All Outputs (529)

Association of endocrine active environmental compounds with body mass index and weight loss following bariatric surgery (2020)
Journal Article
Deshmukh, H., Aylward, L. L., Rose, M., Fernandes, A., Sedman, P., Thatcher, N. J., …Sathyapalan, T. (2020). Association of endocrine active environmental compounds with body mass index and weight loss following bariatric surgery. Clinical Endocrinology, 93(3), 280-287. https://doi.org/10.1111/cen.14257

Introduction The objective of this study was to study associations of a wide range of halogenated biphenyls, dibenzo‐p‐dioxins, dibenzofurans, and diphenylethers with body mass index (BMI) and evaluate changes in their concentration following bariat... Read More about Association of endocrine active environmental compounds with body mass index and weight loss following bariatric surgery.

Independent and Interactive Influences of Environmental UVR, Vitamin D Levels, and Folate Variant MTHFD1-rs2236225 on Homocysteine Levels (2020)
Journal Article
Jones, P., Lucock, M., Martin, C., Thota, R., Garg, M., Yates, Z., …Beckett, E. (2020). Independent and Interactive Influences of Environmental UVR, Vitamin D Levels, and Folate Variant MTHFD1-rs2236225 on Homocysteine Levels. Nutrients, 12(5), Article 1455. https://doi.org/10.3390/nu12051455

Psychological concerns of Indian women with breast cancer in different national contexts: A systematic review and mixed-methods synthesis (2020)
Journal Article
Daniel, S., Clark, J., Gnanapragasam, S., Venkateswaran, C., & Johnson, M. J. (in press). Psychological concerns of Indian women with breast cancer in different national contexts: A systematic review and mixed-methods synthesis. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2019-002076

© 2020 Author(s). Background: Breast cancer is becoming the most common cancer among women of Indian origin. However, little is known about the psychological impact of the disease and its treatment among this population. Aim: To improve understanding... Read More about Psychological concerns of Indian women with breast cancer in different national contexts: A systematic review and mixed-methods synthesis.

Relationship between markers of malnutrition and clinical outcomes in older adults with cancer: systematic review, narrative synthesis and meta-analysis (2020)
Journal Article
Bullock, A. F., Greenley, S. L., McKenzie, G. A., Paton, L. W., & Johnson, M. J. (2020). Relationship between markers of malnutrition and clinical outcomes in older adults with cancer: systematic review, narrative synthesis and meta-analysis. European journal of clinical nutrition, 74, 1519–1535. https://doi.org/10.1038/s41430-020-0629-0

© 2020, The Author(s). Malnutrition predicts poorer clinical outcomes for people with cancer. Older adults with cancer are a complex, growing population at high risk of weight-losing conditions. A number of malnutrition screening tools exist, however... Read More about Relationship between markers of malnutrition and clinical outcomes in older adults with cancer: systematic review, narrative synthesis and meta-analysis.

Physical activity and nutrition interventions for older adults with cancer: a systematic review (2020)
Journal Article
Forbes, C. C., Swan, F., Greenley, S. L., Lind, M., & Johnson, M. J. (2020). Physical activity and nutrition interventions for older adults with cancer: a systematic review. Journal of cancer survivorship : research and practice, 14(5), 689-711. https://doi.org/10.1007/s11764-020-00883-x

Purpose: The aim of this review was to summarize the current literature for the effectiveness of activity and nutritional based interventions on health-related quality of life (HRQoL) in older adults living with and beyond cancer (LWBC). Methods: We... Read More about Physical activity and nutrition interventions for older adults with cancer: a systematic review.

Metabolic profile of in vitro derived human embryos is not affected by the mode of fertilization (2020)
Journal Article
Sturmey, R. G., & Leary, C. (2020). Metabolic profile of in vitro derived human embryos is not affected by the mode of fertilization. Molecular Human Reproduction, 26(4), 277-287. https://doi.org/10.1093/molehr/gaaa015

The pattern of metabolism by early embryos in vitro has been linked to a range of phenotypes, including viability. However, the extent to which metabolic function of embryos is modified by specific methods used during ART has yet to be fully describ... Read More about Metabolic profile of in vitro derived human embryos is not affected by the mode of fertilization.

Online Assessment of Applied Anatomy Knowledge: The Effect of Images on Medical Students' Performance (2020)
Journal Article
Sagoo, M. G., Vorstenbosch, M. A., Bazira, P. J., Ellis, H., Kambouri, M., & Owen, C. (2021). Online Assessment of Applied Anatomy Knowledge: The Effect of Images on Medical Students' Performance. Anatomical Sciences Education, 14(3), 342-351. https://doi.org/10.1002/ase.1965

Anatomical examinations have been designed to assess topographical and/or applied knowledge of anatomy with or without the inclusion of visual resources such as cadaveric specimens or images, radiological images, and/or clinical photographs. Multimed... Read More about Online Assessment of Applied Anatomy Knowledge: The Effect of Images on Medical Students' Performance.

Salt Taste Genotype, Dietary Habits and Biomarkers of Health: No Associations in an Elderly Cohort (2020)
Journal Article
Ferraris, C., Turner, A., Kaur, K., Piper, J., Veysey, M., Lucock, M., & Beckett, E. L. (2020). Salt Taste Genotype, Dietary Habits and Biomarkers of Health: No Associations in an Elderly Cohort. Nutrients, 12(4), 1056. https://doi.org/10.3390/nu12041056

A small amount of emerging research has observed variations between individual sensitivity, preference and intake of salt in the presence of single nucleotide polymorphisms (SNP) on the genes encoding salt taste receptors. Sodium intake is a signific... Read More about Salt Taste Genotype, Dietary Habits and Biomarkers of Health: No Associations in an Elderly Cohort.

Maternal pregnancy vitamin D supplementation increases offspring bone formation in response to mechanical loading: Findings from the MAVIDOS trial (2020)
Journal Article
Sujatha Gopal-Kothandapani, J., Rigby, A. S., Harrison, R., Eastell, R., Moon, R. J., Curtis, E. M., …Bishop, N. (2020). Maternal pregnancy vitamin D supplementation increases offspring bone formation in response to mechanical loading: Findings from the MAVIDOS trial. Journal of Musculoskeletal and Neuronal Interactions, 20(1), 4-11

The Maternal Vitamin D Osteoporosis (MAVIDOS) trial reported higher total body bone mineral content in winter-born infants of mothers receiving vitamin D supplementation [1000 IU/day cholecalciferol] compared with placebo from 14 weeks gestation unti... Read More about Maternal pregnancy vitamin D supplementation increases offspring bone formation in response to mechanical loading: Findings from the MAVIDOS trial.

A posture and mobility training package for care home staff: results of a cluster randomised controlled feasibility trial (the PATCH trial) (2020)
Journal Article
Graham, L., Ellwood, A., Hull, K., Fisher, J., Cundill, B., Holland, M., …Forster, A. (2020). A posture and mobility training package for care home staff: results of a cluster randomised controlled feasibility trial (the PATCH trial). Age and ageing, 49(5), 821-828. https://doi.org/10.1093/ageing/afaa046

© The Author(s) 2020. Published by Oxford University Press on behalf of the British Geriatrics Society. BACKGROUND: provision of care for care home residents with complex needs is challenging. Physiotherapy and activity interventions can improve well... Read More about A posture and mobility training package for care home staff: results of a cluster randomised controlled feasibility trial (the PATCH trial).

Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects (2020)
Journal Article
Kahal, H., Halama, A., Aburima, A., Bhagwat, A. M., Butler, A. E., Grauman, J., …Atkin, S. L. (2020). Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects. Scientific reports, 10(1), Article 4750. https://doi.org/10.1038/s41598-020-61531-z

Intensive diabetes control has been associated with increased mortality in type 2 diabetes (T2DM); this has been suggested to be due to increased hypoglycemia. We measured hypoglycemia-induced changes in endothelial parameters, oxidative stress marke... Read More about Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects.

Distribution of variants in multiple vitamin D-related loci (DHCR7/NADSYN1, GC, CYP2R1, CYP11A1, CYP24A1, VDR, RXRα and RXRγ) vary between European, East-Asian and Sub-Saharan African-ancestry populations (2020)
Journal Article
Jones, P., Lucock, M., Chaplin, G., Jablonski, N. G., Veysey, M., Scarlett, C., & Beckett, E. (2020). Distribution of variants in multiple vitamin D-related loci (DHCR7/NADSYN1, GC, CYP2R1, CYP11A1, CYP24A1, VDR, RXRα and RXRγ) vary between European, East-Asian and Sub-Saharan African-ancestry populations. Genes and Nutrition, 15(1), Article 5. https://doi.org/10.1186/s12263-020-00663-3

Background The frequency of vitamin D-associated gene variants appear to reflect changes in long-term ultraviolet B radiation (UVB) environment, indicating interactions exist between the primary determinant of vitamin D status, UVB exposure and gene... Read More about Distribution of variants in multiple vitamin D-related loci (DHCR7/NADSYN1, GC, CYP2R1, CYP11A1, CYP24A1, VDR, RXRα and RXRγ) vary between European, East-Asian and Sub-Saharan African-ancestry populations.

A 12-month continuous and intermittent high-impact exercise intervention and its effects on bone mineral density in early postmenopausal women: A feasibility randomized controlled trial (2020)
Journal Article
Montgomery, G. . J. H., Abt, G., Dobson, C. A., Evans, W. J., Aye, M., & Ditroilo, M. (2020). A 12-month continuous and intermittent high-impact exercise intervention and its effects on bone mineral density in early postmenopausal women: A feasibility randomized controlled trial. Journal of Sports Medicine and Physical Fitness, 60(5), 770-778. https://doi.org/10.23736/S0022-4707.20.10412-2

BACKGROUND: Intermittent mechanical loading generates greater bone adaptations than continuous mechanical loading in rodents but has never been evaluated in humans. This study aimed to evaluate the feasibility of a continuous and intermittent counter... Read More about A 12-month continuous and intermittent high-impact exercise intervention and its effects on bone mineral density in early postmenopausal women: A feasibility randomized controlled trial.

Spatial and pregnancy-related changes in the protein, amino acid, and carbohydrate composition of bovine oviduct fluid (2020)
Journal Article
Rodríguez-Alonso, B., Maillo, V., Acuña, O. S., López-Úbeda, R., Torrecillas, A., Simintiras, C. A., …Rizos, D. (2020). Spatial and pregnancy-related changes in the protein, amino acid, and carbohydrate composition of bovine oviduct fluid. International Journal of Molecular Sciences, 21(5), Article 1681. https://doi.org/10.3390/ijms21051681

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Knowledge of how the biochemical composition of the bovine oviduct is altered due to the oviduct anatomy or the presence of an embryo is lacking. Thus, the aim of this study was to assess the... Read More about Spatial and pregnancy-related changes in the protein, amino acid, and carbohydrate composition of bovine oviduct fluid.

Environmental UVR Levels and Skin Pigmentation Gene Variants Associated with Folate and Homocysteine Levels in an Elderly Cohort (2020)
Journal Article
Jones, P., Lucock, M., Scarlett, C. J., Veysey, M., & Beckett, E. (2020). Environmental UVR Levels and Skin Pigmentation Gene Variants Associated with Folate and Homocysteine Levels in an Elderly Cohort. International Journal of Environmental Research and Public Health, 17(5), Article 1545. https://doi.org/10.3390/ijerph17051545

Ultraviolet radiation (UVR) is a ubiquitous exposure which may contribute to decreased folate levels. Skin pigmentation mediates the biological effect of UVR exposure, but its relationship to folate levels is unexamined. Interactions may exist betwee... Read More about Environmental UVR Levels and Skin Pigmentation Gene Variants Associated with Folate and Homocysteine Levels in an Elderly Cohort.

International palliative care research priorities: A systematic review (2020)
Journal Article
Hasson, F., Nicholson, E., Muldrew, D., Bamidele, O., Payne, S., & McIlfatrick, S. (2020). International palliative care research priorities: A systematic review. BMC Palliative Care, 19(1), Article 16. https://doi.org/10.1186/s12904-020-0520-8

© 2020 The Author(s). Background: There has been increasing evidence and debate on palliative care research priorities and the international research agenda. To date, however, there is a lack of synthesis of this evidence, examining commonalities, di... Read More about International palliative care research priorities: A systematic review.

Development and evaluation of a screening tool to aid the diagnosis of a cluster headache (2020)
Journal Article
Buture, A., Boland, J. W., Dikomitis, L., Huang, C., & Ahmed, F. (2020). Development and evaluation of a screening tool to aid the diagnosis of a cluster headache. Brain Sciences, 10(2), Article 77. https://doi.org/10.3390/brainsci10020077

Cluster headache (CH), a severe primary headache, is often misdiagnosed and mismanaged. The aim of this study was to develop and evaluate a screening tool to aid the diagnosis of CH. We developed a novel 12-item screening tool. This was comprised of... Read More about Development and evaluation of a screening tool to aid the diagnosis of a cluster headache.

A review of therapeutic options for managing the metabolic aspects of polycystic ovary syndrome (2020)
Journal Article
Abdalla, M. A., Deshmukh, H., Atkin, S., & Sathyapalan, T. (2020). A review of therapeutic options for managing the metabolic aspects of polycystic ovary syndrome. Therapeutic Advances in Endocrinology and Metabolism, 11, https://doi.org/10.1177/2042018820938305

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age. Metabolic sequelae associated with PCOS range from insulin resistance to type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Insulin resistanc... Read More about A review of therapeutic options for managing the metabolic aspects of polycystic ovary syndrome.

Randomised, double-blind, multicentre, mixed-methods, dose-escalation feasibility trial of mirtazapine for better treatment of severe breathlessness in advanced lung disease (BETTER-B feasibility) (2020)
Journal Article
Higginson, I., Wilcock, A., Johnson, M. J., Bajwah, S., Lovell, N., Yi, D., …Brown, S. (2020). Randomised, double-blind, multicentre, mixed-methods, dose-escalation feasibility trial of mirtazapine for better treatment of severe breathlessness in advanced lung disease (BETTER-B feasibility). Thorax, 75(2), 176-179. https://doi.org/10.1136/thoraxjnl-2019-213879

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. New treatments are required for severe breathlessness in advanced disease. We conducted a randomised feasibility trial of mirtazapine over 28 days in adults with... Read More about Randomised, double-blind, multicentre, mixed-methods, dose-escalation feasibility trial of mirtazapine for better treatment of severe breathlessness in advanced lung disease (BETTER-B feasibility).

Coronin 1 Is Required for Integrin β2 Translocation in Platelets (2020)
Journal Article
Riley, D. R. J., Khalil, J. S., Pieters, J., Naseem, K. M., & Rivero, F. (in press). Coronin 1 Is Required for Integrin β2 Translocation in Platelets. International Journal of Molecular Sciences, 21(1), Article 356. https://doi.org/10.3390/ijms21010356

Remodeling of the actin cytoskeleton is one of the critical events that allows platelets to undergo morphological and functional changes in response to receptor-mediated signaling cascades. Coronins are a family of evolutionarily conserved proteins i... Read More about Coronin 1 Is Required for Integrin β2 Translocation in Platelets.