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Effect of treatment planning system parameters on beam modulation complexity for treatment plans with single-layer multi-leaf collimator and dual-layer stacked multi-leaf collimator

Quintero, Paulo; Cheng, Yongqiang; Benoit, David; Moore, Craig; Beavis, Andrew

Authors

Paulo Quintero

Yongqiang Cheng

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Dr David Benoit D.Benoit@hull.ac.uk
Senior Lecturer in Molecular Physics and Astrochemistry

Craig Moore



Abstract

OBJECTIVE: High levels of beam modulation complexity (MC) and monitor units (MU) can compromise the plan deliverability of intensity-modulated radiotherapy treatments. Our study evaluates the effect of three treatment planning system (TPS) parameters on MC and MU using different multi-leaf collimator (MLC) architectures. METHODS: 192 volumetric modulated arc therapy plans were calculated using one virtual prostate phantom considering three main settings: (1) three TPS-parameters (Convergence; Aperture Shape Controller, ASC; and Dose Calculation Resolution, DCR) selected from Eclipse v15.6, (2) four levels of dose-sparing priority for organs at risk (OAR), and (3) two treatment units with same nominal conformity resolution and different MLC architectures (Halcyon-v2 dual-layer MLC, DL-MLC & TrueBeam single-layer MLC, SL-MLC). We use seven complexity metrics to evaluate the MC, including two new metrics for DL-MLC, assessed by their correlation with γ passing rate (GPR) analysis. RESULTS: DL-MLC plans demonstrated lower dose-sparing values than SL-MLC plans (p

Citation

Quintero, P., Cheng, Y., Benoit, D., Moore, C., & Beavis, A. (2021). Effect of treatment planning system parameters on beam modulation complexity for treatment plans with single-layer multi-leaf collimator and dual-layer stacked multi-leaf collimator. British Journal of Radiology, 94(1122), Article 20201011. https://doi.org/10.1259/bjr.20201011

Journal Article Type Article
Acceptance Date Mar 18, 2021
Online Publication Date Apr 29, 2021
Publication Date Jun 1, 2021
Deposit Date Apr 7, 2022
Publicly Available Date Apr 30, 2022
Journal The British journal of radiology
Print ISSN 0007-1285
Electronic ISSN 1748-880X
Publisher British Institute of Radiology
Peer Reviewed Peer Reviewed
Volume 94
Issue 1122
Article Number 20201011
DOI https://doi.org/10.1259/bjr.20201011
Public URL https://hull-repository.worktribe.com/output/3809361

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