NERC Discipline Hopping: Fish on chips: developing a new microfluidics model as a tool for testing and mitigating the effects of environmental and biological contaminants on fish

Dr Domino Joyce D.Joyce@hull.ac.uk
Senior Lecturer

Dr Pedro Beltran-Alvarez P.Beltran-Alvarez@hull.ac.uk
Senior Lecturer in Health and Climate Change and Programme co-Director of the MSc Health and Climate Change

Professor John Greenman J.Greenman@hull.ac.uk
Professor of Tumour Immunology

Blood test for clinical therapy guidance of non-small cell lung cancer patients Jan 1, 2017 - Oct 31, 2022
Lung cancer is the most common cancer worldwide. NSCLC alone make up about 75% of all lung cancers and most hospitals currently test all NSCLC patients for EGFR mutations (pharmacogenomics) for treatment decision (personalised medicine) – i.e., patie... Read More about Blood test for clinical therapy guidance of non-small cell lung cancer patients.

The effect of corticosteroids on the release of immune modulating factors from Graves’ disease tissue maintained using microfluidic culture. Jun 1, 2017 - May 31, 2018
Graves’ disease (GD) affects approximately 2% of adult women. Current treatments for GD include anti-thyroid drugs, radioiodine therapy and surgery, of which none tackle the underlying pathogenic process. Immunosuppressive agents are therefore of gro... Read More about The effect of corticosteroids on the release of immune modulating factors from Graves’ disease tissue maintained using microfluidic culture..

Development of a multipurpose small animal phantom for pre-clinical radiotherapy studies Apr 1, 2016 - Mar 31, 2019
The project aims to both reduce the total number of animals used for preclinical radiotherapy experiments whilst concurrently increasing the accuracy of such investigations in order to maximise their clinical impact. This will be achieved through the... Read More about Development of a multipurpose small animal phantom for pre-clinical radiotherapy studies.

The Hull-Norwich Gut-Brian Study May 31, 2016 - Jun 30, 2018
Objective To obtain mechanistic insights into how resident commensal gut bacteria (the microbiota) influences host physiology and in particular brain function and host behaviour. The focus is on identifying the pathways and molecules originating from... Read More about The Hull-Norwich Gut-Brian Study.

Lab on a Chip NC3Rs Engagement Award Aug 15, 2016 - Aug 14, 2017
This project will deliver a programme of public engagement with innovative hands-on activities in the area of tissue/organ-on-a-chip which are emerging as life-like models to reduce and replace animal testing to school children and the general public... Read More about Lab on a Chip NC3Rs Engagement Award.