All Outputs (209)

Novel liquid crystalline organic semiconducting oligomers incorporating N-heterocyclic carbazole moieties for fluorescent OLEDs (2017)
Journal Article
Hu, G., Kitney, S. P., Kelly, S. M., Harrison, W., & O’Neill, M. (2017). Novel liquid crystalline organic semiconducting oligomers incorporating N-heterocyclic carbazole moieties for fluorescent OLEDs. Liquid crystals, 44(11), 1632-1645. https://doi.org/10.1080/02678292.2017.1306633

A novel class of nematic liquid crystalline organic semiconducting oligomers incorporating N-heterocyclic carbazole moieties has been synthesised using simple and highly efficient reaction pathways. The electroluminescent colour of these novel oligom... Read More about Novel liquid crystalline organic semiconducting oligomers incorporating N-heterocyclic carbazole moieties for fluorescent OLEDs.

NanoSOSG : a nanostructured fluorescent probe for detection of intracellular singlet oxygen (2017)
Journal Article
Ruiz-González, R., Gulías, Ò., Ruiz-González, R., Bresolí-Obach, R., Gulías, Ò., Agut, M., Savoie, H., Boyle, R. W., Nonell, S., & Giuntini, F. (2017). NanoSOSG : a nanostructured fluorescent probe for detection of intracellular singlet oxygen. Angewandte Chemie, 56(11), 2885-2888. https://doi.org/10.1002/anie.201609050

A biocompatible fluorescent nanoprobe for singlet oxygen (¹O₂) detection in biological systems was designed, synthesized, and characterized, that circumvents many of the limitations of the molecular probe Singlet Oxygen Sensor Green® (SOSG). This wid... Read More about NanoSOSG : a nanostructured fluorescent probe for detection of intracellular singlet oxygen.

Quantifying mating success of territorial males and sneakers in a bower-building cichlid fish (2017)
Journal Article
Magalhaes, I. S., Smith, A. M., & Joyce, D. A. (2017). Quantifying mating success of territorial males and sneakers in a bower-building cichlid fish. Scientific reports, 7(1), Article 41128. https://doi.org/10.1038/srep41128

The strategies and traits males evolve to mate with females are incredible in their diversity. Theory on the evolution of secondary sexual characters suggests that evolving any costly trait or strategy will pay off and stabilise in the population if... Read More about Quantifying mating success of territorial males and sneakers in a bower-building cichlid fish.

Development of an optical thermal history coating sensor based on the oxidation of a divalent rare earth ion phosphor (2016)
Journal Article
Yáñez-González, Á., Ruiz-Trejo, E., van Wachem, B., Skinner, S., Beyrau, F., & Heyes, A. (2016). Development of an optical thermal history coating sensor based on the oxidation of a divalent rare earth ion phosphor. Measurement Science and Technology, 27(11), Article 115103. https://doi.org/10.1088/0957-0233/27/11/115103

The measurement of temperatures in gas turbines, boilers, heat exchangers and other components exposed to hot gases is essential to design energy efficient systems and improve maintenance procedures. When on-line measurements, such as those performed... Read More about Development of an optical thermal history coating sensor based on the oxidation of a divalent rare earth ion phosphor.

How to study basement membrane stiffness as a biophysical trigger in prostate cancer and other age-related pathologies or metabolic diseases (2016)
Journal Article
Rodriguez-Teja, M., Breit, C., Clarke, M., Talar, K., Wang, K., Mohammad, M. A., Pickwell, S., Etchandy, G., Stasiuk, G. J., & Sturge, J. (2016). How to study basement membrane stiffness as a biophysical trigger in prostate cancer and other age-related pathologies or metabolic diseases. Journal of visualized experiments : JoVE, 2016(115), https://doi.org/10.3791/54230

Here we describe a protocol that can be used to study the biophysical microenvironment related to increased thickness and stiffness of the basement membrane (BM) during age-related pathologies and metabolic disorders (e.g. cancer, diabetes, microvasc... Read More about How to study basement membrane stiffness as a biophysical trigger in prostate cancer and other age-related pathologies or metabolic diseases.

Duramycin-porphyrin conjugates for targeting of tumour cells using photodynamic therapy (2016)
Journal Article
Broughton, L. J., Giuntini, F., Savoie, H., Bryden, F., Boyle, R. W., Maraveyas, A., & Madden, L. A. (2016). Duramycin-porphyrin conjugates for targeting of tumour cells using photodynamic therapy. Journal of photochemistry and photobiology. B, Biology, 163, 374-384. https://doi.org/10.1016/j.jphotobiol.2016.09.001

Duramycin, through binding with phosphatidylethanolamine (PE), has been shown to be a selective molecular probe for the targeting and imaging of cancer cells. Photodynamic therapy aims to bring about specific cytotoxic damage to tumours through deliv... Read More about Duramycin-porphyrin conjugates for targeting of tumour cells using photodynamic therapy.

Molecular changes in skin pigmented lesions of the coral trout Plectropomus leopardus (2016)
Journal Article
Lerebours, A., Chapman, E. C., Rotchell, J. M., Heupel, M. R., & Sweet, M. J. (2016). Molecular changes in skin pigmented lesions of the coral trout Plectropomus leopardus. Marine environmental research, 120, 130-135. https://doi.org/10.1016/j.marenvres.2016.07.009

© 2016 Elsevier Ltd A high prevalence of skin pigmented lesions of 15% was recently reported in coral trout Plectropomus leopardus, a commercially important marine fish, inhabiting the Great Barrier Reef. Herein, fish were sampled at two offshore sit... Read More about Molecular changes in skin pigmented lesions of the coral trout Plectropomus leopardus.

Composting paper and grass clippings with anaerobically treated palm oil mill effluent (2016)
Journal Article
Zahrim, A. Y., Leong, P. S., Ayisah, S. R., Janaun, J., Chong, K. P., Cooke, F. M., & Haywood, S. (2016). Composting paper and grass clippings with anaerobically treated palm oil mill effluent. International Journal Of Recycling of Organic Waste in Agriculture, 5(3), 221-230. https://doi.org/10.1007/s40093-016-0131-9

Purpose The purpose of this study is to investigate the composting performance of anaerobically treated palm oil mill effluent (AnPOME) mixed with paper and grass clippings. Methods Composting was conducted using a laboratory scale system for 40 days... Read More about Composting paper and grass clippings with anaerobically treated palm oil mill effluent.

Study of pyridine-mediated electrochemical reduction of CO2 to methanol at high CO2 pressure (2016)
Journal Article
Haywood, S. K., Rybchenko, S. I., Touhami, D., & Wadhawan, J. D. (2016). Study of pyridine-mediated electrochemical reduction of CO2 to methanol at high CO2 pressure. ChemSusChem, 9(13), 1660-1669. https://doi.org/10.1002/cssc.201600267

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim The recently proposed highly efficient route of pyridine-catalyzed CO 2 reduction to methanol was explored on platinum electrodes at high CO 2 pressure. At 55 bar (5.5 MPa) of CO 2 , the bulk elec... Read More about Study of pyridine-mediated electrochemical reduction of CO2 to methanol at high CO2 pressure.

Implications of flexible spacer rotational processes on the liquid crystal behavior of 4,5-dihydroisoxazole benzoate dimers (2016)
Journal Article
Tavares, A., Toldo, J. M., Vilela, G. D., Gonçalves, P. F. B., Bechtold, I. H., Kitney, S. P., Kelly, S. M., & Merlo, A. A. (2016). Implications of flexible spacer rotational processes on the liquid crystal behavior of 4,5-dihydroisoxazole benzoate dimers. New journal of chemistry = Nouveau journal de chimie, 40(1), 393-401. https://doi.org/10.1039/c5nj02199e

The synthesis of some novel non-symmetric liquid crystal dimers, {3-[4-(octyloxyphenyl)]-4,5-dihydroisoxazol-5-yl}alkyl 4-(decyloxy)benzoates (5a–d) and 4-{3-[4-(octyloxyphenyl)]-4,5-dihydroisoxazol-5-yl}alkyl 4-{[6-(octyloxy)naphthalen-2-yl]ethynyl}... Read More about Implications of flexible spacer rotational processes on the liquid crystal behavior of 4,5-dihydroisoxazole benzoate dimers.

Mechanisms of growth inhibition of primary prostate epithelial cells following gamma irradiation or photodynamic therapy including senscence, necrosis, and autophagy, but not apoptosis (2015)
Journal Article
Frame, F. M., Savoie, H., Bryden, F., Giuntini, F., Mann, V. M., Simms, M. S., Boyle, R. W., & Maitland, N. J. (2016). Mechanisms of growth inhibition of primary prostate epithelial cells following gamma irradiation or photodynamic therapy including senscence, necrosis, and autophagy, but not apoptosis. Cancer medicine, 5(1), 61-73. https://doi.org/10.1002/cam4.553

In comparison to more differentiated cells, prostate cancer stem-like cells are radioresistant, which could explain radio-recurrent prostate cancer. Improvement of radiotherapeutic efficacy may therefore require combination therapy. We have investiga... Read More about Mechanisms of growth inhibition of primary prostate epithelial cells following gamma irradiation or photodynamic therapy including senscence, necrosis, and autophagy, but not apoptosis.

Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin (2015)
Journal Article
Entract, G. M., Bryden, F., Domarkas, J., Savoie, H., Allott, L., Archibald, S. J., Cawthorne, C., & Boyle, R. W. (2015). Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin. Molecular pharmaceutics, 12(12), 4414-4423. https://doi.org/10.1021/acs.molpharmaceut.5b00606

Synthesis of the first water-soluble porphyrin radiolabeled with fluorine-18 is described: a new molecular theranostic agent which integrates the therapeutic selectivity of photodynamic therapy (PDT) with the imaging efficacy of positron emission tom... Read More about Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin.

Thermographic laser Doppler velocimetry (2015)
Journal Article
Ojo, A. O., Fond, B., Van Wachem, B. G. M., Heyes, A. L., & Beyrau, F. (2015). Thermographic laser Doppler velocimetry. Optics letters, 40(20), 4759-4762. https://doi.org/10.1364/ol.40.004759

We propose a point measurement technique for simultaneous gas temperature and velocity measurement based on thermographic phosphor particles dispersed in the fluid. The flow velocity is determined from the frequency of light scattered by BaMgAl10O17:... Read More about Thermographic laser Doppler velocimetry.

3-(4-Bromophenyl)-5-(4-hydroxyphenyl)isoxazole: a versatile, new molecular building block for side-chain liquid crystal oligomers and polymers (2015)
Journal Article
Vilela, G. D., Fernandes, T. H. M., da Rosa, R. R., Kelly, S. M., Kitney, S. P., & Merlo, A. A. (2016). 3-(4-Bromophenyl)-5-(4-hydroxyphenyl)isoxazole: a versatile, new molecular building block for side-chain liquid crystal oligomers and polymers. Polymer Bulletin, 73(4), 959-973. https://doi.org/10.1007/s00289-015-1529-7

The synthesis and liquid crystalline behaviour of new comb-shaped methacrylate oligomers, derived from a new key intermediate in the synthesis of heterocyclic liquid crystals, i.e., 3-(4-bromophenyl)-5-(4-hydroxyphenyl)isoxazole, are reported. These... Read More about 3-(4-Bromophenyl)-5-(4-hydroxyphenyl)isoxazole: a versatile, new molecular building block for side-chain liquid crystal oligomers and polymers.

Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic (2015)
Journal Article
Maruani, A., Savoie, H., Bryden, F., Caddick, S., Boyle, R., & Chudasama, V. (2015). Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic. Chemical communications : Chem comm / the Royal Society of Chemistry, 51(83), 15304-15307. https://doi.org/10.1039/c5cc06985h

Herein we present a significant step towards next-generation antibody-based photodynamic therapeutics. Site-selective modification of a clinically relevant monoclonal antibody, with a serum-stable linker bearing a strained alkyne, allows for the cont... Read More about Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic.

Büchwald-Hartwig reaction applied to synthesis of new luminescent liquid crystal triarylamines derived from isoxazoles (2015)
Journal Article
Vilela, G. D., Fernandes, T. H. M., Kelly, S. M., & Merlo, A. A. (2015). Büchwald-Hartwig reaction applied to synthesis of new luminescent liquid crystal triarylamines derived from isoxazoles. Molecular crystals and liquid crystals, 612(1), 169-182. https://doi.org/10.1080/15421406.2015.1030982

© 2015 Taylor & Francis Group, LLC. The present work describes the synthesis and characterization of novel series of triarylamines isoxazoles (TAA) addressed to the organic photovoltaic materials. Diarylisoxazoles were synthesized by sequential [3+... Read More about Büchwald-Hartwig reaction applied to synthesis of new luminescent liquid crystal triarylamines derived from isoxazoles.

Effects of low seawater pH on the marine polychaete Platynereis dumerilii (2015)
Journal Article
Wäge, J., Hardege, J. D., Larsson, T. A., Simakov, O., Chapman, E. C., Arendt, D., & Rotchell, J. M. (2015). Effects of low seawater pH on the marine polychaete Platynereis dumerilii. Marine pollution bulletin, 95(1), 166-172. https://doi.org/10.1016/j.marpolbul.2015.04.027

An important priority for any organism is to maintain internal cellular homeostasis including acidbase balance. Yet, the molecular level impacts of changing environmental conditions, such as low pH, remain uncharacterised. Herein, we isolate partial... Read More about Effects of low seawater pH on the marine polychaete Platynereis dumerilii.

PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin (2015)
Journal Article
Bryden, F., Savoie, H., Rosca, E. V., & Boyle, R. W. (2015). PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin. Dalton Transactions : an international journal of inorganic chemistry, 44(11), 4925-4932. https://doi.org/10.1039/c4dt02949f

The development of novel theranostic agents is an important step in the pathway towards personalised medicine, with the combination of diagnostic and therapeutic modalities into a single treatment agent naturally lending itself to the optimisation an... Read More about PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin.

Studies on the sulfation of cellulose α-lipoate and ability of the sulfated product to stabilize colloidal suspensions of gold nanoparticles (2015)
Journal Article
Sarbova, V., Koschella, A., Cheng, F., Kelly, S. M., & Heinze, T. (2015). Studies on the sulfation of cellulose α-lipoate and ability of the sulfated product to stabilize colloidal suspensions of gold nanoparticles. Carbohydrate Polymers, 124, 117-123. https://doi.org/10.1016/j.carbpol.2015.01.080

© 2015 Elsevier Ltd. A versatile method for the synthesis of cellulose α-lipoate with a low degree of substitution (DS) has been developed using N,N-dimethylacetamide (DMA)/LiCl as a solvent and N,N′-carbonyldiimidazole (CDI) as an esterification rea... Read More about Studies on the sulfation of cellulose α-lipoate and ability of the sulfated product to stabilize colloidal suspensions of gold nanoparticles.

Secondary contact seeds phenotypic novelty in cichlid fishes (2015)
Journal Article
Nichols, P., Genner, M. J., van Oosterhout, C., Smith, A., Parsons, P., Sungani, H., Swanstrom, J., & Joyce, D. A. (2015). Secondary contact seeds phenotypic novelty in cichlid fishes. Proceedings of the Royal Society B: Biological Sciences, 282(1798), Article ARTN 20142272. https://doi.org/10.1098/rspb.2014.2272

Theory proposes that genomic admixture between formerly reproductively isolated populations can generate phenotypic novelty for selection to act upon. Secondary contact may therefore be a significant promoter of phenotypic novelty that allows species... Read More about Secondary contact seeds phenotypic novelty in cichlid fishes.