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All Outputs (172)

Optimisation of the preparation phase for orthopaedic surgery: Study protocol for a student-led multimodal prehabilitation feasibility trial (BoneFit) (2025)
Journal Article
Ingle, L., Snook, J., Smith, L., Oliver, B., Bray, J., Wells, L., Moorhouse, J., Dixon, L., Simpson, P., Osman, S., Saxton, J., Rajendran, A., Gopalakrishnan, G., & Symes, T. (2025). Optimisation of the preparation phase for orthopaedic surgery: Study protocol for a student-led multimodal prehabilitation feasibility trial (BoneFit). PLoS ONE, 20(2 February), Article e0314680. https://doi.org/10.1371/journal.pone.0314680

Background Since the Covid-19 pandemic, a surgical backlog for total hip replacement (THR) and total knee replacement (TKR) surgery remains in the United Kingdom. Multimodal prehabilitation pathways (encompassing exercise, nutritional support and psy... Read More about Optimisation of the preparation phase for orthopaedic surgery: Study protocol for a student-led multimodal prehabilitation feasibility trial (BoneFit).

The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing (2024)
Journal Article
Nickolay, T., Ingle, L., Hoye, A., Garrett, A. T., & Gleadall-Siddall, D. O. (2025). The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing. Science & Sports, 40(3), 239-247. https://doi.org/10.1016/j.scispo.2024.10.003

Objectives: This study aimed to assess the relative and absolute reliability (agreement) of various parameters derived from the oxygen pulse ( O˙2Pulse) curve during cardiopulmonary exercise testing (CPET), a tool critical for evaluating cardiopulmon... Read More about The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing.

Effects of resistance training on quality of life, fatigue, physical function, and muscular strength during chemotherapy treatment: a systematic review and meta-analysis (2024)
Journal Article
Metcalfe, J., Orange, S., Madden, L. A., Marshall, P., & Vince, R. V. (2024). Effects of resistance training on quality of life, fatigue, physical function, and muscular strength during chemotherapy treatment: a systematic review and meta-analysis. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 32(9), Article 593. https://doi.org/10.1007/s00520-024-08766-y

Purpose: To systematically review and meta-analyse the efficacy of resistance training on quality of life (QOL), fatigue, physical function, and muscular strength in people diagnosed with cancer undergoing chemotherapy. Methods: Electronic databases... Read More about Effects of resistance training on quality of life, fatigue, physical function, and muscular strength during chemotherapy treatment: a systematic review and meta-analysis.

Validation of field-based running tests to determine maximal aerobic speed in professional rugby league (2024)
Journal Article
Bennett, T., Marshall, P., Barrett, S., Malone, J., Simpson, A., Bray, J., Christopherson, C., Nickolay, T., Metcalfe, J., & Towlson, C. (2024). Validation of field-based running tests to determine maximal aerobic speed in professional rugby league. PLoS ONE, 19(7 July), Article e0306062. https://doi.org/10.1371/journal.pone.0306062

Practitioners place importance on high-speed running (HSR) to monitor training practice and match-play demands, whilst attempting to maximise fitness and minimize the risk of injury occurrence. Practitioners apply various methods to quantify HSR, suc... Read More about Validation of field-based running tests to determine maximal aerobic speed in professional rugby league.

A co-produced teaching experience to promote nursing students’ care and compassion towards mental health service users (2024)
Digital Artefact
Davenport, C., & O'Brien, S. (2024). A co-produced teaching experience to promote nursing students’ care and compassion towards mental health service users. [Website]

This blog describes a teaching session we co-produced and delivered to around 300 second year student nurses. We recently followed it up by publishing an article reflecting on the experience (O’Brien and Davenport, 2024) and highlighting the need for... Read More about A co-produced teaching experience to promote nursing students’ care and compassion towards mental health service users.

Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology (2024)
Journal Article
Nickolay, T., McGregor, G., Powell, R., Begg, B., Birkett, S., Nichols, S., Ennis, S., Banerjee, P., Shave, R., Metcalfe, J., Hoye, A., & Ingle, L. (2024). Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology. PLoS ONE, 19(3 March), Article e0299486. https://doi.org/10.1371/journal.pone.0299486

Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method for evaluating functional capacity, with oxygen pulse (O2Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agreement of iden... Read More about Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology.

Validation of Field-Based Running Tests to Determine Maximal Aerobic Speed in Professional Rugby League: Anonymised data set (2024)
Data
McLaren-Towlson, C., Marshall, P., Simpson, A., Bray, J., & Nickolay, T. (2024). Validation of Field-Based Running Tests to Determine Maximal Aerobic Speed in Professional Rugby League: Anonymised data set. [Data]

Practitioners place importance on high-speed running (HSR) to monitor training practice and match-play demands, whilst attempting to maximise fitness and minimize the risk of injury occurrence. Practitioners apply various methods to quantify HSR, suc... Read More about Validation of Field-Based Running Tests to Determine Maximal Aerobic Speed in Professional Rugby League: Anonymised data set.

Embedding the service user voice to co-produce UK mental health nurse education—A lived experience narrative (2024)
Journal Article
O'Brien, S., & Davenport, C. (2024). Embedding the service user voice to co-produce UK mental health nurse education—A lived experience narrative. Journal of psychiatric and mental health nursing, https://doi.org/10.1111/jpm.13031

What is known on the subject?: Co-production aims to value service user voices and is increasingly used in healthcare. Less is known about how co-production in nursing education is experienced by service users. What the paper adds to existing knowled... Read More about Embedding the service user voice to co-produce UK mental health nurse education—A lived experience narrative.

HVs’ role in providing alcohol advice to women who are pregnant or planning a pregnancy (2024)
Digital Artefact
Walker, J., Smith, L., Hilton, A., Alfred, L., Scholin, L., & Ahankari, A. (2024). HVs’ role in providing alcohol advice to women who are pregnant or planning a pregnancy

Opening paragraph:
Pregnancy is a transformative period in a woman’s life and an important time to lay strong foundations for infant health and wellbeing that can last a lifetime. The health and wellbeing of the mother, her unborn baby and wider fam... Read More about HVs’ role in providing alcohol advice to women who are pregnant or planning a pregnancy.

The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease (2024)
Thesis
Nickolay, T. The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4659878

This thesis investigates the utility of cardiopulmonary exercise testing (CPET) in assessing and managing patients with coronary artery disease (CAD), particularly focusing on the significance of oxygen pulse (O2Pulse) inflections as a marker for myo... Read More about The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease.

Dyadic perspectives on loneliness and social isolation among people with dementia and spousal carers: findings from the IDEAL programme (2023)
Journal Article
Rippon, I., Victor, C. R., Martyr, A., Matthews, F. E., Quinn, C., Rusted, J. M., Jones, R. W., Collins, R., van Horik, J., Pentecost, C., Allan, L., & Clare, L. (in press). Dyadic perspectives on loneliness and social isolation among people with dementia and spousal carers: findings from the IDEAL programme. Aging and Mental Health, 1-9. https://doi.org/10.1080/13607863.2023.2286618

Objectives: This study aims to investigate the impact of self and partner experiences of loneliness and social isolation on life satisfaction in people with dementia and their spousal carers. Methods: We used data from 1042 dementia caregiving dyads... Read More about Dyadic perspectives on loneliness and social isolation among people with dementia and spousal carers: findings from the IDEAL programme.

Automated sulfur-[18F]fluoride exchange radiolabelling of a prostate specific membrane antigen (PSMA) targeted ligand using the GE FASTlab™ cassette-based platform (2023)
Journal Article
Yang, Z., Barnes, C., Domarkas, J., Koch-Paszkowski, J., Wright, J., Amgheib, A., Renard, I., Fu, R., Archibald, S., Aboagye, E. O., & Allott, L. (2023). Automated sulfur-[18F]fluoride exchange radiolabelling of a prostate specific membrane antigen (PSMA) targeted ligand using the GE FASTlab™ cassette-based platform. Reaction Chemistry and Engineering, 8(10), 2403-2407. https://doi.org/10.1039/d3re00307h

Sulfur-[18F]fluoride exchange radiochemistry is a rapid and convenient method for incorporating fluorine-18 into biologically active molecules. We report a fully automated radiolabelling procedure for the synthesis of a [18F]SO3F-bearing prostate spe... Read More about Automated sulfur-[18F]fluoride exchange radiolabelling of a prostate specific membrane antigen (PSMA) targeted ligand using the GE FASTlab™ cassette-based platform.

Promoting an alcohol-free (dry) pregnancy not just for Dry January (2023)
Digital Artefact
Walker, J., Smith, L., Hilton, A., Alfred, L., Scholin, L., & Ahankari, A. (2023). Promoting an alcohol-free (dry) pregnancy not just for Dry January. [website]

Opening paragraph:
Many people make resolutions to take steps towards a healthier lifestyle after the New Year, and ‘Dry January’ is an opportunity to think about cutting down on alcohol consumption.

Making healthy resolutions are also important... Read More about Promoting an alcohol-free (dry) pregnancy not just for Dry January.

Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males (2022)
Journal Article
Shaw, J., Walkington, C., Cole, E., Gleadall-Siddall, D. O., Burke, R., Bray, J., Simpson, A. J., Vince, R. V., & Garrett, A. T. (2022). Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males. PLoS ONE, 17(11), Article e0270093. https://doi.org/10.1371/journal.pone.0270093

Introduction A typical heat acclimation (HA) protocol takes 5–7 d of 60–90 minutes of heat exposure. Identifying the minimum dose of HA required to elicit a heat adapted phenotype could reduce financial constraints on participants and aid in the tape... Read More about Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males.

The Evolution of Scientific Visualisations: A Case Study Approach to Big Data for Varied Audiences (2022)
Book Chapter
Lunn, A. J., Shaw, V., & Winder, I. C. (2022). The Evolution of Scientific Visualisations: A Case Study Approach to Big Data for Varied Audiences. In L. Shapiro, & P. M. Rea (Eds.), Biomedical Visualisation (51-84). Springer. https://doi.org/10.1007/978-3-031-10889-1_3

Visual representations of complex data are a cornerstone of how scientific information is shared. By taking large quantities of data and creating accessible visualisations that show relationships, patterns, outliers, and conclusions, important resear... Read More about The Evolution of Scientific Visualisations: A Case Study Approach to Big Data for Varied Audiences.

Effectiveness of short-term heat acclimation on intermittent sprint performance in the heat with moderately trained males. (2022)
Journal Article
Garrett, A. T., Birkett, M., Gleadall-Siddall, D. O., Burke, R., Bray, J., & Nation, F. (2022). Effectiveness of short-term heat acclimation on intermittent sprint performance in the heat with moderately trained males. Journal of Human Performance in Extreme Environments, 17(1), Article 4. https://doi.org/10.7771/2327-2937.1139

Introduction: Effectiveness of short-term heat acclimation (STHA), over 5-days (permissive dehydration), on intermittent heat stress test (HST) with males.

Methods: Ten, moderately-trained, males (mean [SD]; age 25.6 [8.9] y; stature 180.7 [5.6]... Read More about Effectiveness of short-term heat acclimation on intermittent sprint performance in the heat with moderately trained males..

Making Sense of Evidence: Using Research Training to Promote Organisational Change (2022)
Book Chapter
Wilkinson, K., Boyd, K., Pearson, M., Farrimond, H., Lang, I. A., Fleischer, D., Poole, A., Ralph, N., & Rappert, B. (2022). Making Sense of Evidence: Using Research Training to Promote Organisational Change. In George Mason Police Research Group, & D. Weisburd (Eds.), Translational Criminology in Policing (64-85). Routledge. https://doi.org/10.4324/9781003153009-7

The International Association of Chiefs of Police (IACP) is perhaps the most prominent advocate for such partnerships. Problems confronting public institutions have become more complex in recent years. A number of fields and disciplines have recogniz... Read More about Making Sense of Evidence: Using Research Training to Promote Organisational Change.

Making sense of ‘best start’ : exploring the early experiences of mothers in low-socioeconomic areas (2022)
Thesis
Miles, H. B. Making sense of ‘best start’ : exploring the early experiences of mothers in low-socioeconomic areas. (Thesis). Hull York Medical School, the University of Hull and the University of York. https://hull-repository.worktribe.com/output/4224605

The central concern of this thesis is to better understand how mothers in low- socioeconomic areas, in a city in the north of England experience early mothering. It is particularly interested in broadening understandings of how these lived experience... Read More about Making sense of ‘best start’ : exploring the early experiences of mothers in low-socioeconomic areas.

Practical considerations of dissolved oxygen levels for platelet function under hypoxia (2021)
Journal Article
Kusanto, B., Gordon, A., Naylor-Adamson, L., Atkinson, L., Coupland, C., Booth, Z., Ahmed, Y., Pires, I. M., Stasiuk, G. J., Sturmey, R., Calaminus, S. D., & Arman, M. (2021). Practical considerations of dissolved oxygen levels for platelet function under hypoxia. International Journal of Molecular Sciences, 22(24), Article 13223. https://doi.org/10.3390/ijms222413223

Investigating human platelet function in low-oxygen environments is important in multiple settings, including hypobaric hypoxia (e.g., high altitude), sea level hypoxia-related disease, and thrombus stability. These studies often involve drawing bloo... Read More about Practical considerations of dissolved oxygen levels for platelet function under hypoxia.

Bruton’s tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia (2021)
Journal Article
Naylor-Adamson, L., Chacko, A., Booth, Z., Caserta, S., Jarvis, J., Khan, S., Hart, S. P., Rivero, F., Allsup, D. J., & Arman, M. (2021). Bruton’s tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia. Frontiers in immunology, 12, Article 766272. https://doi.org/10.3389/fimmu.2021.766272

Bacterial infections are a major cause of morbidity and mortality in chronic lymphocytic leukemia (CLL), and infection risk increases in patients treated with the Bruton’s tyrosine kinase (Btk) inhibitor, ibrutinib. Btk and related kinases (like Tec)... Read More about Bruton’s tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia.