Deathly triangle for pancreatic β-cells: Hippo pathway-MTORC1-autophagy
(2021)
Journal Article
Ardestani, A., & Maedler, K. (2021). Deathly triangle for pancreatic β-cells: Hippo pathway-MTORC1-autophagy. Autophagy, 17(12), 4494-4496. https://doi.org/10.1080/15548627.2021.1972404
A progressive decline in the macroautophagic/autophagic flux is a hallmark of pancreatic β-cell failure in type 2 diabetes (T2D) but the responsible intrinsic factors and underlying molecular mechanisms are incompletely understood. A stress-sensitive... Read More about Deathly triangle for pancreatic β-cells: Hippo pathway-MTORC1-autophagy.