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Projects (158)

Using a custom-designed spheroid-on chip model to study impact of sheer stress under low oxygen conditions Jul 1, 2022 - Dec 31, 2022
Metastatic, or secondary, cancer has particularly poor prognosis, accounting for up to 90% of all cancer deaths. Therefore, identification and validation of early metastasis biomarkers and/or defining metastasis-specific therapeutic targets is essent... Read More about Using a custom-designed spheroid-on chip model to study impact of sheer stress under low oxygen conditions.

Quantitative proteomic analysis of pancreatic cyst fluid for early detection of cancer using University of Hull HPC Viper Apr 1, 2022 - Feb 28, 2023
The timely diagnosis of pancreatic ductal adenocarcinoma (PDAC) is challenging due to a lack of disease-specific symptoms, resulting in the majority of patients presenting with advanced disease and poor prognosis. Detection of PDAC, ideally at a prem... Read More about Quantitative proteomic analysis of pancreatic cyst fluid for early detection of cancer using University of Hull HPC Viper.

Equipment - orbital shaker Aug 1, 2022 - Jul 31, 2023
Endometriosis affects 1 in 10 women worldwide, the same frequency as diabetes but it has had a tiny amount of research funding in comparison. Endometriosis causes debilitating pain that can lead to loss of work, impact mental health and is a major ca... Read More about Equipment - orbital shaker.

TARGETING THE MYOSIN LIGHT CHAIN PHOSPHATASE WITH PEPTIDE DISRUPTORS: A NOVEL ANTIPLATELET THERAPEUTIC APPROACH Jul 3, 2023 - Jul 2, 2026
Platelet activation and thrombus formation play key roles in the pathogenesis of ischaemic cardiovascular diseases, one of the major causes of death in the UK. Many antiplatelet agents have been developed to manage these conditions; however, they are... Read More about TARGETING THE MYOSIN LIGHT CHAIN PHOSPHATASE WITH PEPTIDE DISRUPTORS: A NOVEL ANTIPLATELET THERAPEUTIC APPROACH.