All Outputs (1254)

Symmorphosis through dietary regulation: A combinatorial role for proteolysis, autophagy and protein synthesis in normalising muscle metabolism and function of hypertrophic mice after acute starvation (2015)
Journal Article
Collins-Hooper, H., Sartori, R., Giallourou, N., Matsakas, A., Mitchell, R., Mararenkova, H., Flasskamp, H., Macharia, R., Ray, S., Swann, J. R., Sandri, M., & Patel, K. (2015). Symmorphosis through dietary regulation: A combinatorial role for proteolysis, autophagy and protein synthesis in normalising muscle metabolism and function of hypertrophic mice after acute starvation. PLoS ONE, 10(3), e0120524. https://doi.org/10.1371/journal.pone.0120524

Animals are imbued with adaptive mechanisms spanning from the tissue/organ to the cellular scale which insure that processes of homeostasis are preserved in the landscape of size change. However we and others have postulated that the degree of adapta... Read More about Symmorphosis through dietary regulation: A combinatorial role for proteolysis, autophagy and protein synthesis in normalising muscle metabolism and function of hypertrophic mice after acute starvation.

Preliminary observations on the mandibles of palaemonoid shrimp (Crustacea: Decapoda: Caridea: Palaemonoidea) (2015)
Journal Article
Ashelby, C. W., De Grave, S., & Johnson, M. L. (2015). Preliminary observations on the mandibles of palaemonoid shrimp (Crustacea: Decapoda: Caridea: Palaemonoidea). PeerJ, 2015(3), e846. https://doi.org/10.7717/peerj.846

The mandibles of caridean shrimps have been widely studied in the taxonomy and functional biology of the group. Within the Palaemonoidea the mandibles reach a high level of structural diversity reflecting the diverse lifestyles within the superfamily... Read More about Preliminary observations on the mandibles of palaemonoid shrimp (Crustacea: Decapoda: Caridea: Palaemonoidea).

Collateral donor artery physiology and the influence of a chronic total occlusion on fractional flow reserve (2015)
Journal Article
Ladwiniec, A., Cunnington, M. S., Rossington, J., Mather, A. N., Alahmar, A., Oliver, R. M., Nijjer, S. S., Davies, J. E., Thackray, S., Alamgir, F., & Hoye, A. (2015). Collateral donor artery physiology and the influence of a chronic total occlusion on fractional flow reserve. Circulation. Cardiovascular interventions, 8(4), Article UNSP e002219. https://doi.org/10.1161/CIRCINTERVENTIONS.114.002219

Background— The presence of a concomitant chronic total coronary occlusion (CTO) and a large collateral contribution might alter the fractional flow reserve (FFR) of an interrogated vessel, rendering the FFR unreliable at predicting ischemia should t... Read More about Collateral donor artery physiology and the influence of a chronic total occlusion on fractional flow reserve.

NMR study of a bimesogenic liquid crystal with two nematic phases (2015)
Journal Article
Burnell, E. E., Dong, R. Y., Kohlmeier, A., Tamba, M. G., Welch, C., & Mehl, G. H. (2015). NMR study of a bimesogenic liquid crystal with two nematic phases. Molecular crystals and liquid crystals, 610(1), 100-107. https://doi.org/10.1080/15421406.2015.1025211

Recent interest in bimesogenic liquid crystals showing two nematic phases has led us to investigate the nematic mean-field interactions in these nematic phases by using rigid solutes as probes. The nematic potential that is modelled by two independen... Read More about NMR study of a bimesogenic liquid crystal with two nematic phases.

Ice formation on a smooth or rough cold surface due to the impact of a supercooled water droplet (2015)
Journal Article
Elliott, J. W., & Smith, F. T. (2017). Ice formation on a smooth or rough cold surface due to the impact of a supercooled water droplet. Journal of engineering mathematics, 102(1), 35-64. https://doi.org/10.1007/s10665-015-9784-z

Ice accretion is considered in the impact of a supercooled water droplet on a smooth or rough solid surface, the roughness accounting for earlier icing. In this theoretical investigation the emphasis and novelty lie in the full nonlinear interplay of... Read More about Ice formation on a smooth or rough cold surface due to the impact of a supercooled water droplet.

The IGIMF and other IMFs in dSphs: the case of Sagittarius (2015)
Journal Article
Vincenzo, F., Matteucci, F., Recchi, S., Calura, F., McWilliam, A., & A. Lanfranchi, G. (2015). The IGIMF and other IMFs in dSphs: the case of Sagittarius. Monthly notices of the Royal Astronomical Society, 449(2), 1327–1339. https://doi.org/10.1093/mnras/stv357

We have studied the effects of various initial mass functions (IMFs) on the chemical evolution of the Sagittarius dwarf galaxy (Sgr). In particular, we tested the effects of the integrated galactic initial mass function (IGIMF) on various predicted a... Read More about The IGIMF and other IMFs in dSphs: the case of Sagittarius.

Clinical and molecular characterization of a cardiac ryanodine receptor founder mutation causing catecholaminergic polymorphic ventricular tachycardia (2015)
Journal Article
Wangüemert, F., Bosch Calero, C., Pérez, C., Campuzano, O., Beltran-Alvarez, P., Scornik, F. S., Iglesias, A., Berne, P., Allegue, C., Ruiz Hernandez, P. M., Brugada, J., Pérez, G. J., & Brugada, R. (2015). Clinical and molecular characterization of a cardiac ryanodine receptor founder mutation causing catecholaminergic polymorphic ventricular tachycardia. Heart rhythm : the official journal of the Heart Rhythm Society, 12(7), 1636-1643. https://doi.org/10.1016/j.hrthm.2015.03.033

Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a difficult-to-diagnose cause of sudden cardiac death (SCD). We identified a family of 1400 individuals with multiple cases of CPVT, including 36 SCDs during youth. Objectives... Read More about Clinical and molecular characterization of a cardiac ryanodine receptor founder mutation causing catecholaminergic polymorphic ventricular tachycardia.

Imagined relational capital: An analytical tool in considering small tourism firms' sociality (2015)
Journal Article
Saxena, G. (2015). Imagined relational capital: An analytical tool in considering small tourism firms' sociality. Tourism Management, 49, 109-118. https://doi.org/10.1016/j.tourman.2015.03.002

In this paper I introduce the notion of imagined relational capital (IRC) to examine the sociality of small tourism firms operating in coastal towns of Scarborough, Bridlington and Whitby in Yorkshire. Drawing upon the work of Deleuze and Guattari, I... Read More about Imagined relational capital: An analytical tool in considering small tourism firms' sociality.

PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin (2015)
Journal Article
Bryden, F., Savoie, H., Rosca, E. V., & Boyle, R. W. (2015). PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin. Dalton Transactions : an international journal of inorganic chemistry, 44(11), 4925-4932. https://doi.org/10.1039/c4dt02949f

The development of novel theranostic agents is an important step in the pathway towards personalised medicine, with the combination of diagnostic and therapeutic modalities into a single treatment agent naturally lending itself to the optimisation an... Read More about PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin.

Audit committees, non-audit services, and auditor reporting decisions prior to failure (2015)
Journal Article
Wu, C., Hsu, H. H., & Haslam, J. (2016). Audit committees, non-audit services, and auditor reporting decisions prior to failure. The British accounting review, 48(2), 240-256. https://doi.org/10.1016/j.bar.2015.03.001

This study investigates the associations between audit committee characteristics and the likelihood of auditors’ going-concern decisions among UK failed firms. Specifically, we examine whether the threat posed by auditor-provided non-audit services (... Read More about Audit committees, non-audit services, and auditor reporting decisions prior to failure.

The first legal mortgagor: a consumer without adequate protection? (2015)
Journal Article
Whitehouse, L. (2015). The first legal mortgagor: a consumer without adequate protection?. Journal of consumer policy, 38(2), 161-180. https://doi.org/10.1007/s10603-015-9284-6

This article contends that the UK government’s attempt to create a well-functioning consumer credit market will be undermined if it fails to reform the private law framework relating to the first legal mortgage. Such agreements are governed by two di... Read More about The first legal mortgagor: a consumer without adequate protection?.

Shadows along the spiritual pathway (2015)
Journal Article
Humphrey, C. (2015). Shadows along the spiritual pathway. Journal of religion and health, 54(6), 2376-2388. https://doi.org/10.1007/s10943-015-0037-2

Contemporary spirituality discourses tend to assume that a canopy of light and love overarches all spiritual pathways. Unfortunately, the dark side of humanity cannot be spirited away so easily, and aberrations of personal spiritual development, inte... Read More about Shadows along the spiritual pathway.

The economic benefits of increasing kangaroo skin-to-skin care and breastfeeding in neonatal units: Analysis of a pragmatic intervention in clinical practice (2015)
Journal Article
Lowson, K., Offer, C., Watson, J., McGuire, B., & Renfrew, M. J. (2015). The economic benefits of increasing kangaroo skin-to-skin care and breastfeeding in neonatal units: Analysis of a pragmatic intervention in clinical practice. International Breastfeeding Journal, 10(1), Article 11. https://doi.org/10.1186/s13006-015-0035-8

© Lowson et al.; licensee BioMed Central. Background: A number of significant recent research studies have used techniques of economic modelling to demonstrate the potential benefits of increasing breastfeeding rates in the UK overall, and specifical... Read More about The economic benefits of increasing kangaroo skin-to-skin care and breastfeeding in neonatal units: Analysis of a pragmatic intervention in clinical practice.

The Impact of Chronic Cough: A Cross-Sectional European Survey (2015)
Journal Article
Chamberlain, S. A., Garrod, R., Douiri, A., Masefield, S., Powell, P., Bücher, C., Pandyan, A., Morice, A. H., & Birring, S. S. (2015). The Impact of Chronic Cough: A Cross-Sectional European Survey. Lung, 193(3), 401-408. https://doi.org/10.1007/s00408-015-9701-2

© 2015, Springer Science+Business Media New York. Purpose: Studies that investigate the impact of chronic cough have largely focused on patients attending secondary care. Our aim was to investigate the opinions of the wider general population across... Read More about The Impact of Chronic Cough: A Cross-Sectional European Survey.

Age-related deviation of gait from normality in alkaptonuria (2015)
Journal Article
Barton, G. J., King, S. L., Robinson, M. A., Hawken, M. B., & Ranganath, L. R. (2015). Age-related deviation of gait from normality in alkaptonuria. JIMD Reports, 24, 39-44. https://doi.org/10.1007/8904_2015_431

Alkaptonuria is a rare metabolic disease leading to systemic changes including early and severe arthropathy which affects mobility. For unknown reasons, the onset of degenerative changes is delayed to around 30 years of age when both objective and su... Read More about Age-related deviation of gait from normality in alkaptonuria.

Prostate cancer cells stimulated by calcium-mediated activation of protein kinase C undergo a refractory period before re-releasing calcium-bearing microvesicles (2015)
Journal Article
Stratton, D., Moore, C., Zheng, L., Lange, S., & Inal, J. (2015). Prostate cancer cells stimulated by calcium-mediated activation of protein kinase C undergo a refractory period before re-releasing calcium-bearing microvesicles. Biochemical and biophysical research communications, 460(3), 511-517. https://doi.org/10.1016/j.bbrc.2015.03.061

© 2015 Elsevier Inc.All rights reserved. MVs are released in response to several stress agents, in an attempt to prevent continued cellular damage. After an initial stimulus of prostate cancer cells with sublytic C5b-9 and activation of MV release th... Read More about Prostate cancer cells stimulated by calcium-mediated activation of protein kinase C undergo a refractory period before re-releasing calcium-bearing microvesicles.

Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design (2015)
Journal Article
Campbell, R. T., Jackson, C. E., Wright, A., Gardner, R. S., Ford, I., Davidson, P. M., Denvir, M. A., Hogg, K. J., Johnson, M. J., Petrie, M. C., & McMurray, J. J. (2015). Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design. ESC Heart Failure, 2(1), 25-36. https://doi.org/10.1002/ehf2.12027

Abstract Aims The primary aim of this study is to provide data to inform the design of a randomized controlled clinical trial (RCT) of a palliative care (PC) intervention in heart failure (HF). We will identify an appropriate study population with a... Read More about Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design.

Myocardial fibrosis in stroke survivors (2015)
Journal Article
Wong, K., Sze, S., Wong, S., McSwiggan, S., Allgar, V., MacWalter, R., & Struthers, A. D. (2015). Myocardial fibrosis in stroke survivors. International journal of cardiology, 187(1), 138-140. https://doi.org/10.1016/j.ijcard.2015.03.212

Stroke survivors are most likely to die of cardiac death, yet few undergo comprehensive cardiac assessment to look for reversible causes. Myocardial fibrosis (MF) is not only the hallmark of cardiomyopathy, but also a substrate for sudden cardiac dea... Read More about Myocardial fibrosis in stroke survivors.

Insights into the processes of suicide contagion: narratives from young people bereaved by suicide (2015)
Journal Article
Bell, J., Stanley, N., Mallon, S., & Manthorpe, J. (2015). Insights into the processes of suicide contagion: narratives from young people bereaved by suicide. Suicidology online, 6(1), 43-52

Death by suicide can have a profound and long lasting impact on the people left behind. Research has demonstrated that, in comparison to the general population, those bereaved by suicide, particularly young people, are at increased risk for suicide.... Read More about Insights into the processes of suicide contagion: narratives from young people bereaved by suicide.

How will the 'molecular revolution' contribute to biological recording? (2015)
Journal Article
Lawson Handley, L. (2015). How will the 'molecular revolution' contribute to biological recording?. Biological journal of the Linnean Society, 115(3), 750-766. https://doi.org/10.1111/bij.12516

© 2015 The Linnean Society of London. Soaring throughput, plummeting costs, and increased sensitivity for assaying degraded or low-concentration DNA are driving a revolution in the way that we monitor biodiversity. Arguably the biggest 'game-changer'... Read More about How will the 'molecular revolution' contribute to biological recording?.