ObjectiveMany venous trials mix patients with great saphenous vein (GSV) and small saphenous vein (SSV) diseases. There is no evidence that both respond similarly to treatment and our aim was to test this assumption.Method This cohort study compares patients with isolated GSV and SSV incompetence following treatment with open surgical ligation or endovenous laser ablation (EVLA). Outcomes included: quality of life (QoL; Aberdeen Varicose Vein Questionnaire [AVVQ]; Short Form 36 [SF36]; Euroqol [EQ5D]; and Venous Clinical Severity Score [VCSS]).ResultsA total of 370 patients with no differences in baseline QoL, underwent treatment. Despite equivalent morbidity, SSV sufferers had a lower VCSS (P < 0.001). Following surgery, SSV patients scored higher (worse) on AVVQ (P = 0.045) than GSV sufferers, but lower (better) following EVLA (P = 0.042). ConclusionThe morbidity associated with SSV incompetence is greater than suggested by its clinical severity and responds differently following treatment to that of the GSV. Trials should consider patients with GSV and SSV reflux separately. EVLA may offer additional benefits to SSV sufferers.
Hatfield, J., Carradice, D., Mazari, F. A. K., Josie, H., Samuel, N., Chetter, I., & Wallace, T. (2012). Comparing the treatment response of great saphenous and small saphenous vein incompetence following surgery and endovenous laser ablation: a retrospective cohort study. Phlebology, 27(3), 128-134. https://doi.org/10.1258/phleb.2011.011014