All Outputs (46)

Circulating endothelial microparticles reduce in concentration following an exercise programme in women with polycystic ovary syndrome (2019)
Journal Article
Kirk, R. J., Madden, L. A., Peart, D. J., Aye, M. M., Atkin, S. L., & Vince, R. V. (2019). Circulating endothelial microparticles reduce in concentration following an exercise programme in women with polycystic ovary syndrome. Frontiers in endocrinology, 10(MAR), Article 200. https://doi.org/10.3389/fendo.2019.00200

Purpose: Endothelial dysfunction is a known comorbidity in women with polycystic ovary syndrome (PCOS). The aim was to assess if supervised, moderate intensity exercise could potentially impact markers of endothelial disruption; endothelial cell deri... Read More about Circulating endothelial microparticles reduce in concentration following an exercise programme in women with polycystic ovary syndrome.

Can sit-to-stand muscle power explain the ability to perform functional tasks in adults with severe obesity? (2018)
Journal Article
Orange, S. T., Marshall, P., Madden, L. A., & Vince, R. V. (2019). Can sit-to-stand muscle power explain the ability to perform functional tasks in adults with severe obesity?. Journal of sports sciences, 37(11), 1227-1234. https://doi.org/10.1080/02640414.2018.1553500

This study examined the relationship between sit-to-stand (STS) power and physical function in adults with severe obesity. Thirty-eight adults (age: 44 ± 12 years; body mass index [BMI]: 45.2 ± 7.8 kg/m2) completed evaluations of STS power, strength... Read More about Can sit-to-stand muscle power explain the ability to perform functional tasks in adults with severe obesity?.

Effects of acute insulin-induced hypoglycaemia on endothelial microparticles in adults with and without type 2 diabetes (2018)
Journal Article
Al-Qaissi, A., Papageorgiou, M., Deshmukh, H., Madden, L. A., Rigby, A., Kilpatrick, E. S., …Sathyapalan, T. (2019). Effects of acute insulin-induced hypoglycaemia on endothelial microparticles in adults with and without type 2 diabetes. Diabetes, Obesity and Metabolism, 21(3), 533-540. https://doi.org/10.1111/dom.13548

Aims Endothelial microparticles (EMPs) are novel surrogate markers of endothelial injury and dysfunction that may be differentially produced in response to acute insulin‐induced hypoglycaemia in adults with and without type 2 diabetes.

Test-Retest reliability of a commercial linear position transducer (GymAware PowerTool) to measure velocity and power in the Back Squat and Bench Press (2018)
Journal Article
Orange, S. T., Metcalfe, J. W., Vince, R. V., Marshall, P., Madden, L. A., & Liefeith, A. (2020). Test-Retest reliability of a commercial linear position transducer (GymAware PowerTool) to measure velocity and power in the Back Squat and Bench Press. Journal of strength and conditioning research, 34(3), 728-737. https://doi.org/10.1519/JSC.0000000000002715

This study examined the test-retest reliability of the GymAware PowerTool (GYM) to measure velocity and power in the free-weight back squat and bench press. Twenty-nine academy rugby league players (age: 17.6 ± 1.0 years; body mass: 87.3 ± 20.8 kg) c... Read More about Test-Retest reliability of a commercial linear position transducer (GymAware PowerTool) to measure velocity and power in the Back Squat and Bench Press.

Validity and reliability of a wearable inertial sensor to measure velocity and power in the back squat and bench press (2018)
Journal Article
Orange, S. T., Metcalfe, J. W., Liefeith, A., Marshall, P., Madden, L. A., Fewster, C. R., & Vince, R. V. (2019). Validity and reliability of a wearable inertial sensor to measure velocity and power in the back squat and bench press. Journal of strength and conditioning research, 33(9), 2398-2408. https://doi.org/10.1519/JSC.0000000000002574

Orange, ST, Metcalfe, JW, Liefeith, A, Marshall, P, Madden, LA, Fewster, CR, and Vince, RV. Validity and reliability of a wearable inertial sensor to measure velocity and power in the back squat and bench press. J Strength Cond Res 33(9): 2398-2408,... Read More about Validity and reliability of a wearable inertial sensor to measure velocity and power in the back squat and bench press.

Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults (2018)
Journal Article
Orange, S. T., Marshall, P., Madden, L. A., & Vince, R. V. (2019). Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults. Journal of strength and conditioning research, 33(10), 2733-2742. https://doi.org/10.1519/JSC.0000000000002536

Orange, ST, Marshall, P, Madden, LA, and Vince, RV. Short-term training and detraining effects of supervised vs. unsupervised resistance exercise in aging adults. J Strength Cond Res 33(10): 2733-2742, 2019-This study compared the effects of a 4-week... Read More about Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults.

The effect of a simulated commercial flight environment with hypoxia and low humidity on clotting, platelet, and endothelial function in participants with type 2 diabetes - A cross-over study (2018)
Journal Article
Konya, J., Spurgeon, B. E. J., Al Qaissi, A., Sathyapalan, T., Ajjan, R., Madden, L., …Atkin, S. L. (2018). The effect of a simulated commercial flight environment with hypoxia and low humidity on clotting, platelet, and endothelial function in participants with type 2 diabetes - A cross-over study. Frontiers in endocrinology, 9(FEB), Article 26. https://doi.org/10.3389/fendo.2018.00026

© 2018 Konya, Al Qaissi, Sathyapalan, Ajjan, Madden, Naseem, Garrett, Kilpatrick and Atkin. Aims: To determine if clotting, platelet, and endothelial function were affected by simulated short-haul commercial air flight conditions (SF) in participants... Read More about The effect of a simulated commercial flight environment with hypoxia and low humidity on clotting, platelet, and endothelial function in participants with type 2 diabetes - A cross-over study.

Differing mechanisms of thrombin generation in live haematological and solid cancer cells determined by calibrated automated thrombography (2017)
Journal Article
Adesanya, M. A., Maraveyas, A., & Madden, L. (2017). Differing mechanisms of thrombin generation in live haematological and solid cancer cells determined by calibrated automated thrombography. Blood Coagulation and Fibrinolysis, 28(8), 602-611. https://doi.org/10.1097/mbc.0000000000000644

© 2017 Wolters Kluwer Health, Inc. All rights reserved. Calibrated automated thrombography (CAT) is emerging as a reliable tool for real-Time estimation of thrombin generation potential. There is a clinical need for knowledge about the pathways under... Read More about Differing mechanisms of thrombin generation in live haematological and solid cancer cells determined by calibrated automated thrombography.

Cancer microvesicles induce tissue factor-related procoagulant activity in endothelial cells in vitro (2017)
Journal Article
Adesanya, M. A., Maraveyas, A., & Madden, L. A. (2017). Cancer microvesicles induce tissue factor-related procoagulant activity in endothelial cells in vitro. Blood Coagulation and Fibrinolysis, 28(5), 365-372. https://doi.org/10.1097/MBC.0000000000000607

Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved. Microvesicles associated with tissue factor (TF) may play a role in cancer-related venous thromboembolism; however, not much is known about their interaction with the tumour stroma, es... Read More about Cancer microvesicles induce tissue factor-related procoagulant activity in endothelial cells in vitro.

The test-retest reliability of four functional mobility tests in apparently healthy adults (2016)
Journal Article
Northgraves, M. J., Hayes, S. C., Marshall, P., Madden, L. A., & Vince, R. V. (2016). The test-retest reliability of four functional mobility tests in apparently healthy adults. Isokinetics and Exercise Science, 24(3), 171-179. https://doi.org/10.3233/ies-160614

Background: Simple field tests are often used to assess functional mobility in clinical settings. Despite having many benefits, these tests are susceptible to measurement error and individual variation. Objectives: To examine the test-retest and abso... Read More about The test-retest reliability of four functional mobility tests in apparently healthy adults.

Duramycin-induced calcium release in cancer cells (2016)
Journal Article
Broughton, L. J., Crow, C., Madden, L. A., & Maraveyas, A. (2016). Duramycin-induced calcium release in cancer cells. Anti-cancer drugs, 27(3), 173-182. https://doi.org/10.1097/cad.0000000000000313

Introduction: Duramycin through binding with phosphatidylethanolamine (PE) has shown potential to be an effective anti-tumour agent. However its mode of action in relation to tumour cells is not fully understood. Methods: PE expression on the surface... Read More about Duramycin-induced calcium release in cancer cells.

Implications of a pre-exercise alkalosis-mediated attenuation of HSP72 on its response to a subsequent bout of exercise (2015)
Journal Article
Peart, D. J., Kirk, R. J., Madden, L. A., & Vince, R. V. (2016). Implications of a pre-exercise alkalosis-mediated attenuation of HSP72 on its response to a subsequent bout of exercise. Amino acids, 48(2), 499-504. https://doi.org/10.1007/s00726-015-2103-1

The aim of this study was to investigate if a pre-exercise alkalosis-mediated attenuation of HSP72 had any effect on the response of the same stress protein after a subsequent exercise. Seven physically active males [25.0 ± 6.5 years, 182.1 ± 6.0 cm,... Read More about Implications of a pre-exercise alkalosis-mediated attenuation of HSP72 on its response to a subsequent bout of exercise.

Repeated supra-maximal sprint cycling with and without sodium bicarbonate supplementation induces endothelial microparticle release (2013)
Journal Article
Kirk, R. J., Peart, D. J., Madden, L. A., & Vince, R. V. (2014). Repeated supra-maximal sprint cycling with and without sodium bicarbonate supplementation induces endothelial microparticle release. European journal of sport science : the official journal of the European College of Sport Science, 14(4), 345-352. https://doi.org/10.1080/17461391.2013.785600

Under normal homeostatic conditions, the endothelium releases microparticles (MP), which are known to increase under stressful conditions and in disease states. CD105 (endoglin) and CD106 (vascular cell adhesion molecule-1) are expressed on the surfa... Read More about Repeated supra-maximal sprint cycling with and without sodium bicarbonate supplementation induces endothelial microparticle release.

Photothermal colloid antibodies for shape-selective recognition and killing of microorganisms (2013)
Journal Article
Borovička, J., Metheringham, W. J., Madden, L. A., Walton, C. D., Stoyanov, S. D., & Paunov, V. N. (2013). Photothermal colloid antibodies for shape-selective recognition and killing of microorganisms. Journal of the American Chemical Society, 135(14), 5282-5285. https://doi.org/10.1021/ja400781f

We have developed a class of selective antimicrobial agents based on the recognition of the shape and size of the bacterial cells. These agents are anisotropic colloid particles fabricated as negative replicas of the target cells which involve templa... Read More about Photothermal colloid antibodies for shape-selective recognition and killing of microorganisms.

Increased inducible heat shock protein 72 expression associated with PBMC isolated from patients with haematological tumours (2012)
Journal Article
Madden, L. A., Hayman, Y. A., Underwood, C., Vince, R. V., Greenman, J., Allsup, D., & Ali, S. (2012). Increased inducible heat shock protein 72 expression associated with PBMC isolated from patients with haematological tumours. Scandinavian journal of clinical & laboratory investigation, 72(5), 380-386. https://doi.org/10.3109/00365513.2012.681683

Background. Heat shock protein 72 (Hsp72) is a highly inducible stress protein and molecular chaperone. Cancers have been shown to be associated with increased Hsp72 expression within the tumour itself and this may lead to resistance to apoptosis. Me... Read More about Increased inducible heat shock protein 72 expression associated with PBMC isolated from patients with haematological tumours.

Intraluminal thrombus has a selective influence on matrix metalloproteinases and their inhibitors (tissue inhibitors of matrix metalloproteinases) in the wall of abdominal aortic aneurysms (2012)
Journal Article
Abdul Rahman, M., Mazari, F., Khan, J. A., Madden, L., McCollum, P., Shahin, Y., …Smith, G. (2012). Intraluminal thrombus has a selective influence on matrix metalloproteinases and their inhibitors (tissue inhibitors of matrix metalloproteinases) in the wall of abdominal aortic aneurysms. Annals of vascular surgery, 26(3), 322-329. https://doi.org/10.1016/j.avsg.2011.08.015

BACKGROUND The influence of intraluminal thrombus (ILT) on the proteolytic environment within the wall of an abdominal aortic aneurysm (AAA) is unknown. This is the first study to examine the correlation between ILT thickness and the levels of matrix... Read More about Intraluminal thrombus has a selective influence on matrix metalloproteinases and their inhibitors (tissue inhibitors of matrix metalloproteinases) in the wall of abdominal aortic aneurysms.

Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup (2011)
Journal Article
Rodríguez-Villarreal, A. I., Tarn, M. D., Madden, L. A., Lutz, J. B., Greenman, J., Samitier, J., & Pamme, N. (2011). Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup. Lab on a chip, 11(7), 1240-1248. https://doi.org/10.1039/c0lc00464b

The continuous flow focussing and manipulation of particles and cells are important factors in microfluidic applications for performing accurate and reproducible procedures downstream. Many particle focussing methods require complex setups or channel... Read More about Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup.

Identification of methicillin-resistant Staphylococcus aureus-specific peptides for targeted photoantimicrobial chemotherapy (2011)
Journal Article
Vince, R. V., Madden, L. A., Alonso, C. M., Savoie, H., Boyle, R. W., Todman, M., …Greenman, J. (2011). Identification of methicillin-resistant Staphylococcus aureus-specific peptides for targeted photoantimicrobial chemotherapy. Photochemical & photobiological sciences : an international journal, 10(4), 515-522. https://doi.org/10.1039/c0pp00267d

The increasing prevalence of multi-drug resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), necessitates development of alternative modes of bacterial targeting which are not hindered by antibiotic resistance and minimise... Read More about Identification of methicillin-resistant Staphylococcus aureus-specific peptides for targeted photoantimicrobial chemotherapy.

The effect of hyperbaric oxygen preconditioning on heat shock protein 72 expression following in vitro stress in human monocytes (2010)
Journal Article
Vince, R. V., Midgley, A. W., Laden, G., & Madden, L. A. (2011). The effect of hyperbaric oxygen preconditioning on heat shock protein 72 expression following in vitro stress in human monocytes. Cell Stress and Chaperones, 16(3), 339-343. https://doi.org/10.1007/s12192-010-0246-2

Hyperbaric oxygen (HBO) is thought to confer protection to cells via a cellular response to free radicals. This process may involve increased expression of heat shock proteins, in particular the highly inducible heat shock protein 72 (Hsp72). Healthy... Read More about The effect of hyperbaric oxygen preconditioning on heat shock protein 72 expression following in vitro stress in human monocytes.

Viability of plant spore exine capsules for microencapsulation (2010)
Journal Article
Barrier, S., Diego-Taboada, A., Thomasson, M. J., Madden, L., Pointon, J. C., Wadhawan, J. D., …Mackenzie, G. (2011). Viability of plant spore exine capsules for microencapsulation. Journal of Materials Chemistry, 21(4), 975-981. https://doi.org/10.1039/c0jm02246b

Sporopollenin exine capsules (SECs) (outer exoskeletal wall of the spores of Lycopodium clavatum) were extracted and examined for their potential use as microcapsules. They were shown, by laser scanning confocal microscopy (LSCM), to be void of their... Read More about Viability of plant spore exine capsules for microencapsulation.