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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 (2024)
Journal Article
Vollset, S. E., Ababneh, H. S., Abate, Y. H., Abbafati, C., Abbasgholizadeh, R., Abbasian, M., …Soyiri, I. (2024). Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021. Lancet, 403(10440), 2204-2256. https://doi.org/10.1016/S0140-6736%2824%2900685-8

Background: Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded... Read More about Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021.

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 (2024)
Journal Article
Brauer, M., Roth, G. A., & Soyiri, I. (2024). Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet, 403(10440), 2162-2203. https://doi.org/10.1016/S0140-6736%2824%2900933-4

Background: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, th... Read More about Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021.

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 (2024)
Journal Article
Naghavi, M., Ong, K. L., & Soyiri, I. (2024). Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet, 403(10440), 2100-2132. https://doi.org/10.1016/S0140-6736%2824%2900367-2

Background: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable met... Read More about Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021.

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 (2024)
Journal Article
Schumacher, A. E., Hmwe Kyu, H., & Soyiri, I. N. (2024). Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021. Lancet, 403(10440), 1989-2056. https://doi.org/10.1016/S0140-6736%2824%2900476-8

Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this... Read More about Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021.

Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study (2024)
Journal Article
Cuthbert, J. J., Soyiri, I., Lomax, S. J., Turgoose, J., Fuat, A., Cohen, J., & Clark, A. L. (2024). Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study. Heart, 110(12), Article 323577. https://doi.org/10.1136/heartjnl-2023-323577

Background Loop diuretics are commonly prescribed in the community, not always to patients with a recorded diagnosis of heart failure (HF). The rate of HF events in patients prescribed loop diuretics without a diagnosis of HF is unknown. Methods... Read More about Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study.

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 (2024)
Journal Article
Ferrari, A. J., Francesco Santomauro, D., & Soyiri, I. (2024). Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet, 403(10440), 2133-2161. https://doi.org/10.1016/S0140-6736%2824%2900757-8

Background: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age... Read More about Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021.

Ethics guidelines for environmental epidemiologists (2024)
Journal Article
Etzel, R. A., Abbas, N. H., Anastario, M. P., Mustapha, A., Osuolale, O., Sarkar, A., …Soskolne, C. L. (2024). Ethics guidelines for environmental epidemiologists. Environmental Epidemiology, 8(2), Article E299. https://doi.org/10.1097/EE9.0000000000000299

Recognition of the importance to environmental epidemiology of ethical and philosophical deliberation led, in 1996, to the establishment of Ethics Guidelines for the profession. In 1999, these guidelines were adopted by the International Society for... Read More about Ethics guidelines for environmental epidemiologists.

Breathlessness limiting exertion in very old adults: findings from the Newcastle 85+ study (2023)
Journal Article
Johnson, M. J., Pitel, L., Currow, D. C., Forbes, C., Soyiri, I., & Robinson, L. (2023). Breathlessness limiting exertion in very old adults: findings from the Newcastle 85+ study. Age and ageing, 52(9), Article afad155. https://doi.org/10.1093/ageing/afad155

INTRODUCTION: Long-term breathlessness is more common with age. However, in the oldest old (>85years), little is known about the prevalence, or impact of breathlessness. We estimated breathlessness limiting exertion prevalence and explored (i) associ... Read More about Breathlessness limiting exertion in very old adults: findings from the Newcastle 85+ study.

Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019 (2023)
Journal Article
Momtazmanesh, S., Moghaddam, S. S., Ghamari, S. H., Rad, E. M., Rezaei, N., Shobeiri, P., …Soyiri, I. (2023). Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019. EClinicalMedicine, 59, Article 101936. https://doi.org/10.1016/j.eclinm.2023.101936

Background: Updated data on chronic respiratory diseases (CRDs) are vital in their prevention, control, and treatment in the path to achieving the third UN Sustainable Development Goals (SDGs), a one-third reduction in premature mortality from non-co... Read More about Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019.

Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000–18: a geospatial modelling study (2022)
Journal Article
Frostad, J. J., Nguyen, Q. A. P., Baumann, M. M., Blacker, B. F., Marczak, L. B., Deshpande, A., …Soyiri, I. (2022). Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000–18: a geospatial modelling study. The Lancet global health, 10(10), e1395-e1411. https://doi.org/10.1016/S2214-109X%2822%2900332-1

Background: More than 3 billion people do not have access to clean energy and primarily use solid fuels to cook. Use of solid fuels generates household air pollution, which was associated with more than 2 million deaths in 2019. Although local patter... Read More about Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000–18: a geospatial modelling study.

Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020 (2022)
Journal Article
Bryazka, D., Reitsma, M. B., Griswold, M. G., Abate, K. H., Abbafati, C., Abbasi-Kangevari, M., …Soyiri, I. (2022). Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020. Lancet, 400(10347), 185-235. https://doi.org/10.1016/S0140-6736%2822%2900847-9

Background: The health risks associated with moderate alcohol consumption continue to be debated. Small amounts of alcohol might lower the risk of some health outcomes but increase the risk of others, suggesting that the overall risk depends, in part... Read More about Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020.

Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM<inf>2·5</inf> air pollution, 1990–2019: an analysis of data from the Global Burden of Disease Study 2019 (2022)
Journal Article
Burkart, K., Causey, K., Cohen, A. J., Wozniak, S. S., Salvi, D. D., Abbafati, C., …Soyiri, I. (2022). Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990–2019: an analysis of data from the Global Burden of Disease Study 2019. The Lancet Planetary Health, 6(7), e586-e600. https://doi.org/10.1016/S2542-5196%2822%2900122-X

Background: Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quant... Read More about Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM<inf>2·5</inf> air pollution, 1990–2019: an analysis of data from the Global Burden of Disease Study 2019.

Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019 (2022)
Journal Article
Peden, A. E., Cullen, P., Francis, K. L., Moeller, H., Peden, M. M., Ye, P., …Soyiri, I. (2022). Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019. The Lancet. Public Health, 7(8), e657-e669. https://doi.org/10.1016/S2468-2667%2822%2900134-7

Background: Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10–24... Read More about Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019.

Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019 (2022)
Journal Article
Armocida, B., Monasta, L., Sawyer, S., Bustreo, F., Segafredo, G., Castelpietra, G., …Soyiri, I. (2022). Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019. The Lancet Child & Adolescent Health, 6(6), 367-383. https://doi.org/10.1016/S2352-4642%2822%2900073-6

Background: Disability and mortality burden of non-communicable diseases (NCDs) have risen worldwide; however, the NCD burden among adolescents remains poorly described in the EU. Methods: Estimates were retrieved from the Global Burden of Diseases,... Read More about Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019.

Mapping routine measles vaccination in low- and middle-income countries (2020)
Journal Article
Local Burden of Disease Vaccine Coverage Collaborators, & Soyiri, I. (2021). Mapping routine measles vaccination in low- and middle-income countries. Nature, 589, 415-419. https://doi.org/10.1038/s41586-020-03043-4

The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-i... Read More about Mapping routine measles vaccination in low- and middle-income countries.

Hormone replacement therapy and asthma onset in menopausal women: National cohort study (2020)
Journal Article
Shah, S. A., Tibble, H., Pillinger, R., McLean, S., Ryan, D., Critchley, H., …Nwaru, B. I. (2020). Hormone replacement therapy and asthma onset in menopausal women: National cohort study. Journal of Allergy and Clinical Immunology, https://doi.org/10.1016/j.jaci.2020.11.024

© 2020 The Authors Background: There is uncertainty about the role of hormonal replacement therapy (HRT) in the development of asthma. Objective: We investigated whether use of HRT and duration of use was associated with risk of development of as... Read More about Hormone replacement therapy and asthma onset in menopausal women: National cohort study.

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries (2020)
Journal Article
GBD 2019 Demographics Collaborators, & Soyiri, I. (2020). Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries. Lancet, 396(10258), 1160-1203. https://doi.org/10.1016/S0140-6736%2820%2930977-6

Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors... Read More about Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries.

Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study (2020)
Journal Article
James, S. L., Bertolacci, G. J., Castle, C. D., Dingels, Z. V., Fox, J. T., Hamilton, E. B., …Vos, T. (2020). Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study. Injury Prevention, 26, i125-i153. https://doi.org/10.1136/injuryprev-2019-043531

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. BACKGROUND: While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disabili... Read More about Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study.

Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17 (2020)
Journal Article
Reiner, R. C., Local Burden of Disease WaSH Collaborators, & Soyiri, I. (2020). Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17. The Lancet global health, 8(9), e1162-e1185. https://doi.org/10.1016/S2214-109X%2820%2930278-3

Background Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolutio... Read More about Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17.

Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators* (2020)
Journal Article
Local Burden of Disease Diarrhoea Collaborators, & Soyiri, I. (2020). Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators*. The Lancet global health, 8(8), e1038-e1060. https://doi.org/10.1016/S2214-109X%2820%2930230-8

Background Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years w... Read More about Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators*.