PKCα regulates platelet granule secretion and thrombus formation in mice
(2009)
Journal Article
Konopatskaya, O., Gilio, K., Harper, M. T., Zhao, Y., Cosemans, J. M. E. M., Karim, Z. A., Whiteheart, S. W., Molkentin, J. D., Verkade, P., Watson, S. P., Heemskerk, J. W. M., & Poole, A. W. (2009). PKCα regulates platelet granule secretion and thrombus formation in mice. Journal of Clinical Investigation, 119(2), 399-407. https://doi.org/10.1172/JCI34665
Platelets are central players in atherothrombosis development in coronary artery disease. The PKC family provides important intracellular mechanisms for regulating platelet activity, and platelets express several members of this family, including the... Read More about PKCα regulates platelet granule secretion and thrombus formation in mice.