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Reply to “Analysis of NO and its metabolites by mass spectrometry. Comment on ‘Detection of nitric oxide in tissue samples by ESI-MS’”

Dyer, Charlotte E.; Haswell, Stephen J.; Webster, Abigail; Zheng, Shen; Haswell, Stephen J.; Greenman, John; Greenman, John; Welham, Kevin J.; Webster, Abigail; Zheng, Shen; Greenman, John; Dyer, Charlotte E.; Dyer, Charlotte E.; Welham, Kevin J.; Webster, Abigail; Zheng, Shen; Haswell, Stephen J.; Zheng, Shen; Zheng, Shen; Welham, Kevin J.; Webster, Abigail; Webster, Abigail; Welham, Kevin; Welham, Kevin J.; Dyer, Charlotte E.; Dyer, Charlotte E.; Greenman, John; Greenman, John; Haswell, Stephen J.; Haswell, Stephen J.

Authors

Charlotte E. Dyer

Stephen J. Haswell

Abigail Webster

Shen Zheng

Stephen J. Haswell

Kevin J. Welham

Abigail Webster

Shen Zheng

Charlotte E. Dyer

Charlotte E. Dyer

Kevin J. Welham

Abigail Webster

Shen Zheng

Stephen J. Haswell

Shen Zheng

Shen Zheng

Kevin J. Welham

Abigail Webster

Abigail Webster

Kevin Welham K.J.Welham@hull.ac.uk

Kevin J. Welham

Stephen J. Haswell

Stephen J. Haswell



Abstract

Comment by Tsikas et al. (Analyst, 2011, DOI: 10.1039/c0an00411a) on the preliminary work by Shen and colleagues (Analyst, 2010, 135, 302) describing the use of ESI-MS/MS for the detection of methylpiperazinobenzenediamine, as a probe for NO in tissue samples, have been addressed in this communication. The article concludes that the points raised by Tsikas represent a logical progression to the research reported and indicate the way forward in realising appropriate analytical methodology.

Citation

Zheng, S., Webster, A., Zheng, S., Welham, K. J., Dyer, C. E., Greenman, J., …Haswell, S. J. (2011). Reply to “Analysis of NO and its metabolites by mass spectrometry. Comment on ‘Detection of nitric oxide in tissue samples by ESI-MS’”. Analyst, 136(2), 411-411. https://doi.org/10.1039/c0an00729c

Journal Article Type Article
Acceptance Date Dec 31, 2011
Publication Date Dec 31, 2011
Journal ANALYST
Print ISSN 0003-2654
Electronic ISSN 1364-5528
Publisher Royal Society of Chemistry
Volume 136
Issue 2
Pages 411-411
DOI https://doi.org/10.1039/c0an00729c
Keywords Analytical Chemistry; Spectroscopy; Electrochemistry; Biochemistry; Environmental Chemistry
Public URL https://hull-repository.worktribe.com/output/396322