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Assessment of the diagnostic accuracy of automated ankle brachial pressure index devices in patients with diagnosed or suspected peripheral arterial disease: protocol for a systematic review and meta-analysis (2022)
Journal Article
Walshaw, J., Lathan, R., Huang, C., Staniland, T., Chetter, I., & Pymer, S. (2023). Assessment of the diagnostic accuracy of automated ankle brachial pressure index devices in patients with diagnosed or suspected peripheral arterial disease: protocol for a systematic review and meta-analysis. Journal of Vascular Societies Great Britain and Ireland, 2(2), 91-96. https://doi.org/10.54522/jvsgbi.2022.053

Background: The ankle brachial pressure index (ABPI) is a common diagnostic tool used in the assessment of peripheral arterial disease (PAD). The Doppler ultrasound technique is regarded as the gold-standard method for ABPI measurement; however, time... Read More about Assessment of the diagnostic accuracy of automated ankle brachial pressure index devices in patients with diagnosed or suspected peripheral arterial disease: protocol for a systematic review and meta-analysis.

Assessing the androgenic and metabolic heterogeneity in polycystic ovary syndrome using cluster analysis (2022)
Journal Article
Deshmukh, H., Akbar, S., Bhaiji, A., Saeed, Y., Shah, N., Adeleke, K., Papageorgiou, M., Atkin, S., & Sathyapalan, T. (2023). Assessing the androgenic and metabolic heterogeneity in polycystic ovary syndrome using cluster analysis. Clinical Endocrinology, 98(3), 400-406. https://doi.org/10.1111/cen.14847

Introduction: Some but not all women with polycystic ovary syndrome (PCOS) develop the metabolic syndrome (MS). The objective of this study was to determine if a subset of women with PCOS had higher androgen levels predisposing them to MS and whether... Read More about Assessing the androgenic and metabolic heterogeneity in polycystic ovary syndrome using cluster analysis.

Renal Effects of Empagliflozin in Patients with Type 2 Diabetes Mellitus (2022)
Journal Article
Yaribeygi, H., Maleki, M., Sathyapalan, T., Jamialahmadi, T., & Sahebkar, A. (2022). Renal Effects of Empagliflozin in Patients with Type 2 Diabetes Mellitus. Current medicinal chemistry, 30(25), 2850-2863. https://doi.org/10.2174/0929867329666220831151645

Type 2 diabetes mellitus (T2DM) is one of the main causes of mortality and morbidity worldwide. It leads to various long-term complications such as diabetic nephropathy. Diabetes nephropathy is the leading cause of renal failure in patients with chro... Read More about Renal Effects of Empagliflozin in Patients with Type 2 Diabetes Mellitus.

Changes in functional health status following open abdominal aortic aneurysm repair and the role of exercise-based rehabilitation: protocol for a systematic review and meta-analysis (2022)
Journal Article
Ravindhran, B., Lathan, R., Staniland, T., Sidapra, M., Carradice, D., Chetter, I., Smith, G., Saxton, J., & Pymer, S. (2022). Changes in functional health status following open abdominal aortic aneurysm repair and the role of exercise-based rehabilitation: protocol for a systematic review and meta-analysis. Journal of Vascular Societies Great Britain and Ireland, 2(1), 41-45. https://doi.org/10.54522/jvsgbi.2022.042

Background and objectives: The aim of this systematic review is to explore the current evidence surrounding the changes in functional status following open or endovascular abdominal aortic aneurysm (AAA) repair and the role of postoperative exercise-... Read More about Changes in functional health status following open abdominal aortic aneurysm repair and the role of exercise-based rehabilitation: protocol for a systematic review and meta-analysis.

Age-Associated Changes in Voltage-Gated Sodium Channels Within the Right Atrium Predispose the Elderly to Atrial Fibrillation (2022)
Thesis
Isaac, E. S. Age-Associated Changes in Voltage-Gated Sodium Channels Within the Right Atrium Predispose the Elderly to Atrial Fibrillation. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4508137

Atrial Fibrillation (AF) is the most common cardiac arrhythmia worldwide with sufferers of the condition facing significant morbidity and mortality. Ageing alone is identified as the most significant risk factor for developing the arrhythmia. As such... Read More about Age-Associated Changes in Voltage-Gated Sodium Channels Within the Right Atrium Predispose the Elderly to Atrial Fibrillation.

Cancer patients’ experiences of the diagnosis and treatment of incidental pulmonary embolism (a qualitative study) (2022)
Journal Article
Benelhaj, N. E., Hutchinson, A., Maraveyas, A., & Johnson, M. (2022). Cancer patients’ experiences of the diagnosis and treatment of incidental pulmonary embolism (a qualitative study). PLoS ONE, 17(10), Article e0276754. https://doi.org/10.1371/journal.pone.0276754

Background: The diagnosis of symptomatic cancer-associated thrombosis often causes distress and alarm for patients, especially for those unaware of the risk, or the signs and symptoms to look out for. There are few data about cancer patients’ experie... Read More about Cancer patients’ experiences of the diagnosis and treatment of incidental pulmonary embolism (a qualitative study).

The Role of High-density Lipoprotein in Oral and Dental Diseases (2022)
Journal Article
Sadeghalbanaei, L., Shirban, F., Bagherniya, M., Sathyapalan, T., & Sahebkar, A. (2023). The Role of High-density Lipoprotein in Oral and Dental Diseases. Current medicinal chemistry, 30(20), 2226-2246. https://doi.org/10.2174/0929867329666220901120654

High-density lipoprotein (HDL) is the smallest and densest of the lipoproteins. Beyond its well-known cardiovascular protective function, it has other actions, including structural function, anti-inflammatory, antioxidant, anti-thrombotic effects, tr... Read More about The Role of High-density Lipoprotein in Oral and Dental Diseases.

Do we need routine antibiotics for hand surgery? (2022)
Presentation / Conference Contribution
Wormald, J., & Totty, J. (2022, October). Do we need routine antibiotics for hand surgery?. Paper presented at British Society for Surgery of the Hand (BSSH) Autumn Scientific Meeting 2022, Winchester, UK

Both the incidence of hand trauma, and the demand for elective hand surgery, continue to rise in the UK. The incidence of surgical site infection (SSI) following hand surgery is around 5%. Traditionally, antibiotic prophylaxis at the time of surgery... Read More about Do we need routine antibiotics for hand surgery?.

The DEFINITE Audit - A Prospective Audit of Diabetic Foot Debridement in Theatre: A Protocol (2022)
Journal Article
Hitchman, L. (in press). The DEFINITE Audit - A Prospective Audit of Diabetic Foot Debridement in Theatre: A Protocol. Journal of Vascular Societies Great Britain and Ireland,

Background
People with diabetes are commonly affected by foot ulceration (DFU) and subsequent or concurrent infection (DFI). Surgical debridement is often needed to contain infection. Despite international guidelines, there remains significant vari... Read More about The DEFINITE Audit - A Prospective Audit of Diabetic Foot Debridement in Theatre: A Protocol.

Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials (2022)
Journal Article
Abdalla, M. A., Shah, N., Deshmukh, H., Sahebkar, A., Östlundh, L., Al-Rifai, R. H., Atkin, S. L., & Sathyapalan, T. (2022). Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials. Therapeutic Advances in Endocrinology and Metabolism, 13, https://doi.org/10.1177/20420188221127142

Context: Polycystic ovary syndrome (PCOS) is one of the commonest endocrine disorders affecting women of reproductive age, and metformin is a widely used medication in managing this condition. Aim: To review the available literature comprehensively o... Read More about Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials.