Professor Matthew Hardman's Projects (20)

Patients and clinicians experiences of hair cycle modulation to facilitate wound healing: a qualitative study within a trial (SWAT) Jan 1, 2024 - Jun 30, 2025
Background: Chronic wounds, delayed healing and surgical site infection affect a significant number of patients. They substantially decrease quality of life and can lead to repeated hospital admission, social isolation, chronic pain limb loss and dea... Read More about Patients and clinicians experiences of hair cycle modulation to facilitate wound healing: a qualitative study within a trial (SWAT).

HIKE: Generating a Pre-Clinical Data Package to Support Commercialisation and Clinical Translation of Novel Regenerative Scaffolds for Chronic Wounds Jul 30, 2023 - Mar 31, 2024
This is an application to the University's HIKE funding scheme - MRC Confidence in Concept

Wolfson Equipment bid 2023 - Confocal Imaging ZEISS Elyra 7 with Lattice SIM² Oct 1, 2024 - Sep 30, 2029

Identification of Fungal Microbiome Signatures in Patients with Blood Cancers Treated in the BioDrive AFS study Feb 1, 2023 - Jan 31, 2027

Micreos Contribution to NBIC Studentship Jan 1, 2023 - Dec 31, 2026
Consumables top-up for the NBIC studentship, WT project: 3923886

First-in-man clinical trial investigating the effect of hair cycle modulation on wound healing Mar 1, 2023 - Jan 31, 2025
Background: Chronic wounds, delayed healing and surgical site infection affect a significant number of patients and come at great cost to healthcare providers. They substantially decrease quality of life and may lead to repeated hospital admission, s... Read More about First-in-man clinical trial investigating the effect of hair cycle modulation on wound healing.

A novel, first-in-its-kind, aptamer-based LYTACs to address the unmet clinical need of diabetic wounds. Dec 1, 2022 - Nov 30, 2027

PreclinHUPET2: Enabling Enhanced Preclinical Nuclear Imaging For The North Of England Feb 1, 2023 - Jan 31, 2024
The grant application is to upgrade the preclinical scanning facilities for nuclear imaging of small animals (mice and rats) at the University of Hull. These facilities are used for research into disease and human health. The main areas that will be... Read More about PreclinHUPET2: Enabling Enhanced Preclinical Nuclear Imaging For The North Of England.

RISE: Establishing super-Resolution Imaging in Hull for impactful multimorbidity ReSEarch MRC Equipment bid 2024 - Confocal Imaging ZEISS Elyra 7 with Lattice SIM² Oct 1, 2024 - Sep 30, 2029

A cell model for discovering biomarkers and druggable targets for pulmonary fibrosis May 1, 2023 - Jan 31, 2025

Using novel endolysins to selectively target antimicrobial resistant S. aureus in chronic wound biofilms Jan 1, 2023 - Dec 31, 2026
This cutting-edge PhD project will bring together a world-leading team spanning industry and academia, providing an interdisciplinary framework to explore the selectivity and efficacy of endolysin against clinically meaningful S. aureus wound biofilm... Read More about Using novel endolysins to selectively target antimicrobial resistant S. aureus in chronic wound biofilms.

Depilation Feasibility PPI: The Impact of Depilation upon Wound Healing and Post-Surgical Complications: A Feasibility Study (The DEPILATION-Feasibility STUDY) - Patient and Public Involvement Jul 1, 2021 - Jun 30, 2022
Wound complications such as infection or dehiscence (where all or part of the wound bursts open) are the most common complication following surgery. The cost of infection alone to the NHS may be upwards of £700 million every year.

Infections are m... Read More about Depilation Feasibility PPI: The Impact of Depilation upon Wound Healing and Post-Surgical Complications: A Feasibility Study (The DEPILATION-Feasibility STUDY) - Patient and Public Involvement.

Endolysin technology for selective management of MRSA biofilms on skin and wounds Sep 1, 2021 - Apr 30, 2022

Bacterial Modulation of Cellular Senescence in Impaired Skin Healing Apr 1, 2022 - Mar 31, 2025

Re-Purposing Anti-Ageing Drugs to Heal Diabetic Foot Ulcers Sep 30, 2021 - Sep 29, 2024
Diabetes UK PhD Studentship application.

Development of fully humanised ex vivo human skin wound and infection model Jul 1, 2019 - Sep 2, 2019
Summer Studentship Project 2019

Development of an immune-responsive 3D skin model May 1, 2019 - Jul 31, 2019
The immune system is an essential regulator of normal physiologic and wound repair processes within the skin, and it contributes to the progression of many different skin diseases. The nature of the interactions between circulating immune cells and r... Read More about Development of an immune-responsive 3D skin model.

Development and application of a new technology for the targeted management of biofilms in human chronic wounds Nov 1, 2018 - Oct 31, 2019

MICA: The role of arginase in chronic delayed wound healing Aug 1, 2016 - Oct 17, 2017

The role of bacteria in the skin: Cold atmospheric plasma for the treatment of pathological skin healing Apr 1, 2017 - Mar 31, 2020
Chronic wounds remain a major area of unmet clinical need, with infection a principle contributing factor to wound chronicity. This project builds upon strong preliminary data suggesting that healing outcome can be directly linked to both wound micro... Read More about The role of bacteria in the skin: Cold atmospheric plasma for the treatment of pathological skin healing.