All Outputs (669)

The Cough Reflex: The Janus of Respiratory Medicine (2021)
Journal Article
Sykes, D. L., & Morice, A. H. (2021). The Cough Reflex: The Janus of Respiratory Medicine. Frontiers in Physiology, 12, Article 684080. https://doi.org/10.3389/fphys.2021.684080

In clinical practice, we commonly face adversity when encountering dysfunction of the cough reflex. Similar to ancient Roman deity Janus, it often presents with one of two opposing “faces”. Continual aberrant activation of the cough reflex, also know... Read More about The Cough Reflex: The Janus of Respiratory Medicine.

Virtual models of care for people with palliative care needs living in their own home: A systematic meta-review and narrative synthesis (2021)
Journal Article
Disalvo, D., Agar, M., Caplan, G., Murtagh, F. E., Luckett, T., Heneka, N., …Phillips, J. (in press). Virtual models of care for people with palliative care needs living in their own home: A systematic meta-review and narrative synthesis. Palliative medicine, https://doi.org/10.1177/02692163211024451

Background: Access to palliative care in the community enables people to live in their preferred place of care, which is often home. Community palliative care services struggle to provide timely 24-h services to patients and family. This has resulted... Read More about Virtual models of care for people with palliative care needs living in their own home: A systematic meta-review and narrative synthesis.

Rapid realist review of the role of community pharmacy in the public health response to COVID-19 (2021)
Journal Article
Maidment, I., Young, E., MacPhee, M., Booth, A., Zaman, H., Breen, J., …Wong, G. (2021). Rapid realist review of the role of community pharmacy in the public health response to COVID-19. BMJ open, 11(6), Article e050043. https://doi.org/10.1136/bmjopen-2021-050043

Introduction Community pharmacists and their teams have remained accessible to the public providing essential services despite immense pressures during the COVID-19 pandemic. They have successfully expanded the influenza vaccination programme and are... Read More about Rapid realist review of the role of community pharmacy in the public health response to COVID-19.

Current understanding of nonsurgical interventions for refractory differentiated thyroid cancer: a systematic review (2021)
Journal Article
Jones, H., Green, V., England, J., & Greenman, J. (2021). Current understanding of nonsurgical interventions for refractory differentiated thyroid cancer: a systematic review. Future Science OA, 7(7), https://doi.org/10.2144/fsoa-2021-0041

Thyroid cancer incidence and related mortality is increasing year-on-year, and although treatment for early disease with surgery and radioiodine results in a 98% 5-year survival rate, recurrence and treatment refractory disease is evident in an unacc... Read More about Current understanding of nonsurgical interventions for refractory differentiated thyroid cancer: a systematic review.

A systematic exploration of a perinatal wellbeing framework through women's experiences of lumbo-pelvic pain (2021)
Journal Article
Wadephul, F., Glover, L., Jomeen, J., & Hanefeld, N. (2021). A systematic exploration of a perinatal wellbeing framework through women's experiences of lumbo-pelvic pain. Midwifery, 100, Article 103031. https://doi.org/10.1016/j.midw.2021.103031

Background: Women's wellbeing during the perinatal period has received increasing attention in research, policy and practice, but is often poorly defined and conceptualised. We have developed a framework of perinatal wellbeing (PWB) which we will ref... Read More about A systematic exploration of a perinatal wellbeing framework through women's experiences of lumbo-pelvic pain.

Feasibility, acceptability, and efficacy of online supportive care for individuals living with and beyond lung cancer: a systematic review (2021)
Journal Article
Curry, J., Patterson, M., Greenley, S., Pearson, M., & Forbes, C. (in press). Feasibility, acceptability, and efficacy of online supportive care for individuals living with and beyond lung cancer: a systematic review. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, https://doi.org/10.1007/s00520-021-06274-x

Purpose: To examine the evidence of the feasibility, acceptability, and potential efficacy of online supportive care interventions for people living with and beyond lung cancer (LWBLC). Methods: Studies were identified through searches of Medline, EM... Read More about Feasibility, acceptability, and efficacy of online supportive care for individuals living with and beyond lung cancer: a systematic review.

Neurostructural and Neurophysiological Correlates of Multiple Sclerosis Physical Fatigue: Systematic Review and Meta-Analysis of Cross-Sectional Studies (2021)
Journal Article
Ellison, P. M., Goodall, S., Kennedy, N., Dawes, H., Clark, A., Pomeroy, V., …Saxton, J. M. (2022). Neurostructural and Neurophysiological Correlates of Multiple Sclerosis Physical Fatigue: Systematic Review and Meta-Analysis of Cross-Sectional Studies. Neuropsychology Review, 32(3), 506-519. https://doi.org/10.1007/s11065-021-09508-1

Fatigue is one of the most debilitating symptoms for people with multiple sclerosis (PwMS). By consolidating a diverse and conflicting evidence-base, this systematic review and meta-analysis aimed to gain new insights into the neurobiology of MS fati... Read More about Neurostructural and Neurophysiological Correlates of Multiple Sclerosis Physical Fatigue: Systematic Review and Meta-Analysis of Cross-Sectional Studies.

Implantable cardioverter defibrillator devices: when, how and who should discuss deactivation with patients: a systematic literature review (2021)
Journal Article
Freemantle, M., & Murtagh, F. (in press). Implantable cardioverter defibrillator devices: when, how and who should discuss deactivation with patients: a systematic literature review. BMJ supportive & palliative care, Article 2021-002894. https://doi.org/10.1136/bmjspcare-2021-002894

Background: Implantable cardioverter defibrillators (ICDs) are used to treat life-threatening cardiac arrhythmias and prevent sudden cardiac arrest. As recipients age they may develop greater risk of dying as a result of progressive multimorbidity ra... Read More about Implantable cardioverter defibrillator devices: when, how and who should discuss deactivation with patients: a systematic literature review.

Urinary Angiogenin as a Marker for Bladder Cancer: A Meta-Analysis (2021)
Journal Article
Aalami, A. H., Abdeahad, H., Mesgari, M., Sathyapalan, T., & Sahebkar, A. (2021). Urinary Angiogenin as a Marker for Bladder Cancer: A Meta-Analysis. Biomed research international, 2021, Article 5557309. https://doi.org/10.1155/2021/5557309

Aims. Bladder cancer (BCa) is a common cancer in North America and Europe that carries considerable morbidity and mortality. A reliable biomarker for early detection of the bladder is crucial for improving the prognosis of BCA. In this meta-analysis,... Read More about Urinary Angiogenin as a Marker for Bladder Cancer: A Meta-Analysis.

Antioxidative Potentials of Incretin-Based Medications: A Review of Molecular Mechanisms (2021)
Journal Article
Yaribeygi, H., Maleki, M., Sathyapalan, T., Jamialahmadi, T., & Sahebkar, A. (2021). Antioxidative Potentials of Incretin-Based Medications: A Review of Molecular Mechanisms. Oxidative Medicine and Cellular Longevity, 2021, Article 9959320. https://doi.org/10.1155/2021/9959320

Glucagon-like peptide 1 receptor agonists and dipeptidyl-peptidase 4 inhibitors are medications used for managing diabetes, mimicking the metabolic effects of incretin hormones. Recent evidence suggests that these medications have antioxidative poten... Read More about Antioxidative Potentials of Incretin-Based Medications: A Review of Molecular Mechanisms.

The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: a systematic review (2021)
Journal Article
Simms, M., Parker, P., Rigby, A., Whybrow, P., & Twiddy, M. (in press). The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: a systematic review. Ultrasound, https://doi.org/10.1177/1742271X21995212

Background: The use of multiparametric magnetic resonance imaging (mpMRI) within active surveillance of prostate cancer programmes is identified by the UK National Institute for Health and Care Excellence (NICE guideline NG 131 2019) as having a role... Read More about The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: a systematic review.

Scientometric review of artificial intelligence for operations & maintenance of wind turbines: The past, present and future (2021)
Journal Article
Chatterjee, J., & Dethlefs, N. (2021). Scientometric review of artificial intelligence for operations & maintenance of wind turbines: The past, present and future. Renewable & sustainable energy reviews, 144, Article 111051. https://doi.org/10.1016/j.rser.2021.111051

Wind energy has emerged as a highly promising source of renewable energy in recent times. However, wind turbines regularly suffer from operational inconsistencies, leading to significant costs and challenges in operations and maintenance (O&M). Condi... Read More about Scientometric review of artificial intelligence for operations & maintenance of wind turbines: The past, present and future.

Prognostic predictors relevant to end-of-life palliative care in Parkinson's disease and related disorders: A systematic review (2021)
Journal Article
Akbar, U., McQueen, R. B., Bemski, J., Carter, J., Goy, E. R., Kutner, J., …Kluger, B. (2021). Prognostic predictors relevant to end-of-life palliative care in Parkinson's disease and related disorders: A systematic review. Journal of Neurology, Neurosurgery and Psychiatry, 92(6), 629-636. https://doi.org/10.1136/jnnp-2020-323939

Parkinson's disease and related disorders (PDRD) are the second most common neurodegenerative disease and a leading cause of death. However, patients with PDRD receive less end-of-life palliative care (hospice) than other illnesses, including other n... Read More about Prognostic predictors relevant to end-of-life palliative care in Parkinson's disease and related disorders: A systematic review.

The experience of delirium in palliative care settings for patients, family, clinicians and volunteers: A qualitative systematic review and thematic synthesis (2021)
Journal Article
Featherstone, I., Hosie, A., Siddiqi, N., Grassau, P., Bush, S. H., Taylor, J., …Johnson, M. J. (2021). The experience of delirium in palliative care settings for patients, family, clinicians and volunteers: A qualitative systematic review and thematic synthesis. Palliative medicine, 35(6), 988-1004. https://doi.org/10.1177/02692163211006313

Background: Delirium is common in palliative care settings and is distressing for patients, their families and clinicians. To develop effective interventions, we need first to understand current delirium care in this setting. Aim: To understand patie... Read More about The experience of delirium in palliative care settings for patients, family, clinicians and volunteers: A qualitative systematic review and thematic synthesis.

Outcomes and care priorities for older people living with frailty and advanced chronic kidney disease: A multiprofessional scoping review protocol (2021)
Journal Article
Hurst, H., Jones, E., Ormandy, P., Brettle, A., Nixon, A. C., Young, H., …Finnigan, R. (2021). Outcomes and care priorities for older people living with frailty and advanced chronic kidney disease: A multiprofessional scoping review protocol. BMJ open, 11(3), Article e040715. https://doi.org/10.1136/bmjopen-2020-040715

Introduction Reported outcomes for older people with advanced chronic kidney disease (CKD) often focus on survival and mortality and little attention is paid to symptom burden and health-related quality of life. Recognising frailty and providing inte... Read More about Outcomes and care priorities for older people living with frailty and advanced chronic kidney disease: A multiprofessional scoping review protocol.

The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update (2021)
Journal Article
Navashenaq, J. G., Shabgah, A. G., Hedayati-Moghadam, M., Ariaee, N., Mohammadi, H., Hemmatzadeh, M., …Sahebkar, A. (2021). The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update. Life Sciences, 269, https://doi.org/10.1016/j.lfs.2021.119083

© 2021 Rheumatoid arthritis (RA) is an autoimmune disease that generally affects the joints. In the late stages of the disease, it can be associated with several complications. Although the exact etiology of RA is unknown, various studies have been p... Read More about The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update.

Effect of COVID-19 on Mortality of Pregnant and Postpartum Women: A Systematic Review and Meta-Analysis (2021)
Journal Article
Karimi, L., Makvandi, S., Vahedian-Azimi, A., Sathyapalan, T., & Sahebkar, A. (2021). Effect of COVID-19 on Mortality of Pregnant and Postpartum Women: A Systematic Review and Meta-Analysis. Journal of Pregnancy, 2021, 1-33. https://doi.org/10.1155/2021/8870129

Background. Based on what is known at this time, pregnant women are at an increased risk of severe illness from COVID-19 compared to nonpregnant women. Additionally, pregnant women with COVID-19 might have an increased risk of adverse pregnancy outco... Read More about Effect of COVID-19 on Mortality of Pregnant and Postpartum Women: A Systematic Review and Meta-Analysis.

Nurses' experiences of the effects of mindfulness training: A narrative review and qualitative meta-synthesis (2021)
Journal Article
Wu, X., Hayter, M., Lee, A. J., & Zhang, Y. (2021). Nurses' experiences of the effects of mindfulness training: A narrative review and qualitative meta-synthesis. Nurse education today, 100, Article 104830. https://doi.org/10.1016/j.nedt.2021.104830

Objective: To explore nurses' experiences of the effects of undertaking mindfulness training. Design: Qualitative meta-synthesis. Data sources: Qualitative literature from seven scientific databases: Pubmed, Cochran Library, Science Direct, EBSCO, We... Read More about Nurses' experiences of the effects of mindfulness training: A narrative review and qualitative meta-synthesis.

The Nrf2 transcription factor: A multifaceted regulator of the extracellular matrix (2021)
Journal Article
Hiebert, P. (2021). The Nrf2 transcription factor: A multifaceted regulator of the extracellular matrix. Matrix Biology Plus, 10, Article 100057. https://doi.org/10.1016/j.mbplus.2021.100057

The transcription factor nuclear factor-erythroid 2-related factor 2 (Nrf2) is widely recognized as a master regulator of the cellular stress response by facilitating the transcription of cytoprotective genes. As such, the Nrf2 pathway is critical in... Read More about The Nrf2 transcription factor: A multifaceted regulator of the extracellular matrix.

NIR-quantum dots in biomedical imaging and their future (2021)
Journal Article
Gil, H. M., Price, T. W., Chelani, K., Bouillard, J. S. G., Calaminus, S. D., & Stasiuk, G. J. (2021). NIR-quantum dots in biomedical imaging and their future. iScience, 24(3), Article 102189. https://doi.org/10.1016/j.isci.2021.102189

Fluorescence imaging has gathered interest over the recent years for its real-time response and high sensitivity. Developing probes for this modality has proven to be a challenge. Quantum dots (QDs) are colloidal nanoparticles that possess unique opt... Read More about NIR-quantum dots in biomedical imaging and their future.