Reductive Amination-A convenient method for generating diverse, mono-functionalised 5,10,15,20-tetraphenyl porphyrins

Welch, Chris; Archibald, Stephen; Welch, Christopher; Archibald, Stephen J.; Boyle, Ross

Abstract

Formylation followed by reductive amination of 5,10,15,20-tetraphenyl porphyrin (TPP) is shown to be a versatile synthetic procedure for monosubstitution of the porphyrin core re-giospecifically at one β-position. A diverse range of substituents can be introduced in this way in good yields, including cyclen aza-crown macrocycles. © Georg Thieme Verlag Stuttgart.

Citation

Welch, C., Archibald, S. J., & Boyle, R. (2009). Reductive Amination-A convenient method for generating diverse, mono-functionalised 5,10,15,20-tetraphenyl porphyrins. SYNTHESIS, 2009(4), 551-556. https://doi.org/10.1055/s-0028-1083335

• Journal Article Type: Article
• Online Publication Date: Jan 27, 2009
• Publication Date: 2009-01
• Journal: SYNTHESIS-STUTTGART
• Print ISSN: 0039-7881
• Electronic ISSN: 1437-210X
• Publisher: Thieme Gruppe
• Peer Reviewed: Peer Reviewed
• Volume: 2009
• Issue: 4
• Pages: 551-556
• DOI: https://doi.org/10.1055/s-0028-1083335
• Keywords: porphyrin, conjugation, macrocycle
• Public URL: https://hull-repository.worktribe.com/output/395920
• Publisher URL: https://www.thieme-connect.com/ejournals/abstract/10.1055/s-0028-1083335