Skip to main content

Research Repository

Advanced Search

All Outputs (205)

Validating a voxel-based finite element model of a human mandible using digital speckle pattern interferometry (2009)
Journal Article
Gröning, F., Liu, J.-S., Fagan, M. J., & O'Higgins, P. (2009). Validating a voxel-based finite element model of a human mandible using digital speckle pattern interferometry. Journal of biomechanics, 42(9), 1224-1229. https://doi.org/10.1016/j.jbiomech.2009.03.025

Finite element analysis is a powerful tool for predicting the mechanical behaviour of complex biological structures like bones, but to be confident in the results of an analysis, the model should be validated against experimental data. In such valida... Read More about Validating a voxel-based finite element model of a human mandible using digital speckle pattern interferometry.

γ-Secretase-dependent cleavage of amyloid precursor protein regulates osteoblast behavior (2009)
Journal Article
McLeod, J., Curtis, N., Lewis, H. D., Good, M. A., Fagan, M. J., & Genever, P. G. (2009). γ-Secretase-dependent cleavage of amyloid precursor protein regulates osteoblast behavior. FASEB Journal, 23(9), 2942-2955. https://doi.org/10.1096/fj.08-121657

gamma-Secretase cleaves amyloid precursor protein (APP) to generate amyloid-beta (A beta) peptides, which aggregate in the brain in Alzheimer's disease (AD). gamma-Secretase also cleaves molecules that regulate osteoblast activity, such as Notch and... Read More about γ-Secretase-dependent cleavage of amyloid precursor protein regulates osteoblast behavior.

Principal component analysis as a tool for analyzing beat-to-beat changes in ECG features: application to ECG-derived respiration (2009)
Journal Article
Langley, P., Bowers, E. J., & Murray, A. (2010). Principal component analysis as a tool for analyzing beat-to-beat changes in ECG features: application to ECG-derived respiration. IEEE transactions on bio-medical engineering / Bio-medical Engineering Group, 57(4), 821-829. https://doi.org/10.1109/TBME.2009.2018297

An algorithm for analyzing changes in ECG morphology based on principal component analysis (PCA) is presented and applied to the derivation of surrogate respiratory signals from single-lead ECGs. The respiratory-induced variability of ECG features, P... Read More about Principal component analysis as a tool for analyzing beat-to-beat changes in ECG features: application to ECG-derived respiration.

Applicability of the kp method to modeling of InAs/GaSb short-period superlattices (2009)
Journal Article
Hong, B. H., Rybchenko, S. I., Itskevich, I. E., Haywood, S. K., Intartaglia, R., Tasco, V., Rainò, G., & De Giorgi, M. (2009). Applicability of the kp method to modeling of InAs/GaSb short-period superlattices. Physical review B: Condensed matter and materials physics, 79(16), 165323-1-165323-4. https://doi.org/10.1103/PhysRevB.79.165323

We investigate the long-standing controversy surrounding modeling of the electronic spectra of InAs/GaSb short-period superlattices (SPSLs). Most commonly, such modeling for semiconductor heterostructures is based on the kp method. However, this meth... Read More about Applicability of the kp method to modeling of InAs/GaSb short-period superlattices.

Type-II InAsxSb1-x/InAs quantum dots for midinfrared applications: Effect of morphology and composition on electronic and optical properties (2009)
Journal Article
Yeap, G. H., Rybchenko, S. I., Itskevich, I. E., & Haywood, S. K. (2009). Type-II InAsxSb1-x/InAs quantum dots for midinfrared applications: Effect of morphology and composition on electronic and optical properties. Physical review B: Condensed matter and materials physics, 79(7), 075305-1-075305-6. https://doi.org/10.1103/physrevb.79.075305

InSb-based self-assembled quantum dots are very promising for the midinfrared (3-5μm) optical range. We have analyzed the effect of geometry and composition on the electronic structure and optical spectra of InAsx Sb1-x /InAs dots. The calculated tra... Read More about Type-II InAsxSb1-x/InAs quantum dots for midinfrared applications: Effect of morphology and composition on electronic and optical properties.

Assessment of the role of sutures in a lizard skull: a computer modelling study (2009)
Journal Article
Moazen, M., Curtis, N., O'Higgins, P., Jones, M. E., Evans, S. E., & Fagan, M. J. (2009). Assessment of the role of sutures in a lizard skull: a computer modelling study. Proceedings of the Royal Society B: Biological Sciences, 276(1654), 39-46. https://doi.org/10.1098/rspb.2008.0863

Sutures form an integral part of the functioning skull, but their role has long been debated among vertebrate morphologists and palaeontologists. Furthermore, the relationship between typical skull sutures, and those involved in cranial kinesis, is p... Read More about Assessment of the role of sutures in a lizard skull: a computer modelling study.

L-band-related interband transition in InSb/GaSb self-assembled quantum dots (2008)
Book Chapter
Rybchenko, S. I., Gupta, R., Itskevich, I. E., & Haywood, S. K. (2008). L-band-related interband transition in InSb/GaSb self-assembled quantum dots. In Springer Proceedings in Physics; Narrow Gap Semiconductors 2007 (81-83). Springer Verlag. https://doi.org/10.1007/978-1-4020-8425-6_20

Effect of lattice-mismatch-induced strain on Γ-, X- and L-conduction-band edges in III-V self-assembled quantum dots has been calculated. The misfit strain is shown to strongly affect the band edges, leading to a possibility of Γ-L and Γ-X crossover.... Read More about L-band-related interband transition in InSb/GaSb self-assembled quantum dots.

Masticatory loading and bone adaptation in the supraorbital torus of developing macaques (2008)
Journal Article
Kupczik, K., Dobson, C. A., Crompton, R. H., Phillips, R., Oxnard, C. E., Fagan, M. J., & O'Higgins, P. (2009). Masticatory loading and bone adaptation in the supraorbital torus of developing macaques. American journal of physical anthropology, 139(2), 193-203. https://doi.org/10.1002/ajpa.20972

Research on the evolution and adaptive significance of primate craniofacial morphologies has focused on adult, fully developed individuals. Here, we investigate the possible relationship between the local stress environment arising from masticatory l... Read More about Masticatory loading and bone adaptation in the supraorbital torus of developing macaques.

Combined finite element and multibody dynamics analysis of biting in aUromastyx hardwickiilizard skull (2008)
Journal Article
Moazen, M., Curtis, N., Evans, S. E., O’Higgins, P., & Fagan, M. J. (2008). Combined finite element and multibody dynamics analysis of biting in aUromastyx hardwickiilizard skull. Journal of anatomy, 213(5), 499-508. https://doi.org/10.1111/j.1469-7580.2008.00980.x

Lizard skulls vary greatly in shape and construction, and radical changes in skull form during evolution have made this an intriguing subject of research. The mechanics of feeding have surely been affected by this change in skull form, but whether th... Read More about Combined finite element and multibody dynamics analysis of biting in aUromastyx hardwickiilizard skull.

A new approach to amino acid racemization in enamel: testing of a less destructive sampling methodology (2008)
Journal Article
Griffin, R. C., Moody, H., Penkman, K. E. H., Fagan, M. J., Curtis, N., & Collins, M. J. (2008). A new approach to amino acid racemization in enamel: testing of a less destructive sampling methodology. Journal of Forensic Sciences, 53(4), 910-916. https://doi.org/10.1111/j.1556-4029.2008.00753.x

Aspartic acid racemization has been found to be an accurate measure of age at death for recent forensic material. This paper examines the practicality of using acid etching of the tooth surface to extract amino acids from the enamel for racemization... Read More about A new approach to amino acid racemization in enamel: testing of a less destructive sampling methodology.

Predicting skull loading: applying multibody dynamics analysis to a macaque skull (2008)
Journal Article
Curtis, N., Kupczik, K., O'Higgins, P., Moazen, M., & Fagan, M. (2008). Predicting skull loading: applying multibody dynamics analysis to a macaque skull. Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 291(5), 491-501. https://doi.org/10.1002/ar.20689

Evaluating stress and strain fields in anatomical structures is a way to test hypotheses that relate specific features of facial and skeletal morphology to mechanical loading. Engineering techniques such as finite element analysis are now commonly us... Read More about Predicting skull loading: applying multibody dynamics analysis to a macaque skull.

Rigid-body analysis of a lizard skull: modelling the skull of Uromastyx hardwickii (2008)
Journal Article
Moazen, M., Curtis, N., Evans, S. E., O'Higgins, P., & Fagan, M. J. (2008). Rigid-body analysis of a lizard skull: modelling the skull of Uromastyx hardwickii. Journal of biomechanics, 41(6), 1274-1280. https://doi.org/10.1016/j.jbiomech.2008.01.012

Lizard skulls vary greatly in their detailed morphology. Theoretical models and practical studies have posited a definite relationship between skull morphology and bite performance, but this can be difficult to demonstrate in vivo. Computer modelling... Read More about Rigid-body analysis of a lizard skull: modelling the skull of Uromastyx hardwickii.

Accurate quantification of the influence of benthic macro- and meio-fauna on the geometric properties of estuarine muds by micro computer tomography (2007)
Journal Article
Mazik, K., Curtis, N., Fagan, M. J., Taft, S., & Elliott, M. (2008). Accurate quantification of the influence of benthic macro- and meio-fauna on the geometric properties of estuarine muds by micro computer tomography. Journal of experimental marine biology and ecology, 354(2), 192-201. https://doi.org/10.1016/j.jembe.2007.11.006

This paper describes the novel application of high resolution micro computer tomography (microCT) to the quantification of the properties of marine biogenic structures. CT scanning has been used to examine sediments in the past but the resolution of... Read More about Accurate quantification of the influence of benthic macro- and meio-fauna on the geometric properties of estuarine muds by micro computer tomography.