
Nichols, S., McGregor, G., Breckon, J., & Ingle, L. (in press). Current insights into exercise-based cardiac rehabilitation in patients with coronary heart disease and chronic heart failure. International journal of sports medicine, https://doi.org/10.1055/a-1198-5573

Cardiac rehabilitation is a package of lifestyle secondary prevention strategies designed for patients with coronary heart disease and chronic heart failure. A community-based cardiac rehabilitation programme provides patients with a structured exerc... Read More about Current insights into exercise-based cardiac rehabilitation in patients with coronary heart disease and chronic heart failure.

Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study (2020)
Journal Article
Nichols, S., Taylor, C., Goodman, T., Page, R., Kallvikbacka-Bennett, A., Nation, F., Clark, A. L., Birkett, S. T., Carroll, S., & Ingle, L. (2020). Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study. International journal of cardiology, 305, 25-34. https://doi.org/10.1016/j.ijcard.2020.01.044

© 2020 The Authors Background: Recent evidence suggests that routine exercise-based cardiac rehabilitation (CR) may not lead to a substantial increase in estimated peak oxygen uptake (V̇O2peak). This could reduce the potential benefits of CR and expl... Read More about Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study.

Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence (2019)
Journal Article
Nickolay, T., Nichols, S., Ingle, L., & Hoye, A. (2020). Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence. Current Cardiology Reviews, 16(3), 212-220. https://doi.org/10.2174/1573403X15666190819144336

Coronary collateral vessels supply blood to areas of myocardium at risk after arterial occlusion. Flow through these channels is driven by a pressure gradient between the donor and the occluded artery. Concomitant with increased collateral flow is an... Read More about Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence.

Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective (2019)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (in press). Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective. PLoS ONE, 14(6), Article e0217654. https://doi.org/10.1371/journal.pone.0217654

Abstract:
Background: In recent years, criticism of the percentage range approach for individualised exercise prescription has intensified and we were concerned that sub-optimal exercise dose (especially intensity) may be in part responsible for the... Read More about Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective.

Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription (2019)
Journal Article
Nichols, S., O'Doherty, A., Carroll, S., & Ingle, L. (in press). Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487319856432

Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study (2018)
Journal Article
Nichols, S., Taylor, C., Page, R., Kallvikbacka-Bennett, A., Nation, F., Goodman, T., Clark, A. L., Carroll, S., & Ingle, L. (2018). Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. Sports Medicine - Open, 4(1), https://doi.org/10.1186/s40798-018-0138-z

© 2018, The Author(s). Background: Higher cardiorespiratory fitness (CRF) is associated with lower morbidity and mortality in patients with coronary heart disease (CHD). The mechanisms for this are not fully understood. A more favourable cardiometabo... Read More about Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study.

CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods (2018)
Journal Article
Nichols, S., Nation, F., Goodman, T., Clark, A. L., Carroll, S., & Ingle, L. (2018). CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods. BMJ open, 8(1), e019216. https://doi.org/10.1136/bmjopen-2017-019216

Introduction Cardiac rehabilitation (CR) reduces all-cause and cardiovascular mortality in patients with coronary heart disease (CHD). Much of this improvement has been attributed to the beneficial effects of structured exercise training. However, UK... Read More about CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods.

Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation? (2017)
Journal Article
Nichols, S., Gleadall-Siddall, D. O., Antony, R., Clark, A. L., Cleland, J. G. F., Carroll, S., & Ingle, L. (2018). Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?. Clinical physiology and functional imaging, 38(4), 681-688. https://doi.org/10.1111/cpf.12468

Summary Objective Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method of determining VO2peak. When CPET is unavailable, VO2peak may be estimated from treadmill or cycle ergometer workloads and expressed as estimated metabolic equiva... Read More about Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?.

Validity and reliability of the Apple Watch for measuring heart rate during exercise (2017)
Journal Article
Khushhal, A., Nichols, S., Evans, W., Gleadall-Siddall, D., Page, R., O'Doherty, A. F., Carroll, S., Ingle, L., & Abt, G. (2017). Validity and reliability of the Apple Watch for measuring heart rate during exercise. SMIO / Sports Medicine International Open, 1(6), E206-E211. https://doi.org/10.1055/s-0043-120195

We examined the validity and reliability of the Apple Watch heart rate sensor during and in recovery from exercise. Twenty-one males completed treadmill exercise while wearing two Apple Watches (left and right wrists) and a Polar S810i monitor (crite... Read More about Validity and reliability of the Apple Watch for measuring heart rate during exercise.

High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation (2016)
Journal Article
McGregor, G., Nichols, S., Hamborg, T., Bryning, L., Tudor-Edwards, R., Markland, D., Mercer, J., Birkett, S., Ennis, S., Powell, R., Begg, B., Haykowsky, M. J., Banerjee, P., Ingle, L., Shave, R., & Backx, K. (2016). High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation. BMJ open, 6(11), e012843. https://doi.org/10.1136/bmjopen-2016-012843

Introduction: Current international guidelines for cardiac rehabilitation (CR) advocate moderate-intensity exercise training (MISS, moderate-intensity steady state). This recommendation predates significant advances in medical therapy for coronary he... Read More about High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation.

A clinician's guide to cardiopulmonary exercise testing 2: test interpretation (2015)
Journal Article
Nichols, S., Taylor, C., & Ingle, L. (2015). A clinician's guide to cardiopulmonary exercise testing 2: test interpretation. British journal of hospital medicine, 76(5), 281-289. https://doi.org/10.12968/hmed.2015.76.5.281

Data obtained from cardiopulmonary exercise testing offer additional interpretive power over conventional exercise tolerance testing. When used correctly, these data allow improved clinical decision making in patients with cardiometabolic and respira... Read More about A clinician's guide to cardiopulmonary exercise testing 2: test interpretation.

A clinician's guide to cardiopulmonary exercise testing 1: An introduction (2015)
Journal Article
Nichols, S., Taylor, C., & Ingle, L. (2015). A clinician's guide to cardiopulmonary exercise testing 1: An introduction. British journal of hospital medicine, 76(4), 192-195. https://doi.org/10.12968/hmed.2015.76.4.192

Compared to standard exercise tolerance testing, cardiopulmonary exercise testing is a reliable and powerful tool that can be used for risk stratification, exercise prescription and clinical diagnosis.

Variability of automated carotid intima-media thickness measurements by novice operators (2014)
Journal Article
Nichols, S., Milner, M., Meijer, R., Carroll, S., & Ingle, L. (2016). Variability of automated carotid intima-media thickness measurements by novice operators. Clinical physiology and functional imaging, 36(1), 25-32. https://doi.org/10.1111/cpf.12189

Carotid intima-media thickness (C-IMT) measurements provide a non-invasive assessment of sub-clinical atherosclerosis. The aim of the study was to assess the inter- and intra-observer variability of automated C-IMT measurements undertaken by two novi... Read More about Variability of automated carotid intima-media thickness measurements by novice operators.