All Outputs (147)

Mechanistic in situ and ex situ studies of phase transformations in molecular co-crystals (2020)
Journal Article
Clout, A. E., Buanz, A. B., Pang, Y., Tsui, W. M., Yan, D., Parkinson, G., Prior, T. J., Bučar, D. K., Gaisford, S., & Williams, G. R. (2020). Mechanistic in situ and ex situ studies of phase transformations in molecular co-crystals. Chemistry: a European journal, 26(64), 14645-14653. https://doi.org/10.1002/chem.202002267

Co‐crystallisation is widely explored as a route to improve the physical properties of pharmaceutical active ingredients, but little is known about the fundamental mechanisms of the process. Herein, we apply a hyphenated differential scanning calorim... Read More about Mechanistic in situ and ex situ studies of phase transformations in molecular co-crystals.

Homo‐ and heterodinuclear arene‐linked osmium(II) and ruthenium(II) organometallics: probing the impact of metal variation on reactivity and biological activity (2020)
Journal Article
Wilson, C. S., Prior, T. J., Sandland, J., Savoie, H., Boyle, R. W., & Murray, B. S. (in press). Homo‐ and heterodinuclear arene‐linked osmium(II) and ruthenium(II) organometallics: probing the impact of metal variation on reactivity and biological activity. Chemistry: a European journal, https://doi.org/10.1002/chem.202002052

Dinuclear metallodrugs offer much potential in the development of novel anticancer chemotherapeutics as a result of the distinct interactions possible with biomacromolecular targets and the unique biological activity that can result. Here, we describ... Read More about Homo‐ and heterodinuclear arene‐linked osmium(II) and ruthenium(II) organometallics: probing the impact of metal variation on reactivity and biological activity.

An ethylene cross-bridged pentaazamacrocycle and its Cu2+ complex: constrained ligand topology and excellent kinetic stability (2020)
Journal Article
Shircliff, A. D., Burke, B. P., Davilla, D. J., Burgess, G. E., Okorocha, F. A., Shrestha, A., Allbritton, E. M. A., Nguyen, P. T., Lamar, R. L., Jones, D. G., Gorbet, M. J., Allen, M. B., Eze, J. I., Fernandez, A. T., Ramirez, D., Archibald, S. J., Prior, T. J., Krause, J. A., Oliver, A. G., & Hubin, T. J. (2020). An ethylene cross-bridged pentaazamacrocycle and its Cu2+ complex: constrained ligand topology and excellent kinetic stability. Chemical communications : Chem comm / the Royal Society of Chemistry, 56(54), 7519-7522. https://doi.org/10.1039/d0cc00919a

Rigid and topologically constrained ethylene cross-bridged tetraazamacrocycles have been increasingly utilised for thirty years as they form remarkably stable transition metal complexes for catalysis, biomedical imaging, and inorganic drug molecule a... Read More about An ethylene cross-bridged pentaazamacrocycle and its Cu2+ complex: constrained ligand topology and excellent kinetic stability.

Water-Soluble Rhenium Phosphine Complexes Incorporating the Ph2C(X) Motif (X = O–, NH–): Structural and Cytotoxicity Studies (2020)
Journal Article
Alshamrani, A. F., Prior, T. J., Burke, B. P., Roberts, D. P., Archibald, S. J., Higham, L. J., Stasiuk, G., & Redshaw, C. (2020). Water-Soluble Rhenium Phosphine Complexes Incorporating the Ph2C(X) Motif (X = O–, NH–): Structural and Cytotoxicity Studies. Inorganic chemistry, 59(4), 2367-2378. https://doi.org/10.1021/acs.inorgchem.9b03239

Reaction of [ReOCl3(PPh3)2] or [ReO2I(PPh3)2] with 2,2′-diphenylglycine (dpgH2) in refluxing ethanol afforded the air-stable complex [ReO(dpgH)(dpg)(PPh3)] (1). Treatment of [ReO(OEt)I2(PPh3)2] with 1,2,3-triaza-7-phosphaadamantane (PTA) afforded the... Read More about Water-Soluble Rhenium Phosphine Complexes Incorporating the Ph2C(X) Motif (X = O–, NH–): Structural and Cytotoxicity Studies.

The Application of Reversible Intramolecular Sulfonamide Ligation to Modulate Reactivity in Organometallic Ruthenium(II) Diamine Complexes (2020)
Journal Article
Kemp, S. A., Prior, T. J., Savoie, H., Boyle, R. W., & Murray, B. S. (2020). The Application of Reversible Intramolecular Sulfonamide Ligation to Modulate Reactivity in Organometallic Ruthenium(II) Diamine Complexes. Molecules, 25(2), 244. https://doi.org/10.3390/molecules25020244

Metallation of biomacromolecular species forms the basis for the anticancer activity of many metallodrugs. A major limitation of these compounds is that their reactivity is indiscriminate and can, in principle, occur in healthy tissue as well as canc... Read More about The Application of Reversible Intramolecular Sulfonamide Ligation to Modulate Reactivity in Organometallic Ruthenium(II) Diamine Complexes.

What Causes Carbonates to Form “Shrubby” Morphologies? An Anthropocene Limestone Case Study (2019)
Journal Article
Bastianini, L., Rogerson, M., Mercedes-Martín, R., Prior, T. J., Cesar, E. A., & Mayes, W. M. (2019). What Causes Carbonates to Form “Shrubby” Morphologies? An Anthropocene Limestone Case Study. Frontiers in Earth Science, 7, Article 236. https://doi.org/10.3389/feart.2019.00236

The South Atlantic Aptian “Pre-Salt” shrubby carbonate successions offshore Brazil and Angola are of major interest due to their potential hydrocarbon accumulations. Although the general sedimentology of these deposits is widely recognized to be with... Read More about What Causes Carbonates to Form “Shrubby” Morphologies? An Anthropocene Limestone Case Study.

Crystal structures and Hirshfeld surface analysis of transition-metal complexes of 1,3-azolecarboxylic acids (2019)
Journal Article
Meundaeng, N., Prior, T. J., & Rujiwatra, A. (2019). Crystal structures and Hirshfeld surface analysis of transition-metal complexes of 1,3-azolecarboxylic acids. Acta Crystallographica Section C: Structural Chemistry, 75(9), 1319-1326. https://doi.org/10.1107/S2053229619011525

The crystal structures of five new transition-metal complexes synthesized using thia­zole-2-carb­oxy­lic acid (2-Htza), imidazole-2-carb­oxy­lic acid (2-H2ima) or 1,3-oxazole-4-carb­oxy­lic acid (4-Hoxa), namely di­aqua­bis­(thia­zole-2-carboxyl­ato-... Read More about Crystal structures and Hirshfeld surface analysis of transition-metal complexes of 1,3-azolecarboxylic acids.

Study of the host-guest interaction between: N, N ′-bis[4-(dimethylaminophenyl)methyl]butane-1,4-diamine and the cucuribit [n] urils (n = 6, 7) (2019)
Journal Article
Xiao, Z., Zhou, Y., Xu, W., Prior, T. J., Bian, B., Redshaw, C., Tao, Z., & Xiao, X. (2019). Study of the host-guest interaction between: N, N ′-bis[4-(dimethylaminophenyl)methyl]butane-1,4-diamine and the cucuribit [n] urils (n = 6, 7). New journal of chemistry = Nouveau journal de chimie, 43(37), 14938-14943. https://doi.org/10.1039/c9nj03254a

The interaction between the cucuribit[n]urils (Q[n]), where n = 6 or 7, and the guest N,N/-bis[4-(dimethylaminophenyl)methyl]butane-1,4-diamine (G) has been studied in aqueous solution by 1H NMR spectroscopy, electronic absorption spectroscopy and Is... Read More about Study of the host-guest interaction between: N, N ′-bis[4-(dimethylaminophenyl)methyl]butane-1,4-diamine and the cucuribit [n] urils (n = 6, 7).

Turning on ROP activity in a bimetallic Co/Zn complex supported by a [2+2] Schiff-base macrocycle (2019)
Journal Article
Wang, K., Prior, T. J., & Redshaw, C. (2019). Turning on ROP activity in a bimetallic Co/Zn complex supported by a [2+2] Schiff-base macrocycle. Chemical communications : Chem comm / the Royal Society of Chemistry, 55(75), 11279-11282. https://doi.org/10.1039/c9cc04494a

Homo-dinuclear Co and Zn complexes derived from the macrocycle LH2, {[2-(OH)-5-(R)-C6H2-1,3-(CH)2][CH2CH2(2-C6H4N)2]}2 (R = Me, tBu), revealed near inactivity for the ring opening polymerization (ROP) of the cyclic esters δ-valerolactone (δ-VL) and ϵ... Read More about Turning on ROP activity in a bimetallic Co/Zn complex supported by a [2+2] Schiff-base macrocycle.

The effect of pressure on hydrogen solubility in Zircaloy-4 (2019)
Journal Article
Weekes, H. E., Dye, D., Proctor, J. E., Smith, D., Simionescu, C., Prior, T. J., & Wenman, M. R. (2019). The effect of pressure on hydrogen solubility in Zircaloy-4. Journal of Nuclear Materials, 524, 256-262. https://doi.org/10.1016/j.jnucmat.2019.07.012

The effect of pressure on the room temperature solubility of hydrogen in Zircaloy-4 was examined using synchrotron X-ray diffraction on small ground flake samples in a diamond anvil cell at pressures up to 20.9 GPa. Different combinations of hydrogen... Read More about The effect of pressure on hydrogen solubility in Zircaloy-4.

Synthesis, structure, and cytotoxicity studies of oxidovanadium(IV and V) complexes bearing chelating phenolates (2019)
Journal Article
Miller-Shakesby, D. M., Nigam, S., Brookfield, A., McInnes, E. J., Prior, T. J., Archibald, S. J., & Redshaw, C. (2019). Synthesis, structure, and cytotoxicity studies of oxidovanadium(IV and V) complexes bearing chelating phenolates. Polyhedron, 171, 1-9. https://doi.org/10.1016/j.poly.2019.06.051

The interaction of [VO(acac)2] with 2,6-bis(hydroxymethyl)-4-methylphenol (L1H3) or 6,6/-methylenebis(4-tert-butyl-2-(hydroxymethyl)phenol) (L2H4) in refluxing toluene afforded, following work-up in ethanol, the complexes [VOL1]2 (1) and {[VO(acac)(H... Read More about Synthesis, structure, and cytotoxicity studies of oxidovanadium(IV and V) complexes bearing chelating phenolates.

Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads (2019)
Journal Article
Hubin, T. J., Walker, A. N., Davilla, D. J., Carder Freeman, T. R. N., Epley, B. M., Hasley, T. R., Amoyaw, P. N., Jain, S., Archibald, S. J., Prior, T. J., Krause, J. A., Oliver, A. G., Tekwani, B. L., & Khan, M. O. F. (2019). Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads. Polyhedron, 163, 42-53. https://doi.org/10.1016/j.poly.2019.02.027

© 2019 A total of 44 bis-aryl-monocyclic polyamines, monoaryl-monocyclic polyamines and their transition metal complexes were prepared, chemically characterized, and screened in vitro against the Leishmania donovani promastigotes, axenic amastigotes... Read More about Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads.

Acetate as a model for aspartate-based CXCR4 chemokine receptor binding of cobalt and nickel complexes of cross-bridged tetraazamacrocycles (2019)
Journal Article
Cain, A. N., Carder Freeman, T. N., Roewe, K. D., Cockriel, D. L., Hasley, T. R., Maples, R. D., Allbritton, E. M. A., D'Huys, T., van Loy, T., Burke, B. P., Prior, T. J., Schols, D., Archibald, S. J., & Hubin, T. J. (2019). Acetate as a model for aspartate-based CXCR4 chemokine receptor binding of cobalt and nickel complexes of cross-bridged tetraazamacrocycles. Dalton Transactions : an international journal of inorganic chemistry, 48(8), 2785-2801. https://doi.org/10.1039/c8dt04728f

A number of disease states including WHIM syndrome, HIV infection and cancer have been linked to the chemokine receptor CXCR4. High-affinity CXCR4 antagonist transition metal complexes of configurationally restricted bis-tetraazamacrocyclic ligands h... Read More about Acetate as a model for aspartate-based CXCR4 chemokine receptor binding of cobalt and nickel complexes of cross-bridged tetraazamacrocycles.

Crystal structure of (1,3-thiazole-2-carboxylato-κ N)(1,3-thiazole-2-carboxylic acid-κ N)silver(I) (2019)
Journal Article
Meundaeng, N., Rujiwatra, A., & Prior, T. J. (2019). Crystal structure of (1,3-thiazole-2-carboxylato-κ N)(1,3-thiazole-2-carboxylic acid-κ N)silver(I). Acta Crystallographica Section E: Crystallographic Communications, 75(2), 185-188. https://doi.org/10.1107/S2056989019000124

© Meundaeng et al. 2019. The linear two-coordinate silver (I) complex [Ag(C 4 H 2 NO 2 S)(C 4 H 3 NO 2 S)] or [Ag(2-Htza)(2-tza)] is reported (2-Htza = 1,3-thiazole-2-carboxylic acid). The Ag I ion is coordinated by two heterocyclic N atoms from two... Read More about Crystal structure of (1,3-thiazole-2-carboxylato-κ N)(1,3-thiazole-2-carboxylic acid-κ N)silver(I).

Erratum: Synthesis and structure of the inclusion complex {NDQ[5]K@Q[10](H2O)4}·4NO3·20H2O. (Molecules (2017) 22 (1147) (2019)
Journal Article
Chen, L. X., Kan, J. L., Cong, H., Prior, T. J., Tao, Z., Xiao, X., & Redshaw, C. (2019). Erratum: Synthesis and structure of the inclusion complex {NDQ[5]K@Q[10](H2O)4}·4NO3·20H2O. (Molecules (2017) 22 (1147). Molecules, 24(2), Article 328. https://doi.org/10.3390/molecules24020328

© 2019 by the authors. The authors wish to make the following correction to their paper [1]: We found that in the Authorship section, below the second address, a mistake exists on the published page. The e-mail, which is stated as “juha.kiviluoma@vtt... Read More about Erratum: Synthesis and structure of the inclusion complex {NDQ[5]K@Q[10](H2O)4}·4NO3·20H2O. (Molecules (2017) 22 (1147).

Mono-oxo molybdenum(VI) and tungsten(VI) complexes bearing chelating aryloxides: synthesis, structure and ring opening polymerization of cyclic esters (2018)
Journal Article
Sun, Z., Zhao, Y., Prior, T. J., Elsegood, M. R., Wang, K., Xing, T., & Redshaw, C. (2019). Mono-oxo molybdenum(VI) and tungsten(VI) complexes bearing chelating aryloxides: synthesis, structure and ring opening polymerization of cyclic esters. Dalton Transactions : an international journal of inorganic chemistry, 48(4), 1454-1466. https://doi.org/10.1039/c8dt04566f

The mono-oxo aryloxide complexes [M(O)(L1)2] (M = Mo (1·hexane), W(2·2MeCN)) have been prepared from [Mo(O)(Cl)4] or [W(O)(Ot-Bu)4] and two equivalents of the di-phenol 2,2/-ethylidenebis(4,6-di-tert-butylphenol) L1H2, respectively. Use of in-situ ge... Read More about Mono-oxo molybdenum(VI) and tungsten(VI) complexes bearing chelating aryloxides: synthesis, structure and ring opening polymerization of cyclic esters.

Synthesis of new calixarene-based scandium precursors for medical imaging (2018)
Thesis
Alamri, M. A. R. (2018). Synthesis of new calixarene-based scandium precursors for medical imaging. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4222917

Targeted radionuclide therapy is a new and an effective approach for cancer imaging and therapy complementary to the existing methods. In the last decade, the use of metal complexes in imaging and therapy has gained commonality in most clinical situa... Read More about Synthesis of new calixarene-based scandium precursors for medical imaging.

A study of the interaction between cucurbit[8]uril and alkyl substituted 4-pyrrolidinopyridinium salts (2018)
Journal Article
Xu, W., Kan, J., Yang, B., Prior, T. J., Bian, B., Xiao, X., Tao, Z., & Redshaw, C. (2019). A study of the interaction between cucurbit[8]uril and alkyl substituted 4-pyrrolidinopyridinium salts. Chemistry - An Asian Journal, 14(1), 235-242. https://doi.org/10.1002/asia.201801498

The interaction between cucuribit[8]uril (Q[8]) and a series of 4-pyrrolidinopyridinium salts bearing aliphatic substituents at the pyridinium nitrogen, namely 4-(C4H8N)C5H5NRBr, where R = Et (g1), n-butyl (g2), n-pentyl (g3), n-hexyl (g4), n-octyl (... Read More about A study of the interaction between cucurbit[8]uril and alkyl substituted 4-pyrrolidinopyridinium salts.

Vanadyl sulfates: molecular structure, magnetism and electrochemical activity (2018)
Journal Article
Ignaszak, A., Patterson, N., Radtke, M., Elsegood, M. R., Frese, J. W., Lipman, J. L., Yamato, T., Sanz, S., Brechin, E. K., Prior, T. J., & Redshaw, C. (2018). Vanadyl sulfates: molecular structure, magnetism and electrochemical activity. Dalton Transactions : an international journal of inorganic chemistry, 47(44), 15983-15993. https://doi.org/10.1039/c8dt03626h

Reaction of differing amounts of vanadyl sulfate with p-tert-butylthiacalix[4]areneH4 and base allows access to the vanadyl-sulfate species [NEt4]4[(VO)4(3-OH)4(SO4)4]∙1/2H2O (1), [HNEt3]5[(VO)5(3-O)4(SO4)4]∙4MeCN (2∙4MeCN) and [NEt4]2[(VO)6(O)2(SO... Read More about Vanadyl sulfates: molecular structure, magnetism and electrochemical activity.

Interstitial nitrides revisited - a simple synthesis of MxMo3N (M = Fe, Co, Ni) (2018)
Journal Article
Conway, J. O., & Prior, T. J. (2019). Interstitial nitrides revisited - a simple synthesis of MxMo3N (M = Fe, Co, Ni). Journal of Alloys and Compounds, 774, 69-74. https://doi.org/10.1016/j.jallcom.2018.09.307

The efficient synthesis of polycrystalline filled beta-Mn structured Ni2Mo3N, and the eta-carbides Fe3Mo3N and Co3Mo3N, by a single heating of metal powders at 975 ºC under a hydrogen-nitrogen mixture is reported. Rietveld analysis of high-resolution... Read More about Interstitial nitrides revisited - a simple synthesis of MxMo3N (M = Fe, Co, Ni).