Outputs (66)

Hepatocellular adenoma in a European flatfish (Limanda limanda) : genetic alterations in laser-capture microdissected tissue and global transcriptomic approach (2017)
Journal Article
Lerebours, A., Lyons, B. P., Bignell, J. P., Stentiford, G. D., Rotchell, J. M., Lerebours, A., Chapman, E., Rotchell, J., Bignell, J., Lyons, B., & Stentiford, G. (2017). Hepatocellular adenoma in a European flatfish (Limanda limanda) : genetic alterations in laser-capture microdissected tissue and global transcriptomic approach. Marine pollution bulletin, 119(2), 120-127. https://doi.org/10.1016/j.marpolbul.2017.04.052

Liver tumours in flatfish have been diagnosed using histopathology for decades to monitor the impacts of marine pollution. Here we describe the application of specific gene (retinoblastoma, Rb) profiling in laser capture micro-dissected samples, and... Read More about Hepatocellular adenoma in a European flatfish (Limanda limanda) : genetic alterations in laser-capture microdissected tissue and global transcriptomic approach.

Molecular changes in skin pigmented lesions of the coral trout Plectropomus leopardus (2016)
Journal Article
Lerebours, A., Chapman, E. C., Rotchell, J. M., Heupel, M. R., & Sweet, M. J. (2016). Molecular changes in skin pigmented lesions of the coral trout Plectropomus leopardus. Marine environmental research, 120, 130-135. https://doi.org/10.1016/j.marenvres.2016.07.009

© 2016 Elsevier Ltd A high prevalence of skin pigmented lesions of 15% was recently reported in coral trout Plectropomus leopardus, a commercially important marine fish, inhabiting the Great Barrier Reef. Herein, fish were sampled at two offshore sit... Read More about Molecular changes in skin pigmented lesions of the coral trout Plectropomus leopardus.

Environmental concentration of carbamazepine accelerates fish embryonic development and disturbs larvae behavior (2016)
Journal Article
Qiang, L., Cheng, J., Yi, J., Rotchell, J. M., Zhu, X., & Zhou, J. (2016). Environmental concentration of carbamazepine accelerates fish embryonic development and disturbs larvae behavior. Ecotoxicology, 25(7), 1426-1437. https://doi.org/10.1007/s10646-016-1694-y

Environmental pollution caused by pharmaceuticals has been recognized as a major threat to the aquatic ecosystems. Carbamazepine, as the widely prescribed antiepileptic drug, has been frequently detected in the aquatic environment and has created con... Read More about Environmental concentration of carbamazepine accelerates fish embryonic development and disturbs larvae behavior.

Short-term effects of CO₂-induced low pH exposure on target gene expression in Platynereis dumerilii (2016)
Journal Article
Wäge, J., Rohr, S., Hardege, J. D., & Rotchell, J. M. (2016). Short-term effects of CO₂-induced low pH exposure on target gene expression in Platynereis dumerilii. Journal of Marine Biology and Oceanography, 5(2), https://doi.org/10.4172/2324-8661.1000155

Objective: Increasing atmospheric CO₂ concentration are causing changes to the seawater carbonate chemistry, lowering the pH and we study potential impacts of these changes at the molecular level in a non-calcifying, marine polychaete species Platyne... Read More about Short-term effects of CO₂-induced low pH exposure on target gene expression in Platynereis dumerilii.

Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii (2015)
Journal Article
Wäge, J., Lerebours, A., Hardege, J. D., & Rotchell, J. M. (2016). Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii. Ecotoxicology and environmental safety, 124(February), 105-110. https://doi.org/10.1016/j.ecoenv.2015.10.008

© 2015 Elsevier Inc. Fossil fuel emissions and changes in net land use lead to an increase in atmospheric CO 2 concentration and a subsequent decrease of ocean pH. Noticeable effects on organisms' calcification rate, shell structure and energy metabo... Read More about Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii.

Erratum: Identification of reproduction-specific genes associated with maturation and estrogen exposure in a marine bivalve mytilus edulis (PLoS ONE (2015) 10:7 (e0132080) DOI: :10.1371/journal.pone.0132080) (2015)
Journal Article
Ciocan, C. M., Cubero-Leon, E., Minier, C., & Rotchell, J. M. (2015). Erratum: Identification of reproduction-specific genes associated with maturation and estrogen exposure in a marine bivalve mytilus edulis (PLoS ONE (2015) 10:7 (e0132080) DOI: :10.1371/journal.pone.0132080). PLoS ONE, 10(7), Article e0132080. https://doi.org/10.1371/journal.pone.0132080

Fig 1 of the published article is incomplete. Please view the complete Fig 1 and its legend here.

Silver nanoparticles affect the neural development of zebrafish embryos: AgNPs affect the embryonic neural development (2015)
Journal Article
Xin, Q., Rotchell, J. M., Cheng, J., Yi, J., & Zhang, Q. (2015). Silver nanoparticles affect the neural development of zebrafish embryos: AgNPs affect the embryonic neural development. Journal of Applied Toxicology, 35(12), 1481-1492. https://doi.org/10.1002/jat.3164

Silver nanoparticles (AgNPs) have been widely used in commercial products. This study aims to understand the impact of AgNPs on the early developmental stages in zebrafish (Danio rerio) embryos. Embryos were exposed to two sizes of AgNPs at three dos... Read More about Silver nanoparticles affect the neural development of zebrafish embryos: AgNPs affect the embryonic neural development.

Effects of low seawater pH on the marine polychaete Platynereis dumerilii (2015)
Journal Article
Wäge, J., Hardege, J. D., Larsson, T. A., Simakov, O., Chapman, E. C., Arendt, D., & Rotchell, J. M. (2015). Effects of low seawater pH on the marine polychaete Platynereis dumerilii. Marine pollution bulletin, 95(1), 166-172. https://doi.org/10.1016/j.marpolbul.2015.04.027

An important priority for any organism is to maintain internal cellular homeostasis including acidbase balance. Yet, the molecular level impacts of changing environmental conditions, such as low pH, remain uncharacterised. Herein, we isolate partial... Read More about Effects of low seawater pH on the marine polychaete Platynereis dumerilii.

Molecular characterization of an estrogen receptor and estrogen-related receptor and their autoregulatory capabilities in two Mytilus species (2015)
Journal Article
Nagasawa, K., Treen, N., Kondo, R., Otoki, Y., Itoh, N., Rotchell, J. M., & Osada, M. (2015). Molecular characterization of an estrogen receptor and estrogen-related receptor and their autoregulatory capabilities in two Mytilus species. Gene, 564(2), 153-159. https://doi.org/10.1016/j.gene.2015.03.073

Vertebrate-like sex steroid hormones have been widely detected in mollusks, and numerous experiments have shown the importance of steroids in gonad development. Nevertheless, their signaling pathways in invertebrates have not been uncovered yet. Ster... Read More about Molecular characterization of an estrogen receptor and estrogen-related receptor and their autoregulatory capabilities in two Mytilus species.

Intersex related gene expression profiles in clams Scrobicularia plana : molecular markers and environmental application (2015)
Journal Article
Langston, W. J., Ciocan, C. M., Hill, E. M., Lerebours, A., Rotchell, J. M., Rotchell, J., Alvarez-Munoz, D., Ciocan, C., Cornelius, K., Cubero-Leon, E., Hill, E., Indiveri, P., Langston, W., Minier, C., & Pope, N. (2015). Intersex related gene expression profiles in clams Scrobicularia plana : molecular markers and environmental application. Marine pollution bulletin, 95(2), 610-617. https://doi.org/10.1016/j.marpolbul.2015.02.019

Intersex, the appearance of female characteristics in male gonads, has been identified in several aquatic species. It is a widespread phenomenon in populations of the bivalve, Scrobicularia plana, from the southwest coast of the U.K. Genes previously... Read More about Intersex related gene expression profiles in clams Scrobicularia plana : molecular markers and environmental application.