All Outputs (205)

Biomechanical evaluation of the unilateral crossbite on the asymmetrical development of the craniofacial complex. A mechano-morphological approach (2022)
Journal Article
Ortún-Terrazas, J., Fagan, M. J., Cegoñino, J., Illipronti-Filho, E., & del Palomar, A. P. (2022). Biomechanical evaluation of the unilateral crossbite on the asymmetrical development of the craniofacial complex. A mechano-morphological approach. Computer Methods and Programs in Biomedicine, 217, Article 106703. https://doi.org/10.1016/j.cmpb.2022.106703

Background and Objective: The occlusion effect on the craniofacial development is a controversial topic that has attracted the interest of many researchers but that remains unclear, mainly due to the difficulties on measure its mechanical response ex... Read More about Biomechanical evaluation of the unilateral crossbite on the asymmetrical development of the craniofacial complex. A mechano-morphological approach.

Modeling and control of anterior–posterior and medial–lateral sways in standing posture (2022)
Journal Article
Hou, M., Fagan, M., Vanicek, N., & Dobson, C. A. (2022). Modeling and control of anterior–posterior and medial–lateral sways in standing posture. Journal of biomechanics, 134, Article 110930. https://doi.org/10.1016/j.jbiomech.2021.110930

To study essential anterior–posterior and medial–lateral sways of the stance caused by rotational movements about the ankle and hip joints, a mathematical model is developed for the 3D postural kinematics and dynamics. The model is in the form of non... Read More about Modeling and control of anterior–posterior and medial–lateral sways in standing posture.

Assessments of bilateral asymmetry with application in human skull analysis (2021)
Journal Article
Hou, M., & Fagan, M. J. (2021). Assessments of bilateral asymmetry with application in human skull analysis. PLoS ONE, 16(10), Article e0258146. https://doi.org/10.1371/journal.pone.0258146

As a common feature, bilateral symmetry of biological forms is ubiquitous, but in fact rarely exact. In a setting of analytic geometry, bilateral symmetry is defined with respect to a point, line or plane, and the well-known notions of fluctuating as... Read More about Assessments of bilateral asymmetry with application in human skull analysis.

From micro to macroevolution: drivers of shape variation in an island radiation of Podarcis lizards (2021)
Journal Article
Taverne, M., Dutel, H., Fagan, M., Štambuk, A., Lisičić, D., Tadić, Z., Fabre, A. C., & Herrel, A. (2021). From micro to macroevolution: drivers of shape variation in an island radiation of Podarcis lizards. Evolution, 75(11), 2685-2707. https://doi.org/10.1111/evo.14326

Phenotypictraits have been shown to evolve in response to variation in the environment. However, the evolutionary processes underlying the emergence of phenotypic diversity can typically only be understood at the population level. Consequently, how s... Read More about From micro to macroevolution: drivers of shape variation in an island radiation of Podarcis lizards.

Back to the bones: do muscle area assessment techniques predict functional evolution across a macroevolutionary radiation? (2021)
Journal Article
Bates, K. T., Wang, L., Dempsey, M., Broyde, S., Fagan, M. J., & Cox, P. G. (2021). Back to the bones: do muscle area assessment techniques predict functional evolution across a macroevolutionary radiation?. Interface, 18(180), Article 20210324. https://doi.org/10.1098/rsif.2021.0324

Measures of attachment or accommodation area on the skeleton are a popular means of rapidly generating estimates of muscle proportions and functional performance for use in large-scale macroevolutionary studies. Herein, we provide the first evaluatio... Read More about Back to the bones: do muscle area assessment techniques predict functional evolution across a macroevolutionary radiation?.

Computational biomechanical modelling of the rabbit cranium during mastication (2021)
Journal Article
Watson, P. J., Sharp, A. C., Choudhary, T., Fagan, M. J., Dutel, H., Evans, S. E., & Gröning, F. (2021). Computational biomechanical modelling of the rabbit cranium during mastication. Scientific reports, 11(1), https://doi.org/10.1038/s41598-021-92558-5

Although a functional relationship between bone structure and mastication has been shown in some regions of the rabbit skull, the biomechanics of the whole cranium during mastication have yet to be fully explored. In terms of cranial biomechanics, th... Read More about Computational biomechanical modelling of the rabbit cranium during mastication.

Regional patterning in tail vertebral form and function in chameleons (Chamaeleo calyptratus) (2021)
Journal Article
Luger, A. M., Watson, P. J., Dutel, H., Fagan, M. J., Van Hoorebeke, L., Herrel, A., & Adriaens, D. (2021). Regional patterning in tail vertebral form and function in chameleons (Chamaeleo calyptratus). Integrative and Comparative Biology, 61(2), 455-463. https://doi.org/10.1093/icb/icab125

Previous studies have focused on documenting shape variation in the caudal vertebrae in chameleons underlying prehensile tail function. The goal of this study was to test the impact of this variation on tail function using multibody dynamic analysis... Read More about Regional patterning in tail vertebral form and function in chameleons (Chamaeleo calyptratus).

Morphological variation of the hemophilic talus (2021)
Journal Article
Talbott, H. G., Wilkins, R. A., Redmond, A. C., Brockett, C. L., & Mengoni, M. (2021). Morphological variation of the hemophilic talus. Clinical Anatomy, 34(6), 941-947. https://doi.org/10.1002/ca.23757

Flattening of the trochlear tali is clinically observed as structural and functional changes advance in patients with hemarthropathy of the ankle. However, the degree of this flattening has not yet been quantified, and distribution of the morphologic... Read More about Morphological variation of the hemophilic talus.

Correction to: Evolutionary biomechanics: Hard tissues and soft evidence? (Proc. R. Soc. B (2021) 288 (20202809) DOI: 10.1098/rspb.2020.2809) (2021)
Journal Article
Broyde, S., Dempsey, M., Wang, L., Cox, P. G., Fagan, M., & Bates, K. T. (2021). Correction to: Evolutionary biomechanics: Hard tissues and soft evidence? (Proc. R. Soc. B (2021) 288 (20202809) DOI: 10.1098/rspb.2020.2809). Proceedings of the Royal Society B: Biological Sciences, 288(1950), Article 20202809. https://doi.org/10.1098/rspb.2021.0831

Further analysis of our finite element (FE) models, as part of ongoing work, has revealed a systematic error running through all 30 models in our original analysis. In all 30 FE models, the force magnitudes applied to represent maximum isometric cont... Read More about Correction to: Evolutionary biomechanics: Hard tissues and soft evidence? (Proc. R. Soc. B (2021) 288 (20202809) DOI: 10.1098/rspb.2020.2809).

Comparative cranial biomechanics in two lizard species: impact of variation in cranial design (2021)
Journal Article
Groning, F., Dutel, H., Gröning, F., Sharp, A. C., Watson, P. J., Herrel, A., Ross, C. F., Jones, M. E. H., Evans, S. E., & Fagan, M. J. (2021). Comparative cranial biomechanics in two lizard species: impact of variation in cranial design. The journal of experimental biology, 224(5), Article jeb.234831. https://doi.org/10.1242/jeb.234831

Cranial morphology in lepidosaurs is highly disparate and characterised by the frequent loss or reduction of bony elements. In varanids and geckos, the loss of the postorbital bar is associated with changes in skull shape, but the mechanical principl... Read More about Comparative cranial biomechanics in two lizard species: impact of variation in cranial design.

Evolutionary biomechanics: hard tissues and soft evidence? (2021)
Journal Article
Broyde, S., Dempsey, M., Wang, L., Cox, P. G., Fagan, M., & Bates, K. T. (2021). Evolutionary biomechanics: hard tissues and soft evidence?. Proceedings of the Royal Society B: Biological Sciences, 288(1945), Article 20202809. https://doi.org/10.1098/rspb.2020.2809

Biomechanical modelling is a powerful tool for quantifying the evolution of functional performance in extinct animals to understand key anatomical innovations and selective pressures driving major evolutionary radiations. However, the fossil record i... Read More about Evolutionary biomechanics: hard tissues and soft evidence?.

Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading (2020)
Presentation / Conference Contribution
Moetazedian, A., Gleadall, A., Mele, E., & Silberschmidt, V. V. (2020, June). Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading. Presented at 1st Virtual European Conference on Fracture, Online

With a general cautious attitude regarding the anisotropic properties of upright 3D-printed parts, there is a lack of fundamental understanding of behavior of 3D-printed polymers under cyclic loading condition, which is more representative of real-li... Read More about Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading.

The biomechanical role of the chondrocranium and the material properties of cartilage (2020)
Journal Article
Jones, M. E. H., Gröning, F., Aspden, R. M., Dutel, H., Sharp, A., Moazen, M., Fagan, M. J., & Evans, S. E. (2020). The biomechanical role of the chondrocranium and the material properties of cartilage. Vertebrate Zoology, 70(4), 699-715. https://doi.org/10.26049/VZ70-4-2020-10

The chondrocranium is the cartilage component of the vertebrate braincase. Among jawed vertebrates it varies greatly in structure, mineralisation, and in the extent to which it is replaced by bone during development. In mammals, birds, and some bony... Read More about The biomechanical role of the chondrocranium and the material properties of cartilage.

Viscoelastically active sutures – A stitch in time? (2020)
Journal Article
France, L. A., & Fancey, K. S. (2021). Viscoelastically active sutures – A stitch in time?. Materials Science and Engineering: C, 121, Article 111695. https://doi.org/10.1016/j.msec.2020.111695

We present results to show that a commercially available polypropylene suture filament (Ethicon Prolene), following annealing and tensile creep can, after creep load removal, release viscoelastically stored energy over a period of several weeks. Spec... Read More about Viscoelastically active sutures – A stitch in time?.

Mathematical modeling of canonical and non-canonical NF-κB pathways in TNF stimulation (2020)
Journal Article
Ji, B., Zhang, Y., Zhen, C., Fagan, M. J., & Yang, Q. (2020). Mathematical modeling of canonical and non-canonical NF-κB pathways in TNF stimulation. Computer Methods and Programs in Biomedicine, 196, Article 105677. https://doi.org/10.1016/j.cmpb.2020.105677

Background and objective: NF-κB can be activated by the canonical and non-canonical pathways. These two pathways interplay via the TRAF1|NIK complex after stimulation by TNF. However existing mathematical models of two pathways are inadequate. In thi... Read More about Mathematical modeling of canonical and non-canonical NF-κB pathways in TNF stimulation.

Multi-beat averaging reveals u waves are ubiquitous and standing tall at elevated heart rates following exercise (2020)
Journal Article
Al-Karadi, M. S., & Langley, P. (2020). Multi-beat averaging reveals u waves are ubiquitous and standing tall at elevated heart rates following exercise. Sensors, 20(14), 1-12. https://doi.org/10.3390/s20144029

The reporting of U wave abnormalities is clinically important, but the measurement of this small electrocardiographic (ECG) feature is extremely difficult, especially in challenging recording conditions, such as stress exercise, due to contaminating... Read More about Multi-beat averaging reveals u waves are ubiquitous and standing tall at elevated heart rates following exercise.

The influence of musculoskeletal forces on the growth of the prenatal cortex in the ilium: a finite element study (2020)
Journal Article
Watson, P. J., Fagan, M. J., & Dobson, C. A. (in press). The influence of musculoskeletal forces on the growth of the prenatal cortex in the ilium: a finite element study. Computer methods in biomechanics and biomedical engineering, https://doi.org/10.1080/10255842.2020.1777546

Remodelling and adaptation of bone within the pelvis is believed to be influenced by the mechanical strains generated during locomotion. Variation in the cortical bone thickness observed in the prenatal ilium has been linked to the musculoskeletal lo... Read More about The influence of musculoskeletal forces on the growth of the prenatal cortex in the ilium: a finite element study.

Towards an early 3D-diagnosis of craniofacial asymmetry by computing the accurate midplane: A PCA-based method (2020)
Journal Article
Ortún-Terrazas, J., Fagan, M. J., Cegoñino, J., Illipronti-Filho, E., & Pérez del Palomar, A. (2020). Towards an early 3D-diagnosis of craniofacial asymmetry by computing the accurate midplane: A PCA-based method. Computer Methods and Programs in Biomedicine, 191, Article 105397. https://doi.org/10.1016/j.cmpb.2020.105397

Background and objective: Craniofacial asymmetry is a common growth disorder often caused by unilateral chewing. Although an early orthodontic treatment would avoid surgical procedures later in life, the uncertainty of defining the accurate sagittal... Read More about Towards an early 3D-diagnosis of craniofacial asymmetry by computing the accurate midplane: A PCA-based method.

P014 | THE INFLUENCE OF SUBCHONDRAL BONE CYSTS ON TISSUE PRESSURES IN THE TIBIOTALAR JOINT (2020)
Presentation / Conference Contribution
Talbott, H., Wilkins, R., Redmond, A., Brockett, C., & Mengoni, M. P014 | THE INFLUENCE OF SUBCHONDRAL BONE CYSTS ON TISSUE PRESSURES IN THE TIBIOTALAR JOINT. Presented at 13th Annual Congress of European Association for Haemophilia and Allied Disorders 2020, 5–7 February 2020, The Hague, The Netherlands

Introduction: Subchondral bone cysts are an indicator of late stage
haemophilic joint disease (HJD); however, the implication of these
cysts on joint health is little understood. The aim of this study was
to assess, computationally, the influence... Read More about P014 | THE INFLUENCE OF SUBCHONDRAL BONE CYSTS ON TISSUE PRESSURES IN THE TIBIOTALAR JOINT.

Galaxy and Mass Assembly (GAMA): Defining passive galaxy samples and searching for the UV upturn (2019)
Journal Article
Phillipps, S., Ali, S. S., Bremer, M. N., de Propris, R., Sansom, A. E., Cluver, M. E., Alpaslan, M., Brough, S., Brown, M. J., Davies, L. J., Driver, S. P., Grootes, M. W., Holwerda, B. W., Hopkins, A. M., James, P. A., Pimbblet, K., Robotham, A. S., Taylor, E. N., & Wang, L. (2020). Galaxy and Mass Assembly (GAMA): Defining passive galaxy samples and searching for the UV upturn. Monthly notices of the Royal Astronomical Society, 492(2), 2128-2139. https://doi.org/10.1093/mnras/stz3552

© 2019 The Author(s) We use data from the GAMA and GALEX surveys to demonstrate that the UV upturn, an unexpected excess of ultraviolet flux from a hot stellar component, seen in the spectra of many early-type galaxies, arises from processes internal... Read More about Galaxy and Mass Assembly (GAMA): Defining passive galaxy samples and searching for the UV upturn.