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Demographic, clinical, and patient-reported outcome data from 2 global, phase 3 trials of chronic cough (2022)
Journal Article
Dicpinigaitis, P. V., Birring, S. S., Blaiss, M., McGarvey, L. P., Morice, A. H., Pavord, I. D., Satia, I., Smith, J. A., La Rosa, C., Li, Q., Nguyen, A. M., Schelfhout, J., Tzontcheva, A., & Muccino, D. (2023). Demographic, clinical, and patient-reported outcome data from 2 global, phase 3 trials of chronic cough. Annals of Allergy, Asthma and Immunology, 130(1), 60-66. https://doi.org/10.1016/j.anai.2022.05.003

Background: The current characterization of patients with refractory or unexplained chronic cough (RCC and UCC, respectively) primarily stems from relatively small clinical studies. Objective: To report the baseline medical history and clinical chara... Read More about Demographic, clinical, and patient-reported outcome data from 2 global, phase 3 trials of chronic cough.

Strengthening Capacity for Prostate Cancer Early Diagnosis in West Africa Amidst the COVID-19 Pandemic: A Realist Approach to Rethinking and Operationalizing the World Health Organization 2017 Guide to Cancer Early Diagnosis (2022)
Journal Article
Ezenwankwo, E. F., Nnate, D. A., Oladoyinbo, C. A., Dogo, H. M., Idowu, A. A., Onyeso, C. P., Ogo, C. N., Ogunsanya, M., Bamidele, O., & Nnaji, C. A. (2022). Strengthening Capacity for Prostate Cancer Early Diagnosis in West Africa Amidst the COVID-19 Pandemic: A Realist Approach to Rethinking and Operationalizing the World Health Organization 2017 Guide to Cancer Early Diagnosis. Annals of Global Health, 88(1), https://doi.org/10.5334/aogh.3519

Two years after SARS-CoV-2 (COVID-19) was declared a global public health emergency, the restoration, at least, to the pre-pandemic level of early diagnostic services for prostate cancer has remained enormously challenging for many health systems, wo... Read More about Strengthening Capacity for Prostate Cancer Early Diagnosis in West Africa Amidst the COVID-19 Pandemic: A Realist Approach to Rethinking and Operationalizing the World Health Organization 2017 Guide to Cancer Early Diagnosis.

Unmarried Adolescents’ Experiences of Using Reproductive and Maternal Health Services in Nigeria and Uganda: A Qualitative Study (2022)
Journal Article
Onukwugha, F., Agaba, P., Hayter, M., & Orton, B. (2022). Unmarried Adolescents’ Experiences of Using Reproductive and Maternal Health Services in Nigeria and Uganda: A Qualitative Study. Social Sciences, 11(5), Article 203. https://doi.org/10.3390/socsci11050203

Adolescents’ access and use of reproductive and maternal health (RMH) services is a critical part of the global strategy for achieving the Sustainable Development Goals (SDGs). However, previous studies have shown that a complex range of factors, inc... Read More about Unmarried Adolescents’ Experiences of Using Reproductive and Maternal Health Services in Nigeria and Uganda: A Qualitative Study.

Persisting breathlessness and activities reduced or ceased: a population study in older men (2022)
Journal Article
Kochovska, S., Currow, D., Chang, S., Johnson, M., Ferreira, D., Morgan, D., Olsson, M., & Ekström, M. (2022). Persisting breathlessness and activities reduced or ceased: a population study in older men. BMJ Open Respiratory Research, 9(1), Article e001168. https://doi.org/10.1136/bmjresp-2021-001168

INTRODUCTION: Breathlessness is debilitating and increases in prevalence with age, with people progressively reducing their everyday activities to 'self-manage' it. This study aimed to evaluate the impact of breathlessness on function in terms of act... Read More about Persisting breathlessness and activities reduced or ceased: a population study in older men.

Etiopathogenesis of Psoriasis from Genetic Perspective: An updated Review (2022)
Journal Article
Babaie, F., Omraninava, M., Gorabi, A. M., Khosrojerdi, A., Aslani, S., Yazdchi, A., Torkamandi, S., Mikaeili, H., Sathyapalan, T., & Sahebkar, A. (2022). Etiopathogenesis of Psoriasis from Genetic Perspective: An updated Review. Current Genomics, 23(3), 163-174. https://doi.org/10.2174/1389202923666220527111037

Psoriasis is an organ-specific autoimmune disease characterized by the aberrant proliferation and differentiation of keratinocytes, leading to skin lesions. Abnormal immune responses mediated by T cells and dendritic cells and increased production of... Read More about Etiopathogenesis of Psoriasis from Genetic Perspective: An updated Review.

A record of microplastic in the marine nearshore waters of South Georgia (2022)
Journal Article
Buckingham, J. W., Manno, C., Waluda, C. M., & Waller, C. L. (2022). A record of microplastic in the marine nearshore waters of South Georgia. Environmental pollution, 306, Article 119379. https://doi.org/10.1016/j.envpol.2022.119379

The polar plastics research community have recommended the spatial coverage of microplastic investigations in Antarctica and the Southern Ocean be increased. Presented here is a baseline estimate of microplastics in the nearshore waters of South Geor... Read More about A record of microplastic in the marine nearshore waters of South Georgia.

Perspectives of Adolescents, Parents, Service Providers, and Teachers on Mobile Phone Use for Sexual Reproductive Health Education (2022)
Journal Article
Ochieng, B. M., Smith, L., Orton, B., Hayter, M., Kaseje, M., Wafula, C. O., Ocholla, P., Onukwugha, F., & Kaseje, D. C. O. (2022). Perspectives of Adolescents, Parents, Service Providers, and Teachers on Mobile Phone Use for Sexual Reproductive Health Education. Social Sciences, 11(5), Article 196. https://doi.org/10.3390/socsci11050196

Mobile health (mHealth) programs offer opportunities to improve the sexual and reproductive health (SRH) of adolescents by providing information. This paper reports the findings of a study carried out in Homabay County, Kenya, to assess stakeholders’... Read More about Perspectives of Adolescents, Parents, Service Providers, and Teachers on Mobile Phone Use for Sexual Reproductive Health Education.

Exploring hypoxic biology to improve radiotherapy outcomes (2022)
Journal Article
Li, C., Wiseman, L., Okoh, E., Lind, M., Roy, R., Beavis, A., & Monteiro dos Santos Pires, I. (2022). Exploring hypoxic biology to improve radiotherapy outcomes. Expert Reviews in Molecular Medicine, 24, Article E21. https://doi.org/10.1017/erm.2022.14

Ionising radiotherapy is a well-established, effective cancer treatment modality, whose efficacy has improved with the application of newer technological modalities. However, patient outcomes are governed and potentially limited by aspects of tumour... Read More about Exploring hypoxic biology to improve radiotherapy outcomes.

Visualizing community networks to recruit South Asian participants for interviews about bowel cancer screening (2022)
Journal Article
Howcutt, S. J., Saini, P., Henshall, C., Brett, J., Watson, E., & Smith, L. A. (2022). Visualizing community networks to recruit South Asian participants for interviews about bowel cancer screening. Journal of Cancer Policy, 32, Article 100333. https://doi.org/10.1016/j.jcpo.2022.100333

Background: South Asians make up the largest ethnic minority group in England and Wales. Yet this group is underrepresented in some programmes to promote health, such as cancer screening. A challenge to addressing such health disparities is the diffi... Read More about Visualizing community networks to recruit South Asian participants for interviews about bowel cancer screening.

Extended-course antibiotic prophylaxis in lower limb amputation: randomized clinical trial (2022)
Journal Article
Souroullas, P., Barnes, R., Carradice, D., Smith, G., Huang, C., & Chetter, I. (2022). Extended-course antibiotic prophylaxis in lower limb amputation: randomized clinical trial. British journal of surgery, 109(5), 426-432. https://doi.org/10.1093/bjs/znac053

BACKGROUND: Lower limb amputation (LLA) is typically described as 'clean surgery', but surgical-site infection (SSI) rates are high and there is significant variation in antibiotic prophylaxis practice. This study aimed to determine whether an extend... Read More about Extended-course antibiotic prophylaxis in lower limb amputation: randomized clinical trial.

Impact of pharmacological interventions on biochemical hyperandrogenemia in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials (2022)
Journal Article
Abdalla, M. A., Shah, N., Deshmukh, H., Sahebkar, A., Östlundh, L., Al-Rifai, R. H., Atkin, S. L., & Sathyapalan, T. (in press). Impact of pharmacological interventions on biochemical hyperandrogenemia in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials. Archives of Gynecology and Obstetrics, https://doi.org/10.1007/s00404-022-06549-6

Context: Polycystic ovary syndrome (PCOS) is a complex endocrine disease that affects women of reproductive age and is characterised by biochemical and clinical androgen excess. Aim: To evaluate the efficacy of pharmacological interventions used to d... Read More about Impact of pharmacological interventions on biochemical hyperandrogenemia in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials.

Severe iatrogenic hypoglycaemia modulates the fibroblast growth factor protein response (2022)
Journal Article
Nandakumar, M., Moin, A. S. M., Ramanjaneya, M., Qaissi, A. A., Sathyapalan, T., Atkin, S. L., & Butler, A. E. (2022). Severe iatrogenic hypoglycaemia modulates the fibroblast growth factor protein response. Diabetes, Obesity and Metabolism, 24(8), 1483-1497. https://doi.org/10.1111/dom.14716

Introduction: There is evidence that fibroblast growth factor (FGF) levels may be implicated in hypoglycaemia, with FGF19 being a potential contributor to insulin-independent pathways driving postprandial hypoglycaemia following bariatric surgery and... Read More about Severe iatrogenic hypoglycaemia modulates the fibroblast growth factor protein response.

Real-world use of once-weekly semaglutide in patients with type 2 diabetes: pooled analysis of data from four SURE studies by baseline characteristic subgroups (2022)
Journal Article
Yale, J. F., Bodholdt, U., Catarig, A. M., Catrina, S., Clark, A., Ekberg, N. R., Erhan, U., Holmes, P., Knudsen, S. T., Liutkus, J., Sathyapalan, T., Schultes, B., & Rudofsky, G. (2022). Real-world use of once-weekly semaglutide in patients with type 2 diabetes: pooled analysis of data from four SURE studies by baseline characteristic subgroups. BMJ Open Diabetes Research and Care, 10(2), Article e002619. https://doi.org/10.1136/bmjdrc-2021-002619

INTRODUCTION: This post hoc pooled analysis of four real-world studies (SURE Canada, Denmark/Sweden, Switzerland and UK) aimed to characterize the use of once-weekly (OW) semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), in patients... Read More about Real-world use of once-weekly semaglutide in patients with type 2 diabetes: pooled analysis of data from four SURE studies by baseline characteristic subgroups.

Anticancer Mechanisms of Berberine: A Good Choice for Glioblasto-ma Multiforme Therapy (2022)
Journal Article
Bibak, B., Shakeri, F., Keshavarzi, Z., Mollazadeh, H., Javid, H., Jalili-Nik, M., Sathyapalan, T., Afshari, A. R., & Sahebkar, A. (2022). Anticancer Mechanisms of Berberine: A Good Choice for Glioblasto-ma Multiforme Therapy. Current medicinal chemistry, 29(26), 4507-4528. https://doi.org/10.2174/0929867329666220224112811

The most typical malignant brain tumor, glioblastoma multiforme (GBM), seems to have a grim outcome, despite the intensive multi-modality interventions. Literature suggests that biologically active phytomolecules may exert anticancer properties by re... Read More about Anticancer Mechanisms of Berberine: A Good Choice for Glioblasto-ma Multiforme Therapy.

Predictors of health facility childbirth among unmarried and married youth in Uganda (2022)
Journal Article
Agaba, P., Magadi, M., & Orton, B. (2022). Predictors of health facility childbirth among unmarried and married youth in Uganda. PLoS ONE, 17(4), Article e0266657. https://doi.org/10.1371/journal.pone.0266657

Background Uganda has a high maternal mortality rate combined with poor use of health facilities at childbirth among youth. Improved use of maternal health services by the youth would help reduce maternal deaths in the country. Predictors of use of h... Read More about Predictors of health facility childbirth among unmarried and married youth in Uganda.

Digital Promotion of Suicide: A Platform-Level Ethical Analysis (2022)
Journal Article
Cohen-Almagor, R., & Lehman-Wilzig, S. (2022). Digital Promotion of Suicide: A Platform-Level Ethical Analysis. Journal of Media Ethics, https://doi.org/10.1080/23736992.2022.2057994

This article utilizes Aristotelian and Kantian philosophies to probe the social responsibilities of internet intermediaries that in one way or another assist and promote suicide. Striking a balance between freedom of expression and social responsibil... Read More about Digital Promotion of Suicide: A Platform-Level Ethical Analysis.

FreeStyle Libre Flash Glucose Monitoring system for people with type 1 diabetes in the UK: a budget impact analysis (2022)
Journal Article
Blissett, R., Blissett, D., Levrat-Guillen, F., Deshmukh, H., Wilmot, E. G., Ryder, R. E., Walton, C., & Sathyapalan, T. (2022). FreeStyle Libre Flash Glucose Monitoring system for people with type 1 diabetes in the UK: a budget impact analysis. BMJ Open Diabetes Research and Care, 10(2), Article e002580. https://doi.org/10.1136/bmjdrc-2021-002580

INTRODUCTION: This study aims to estimate the budget impact of increased uptake of the FreeStyle Libre Flash Glucose Monitoring system in people with type 1 diabetes mellitus (T1DM) in the UK. RESEARCH DESIGN AND METHODS: A budget impact model was de... Read More about FreeStyle Libre Flash Glucose Monitoring system for people with type 1 diabetes in the UK: a budget impact analysis.

Erratum: Correction to: Service Users' Views and Experiences of Alcohol Relapse Prevention Treatment and Adherence: New Role for Pharmacists? (Alcohol and alcoholism (Oxford, Oxfordshire) (2022) 57 5 (602-608)) (2022)
Journal Article
Dhital, R., Coleman, R., Day, E., Drummond, C., Lingford-Hughes, A., Marsden, J., Phillips, T., Sinclair, J., Strang, J., Weinman, J., Whittlesea, C., Widyaratna, K., & Donoghue, K. (2022). Erratum: Correction to: Service Users' Views and Experiences of Alcohol Relapse Prevention Treatment and Adherence: New Role for Pharmacists? (Alcohol and alcoholism (Oxford, Oxfordshire) (2022) 57 5 (602-608)). Alcohol and Alcoholism, 57(5), 642. https://doi.org/10.1093/alcalc/agac016