Assessing the health economics of two home-based exercise programmes in obese adults Jun 1, 2018 - Dec 31, 2021
Obesity is a public health concern of epidemic proportions, increasing in prevalence across most demographics and increasingly younger ages (Ng et al., 2014) and is a risk factor for a myriad of other psychosocial, physiological, and musculoskeletal... Read More about Assessing the health economics of two home-based exercise programmes in obese adults.

Blood test for clinical therapy guidance of non-small cell lung cancer patients Jan 1, 2017 - Oct 31, 2022

TRANSFORM: Reducing Inequalities in Cancer Outcomes in Yorkshire: Realising our potential for innovation in Diagnosis, Patient Management, Survivorship and Palliative Care Research Sep 1, 2017 - Dec 31, 2026
The death rate is higher in Yorkshire than the rest of England resulting in about 200 extra deaths each year of which more than half are in Hull. There are other significant cancer outcome inequalities between different groups; for example poorer pe... Read More about TRANSFORM: Reducing Inequalities in Cancer Outcomes in Yorkshire: Realising our potential for innovation in Diagnosis, Patient Management, Survivorship and Palliative Care Research.

The role of bacteria in the skin: Cold atmospheric plasma for the treatment of pathological skin healing Apr 1, 2017 - Mar 31, 2020
Chronic wounds remain a major area of unmet clinical need, with infection a principle contributing factor to wound chronicity. This project builds upon strong preliminary data suggesting that healing outcome can be directly linked to both wound micro... Read More about The role of bacteria in the skin: Cold atmospheric plasma for the treatment of pathological skin healing.

MICA: The role of arginase in chronic delayed wound healing Aug 1, 2016 - Oct 17, 2017

FRAIL-HEART: Assessment of Frailty in Elderly People with Ischemic Heart Disease being considered for Revascularisation: An Observational study Apr 1, 2017 - Mar 31, 2020

Translational Research in the Molecular Imaging Research Centre Aug 1, 2016 - Jul 31, 2018

The effect of corticosteroids on the release of immune modulating factors from Graves’ disease tissue maintained using microfluidic culture. Jun 1, 2017 - May 31, 2018

LIPS: A prospective registry-based cohort study to monitor the diagnosis and management of acute leukaemia in pregnancy Jun 1, 2018 - Feb 28, 2022

New technology to improve capability for clinical radiopharmaceutical production Jan 1, 2019 - Feb 28, 2022
Medical imaging techniques rely on radioactive atoms that don't last for a long time and so methods need to be developed to handle them on hospital sites or close by. Essentially this is drug factory near to the patient as the material is decaying al... Read More about New technology to improve capability for clinical radiopharmaceutical production.

A study of the incorporation and release of tissue factor as cancer cell-derived microparticles. Aug 1, 2014 - Jul 31, 2017

CLL Research Jan 26, 2015 - Dec 31, 2025
Translational research project utilising prospective sample collection from patients attending the Haematology Clinic, Hull university Teaching Hospital Trust, to facilitate research within the University of Hull.

Can prevention of the activation of PAR2 prevent the release of procoagulant microvesicles from cancer cells, reduce the risk of VTE and contain the deterioration of the vasculature? Jul 1, 2015 - Jun 30, 2020
The study aims to demonstrate the indirect effect of Apixaban on suppressing the release of pro-inflammatory, pro-coagulant tissue factor-containing microvesicles, by inhibiting factor Xa and preventing the activation of PAR2. The study also demonstr... Read More about Can prevention of the activation of PAR2 prevent the release of procoagulant microvesicles from cancer cells, reduce the risk of VTE and contain the deterioration of the vasculature?.

Development of a multipurpose small animal phantom for pre-clinical radiotherapy studies Apr 1, 2016 - Mar 31, 2019
The project aims to both reduce the total number of animals used for preclinical radiotherapy experiments whilst concurrently increasing the accuracy of such investigations in order to maximise their clinical impact. This will be achieved through the... Read More about Development of a multipurpose small animal phantom for pre-clinical radiotherapy studies.

Positron Emission Tomography research Mar 1, 2016 - Feb 28, 2017

The Hull-Norwich Gut-Brian Study May 31, 2016 - Jun 30, 2018
Objective To obtain mechanistic insights into how resident commensal gut bacteria (the microbiota) influences host physiology and in particular brain function and host behaviour. The focus is on identifying the pathways and molecules originating from... Read More about The Hull-Norwich Gut-Brian Study.

Lab on a Chip NC3Rs Engagement Award Aug 15, 2016 - Aug 14, 2017
This project will deliver a programme of public engagement with innovative hands-on activities in the area of tissue/organ-on-a-chip which are emerging as life-like models to reduce and replace animal testing to school children and the general public... Read More about Lab on a Chip NC3Rs Engagement Award.

ISCHEMIA: Internation Study of Comparative Health Effectiveness with Medical and Invasive Approaches Apr 15, 2013 - Jun 30, 2019
Primary objective is to determine whether an invasive (INV) strategy of routine early cardiac catheterization with intent for optimal revascularization in addition to optimal medical therapy in patients with stable ischemic heart disease (SIHD) and a... Read More about ISCHEMIA: Internation Study of Comparative Health Effectiveness with Medical and Invasive Approaches.

Training scientists to develop and Image materials for Tissue Engineering and Regenerative Medicine (iTERM) Oct 1, 2013 - Sep 30, 2017
With an increasingly aging population, new treatment solutions for diseased, defective, or damaged tissues need to be developed. Although human donor material would be preferable for these purposes, this is often not available and often associated wi... Read More about Training scientists to develop and Image materials for Tissue Engineering and Regenerative Medicine (iTERM).

In vitro analysis of thyroid cancer and it's response to radiotherapy May 22, 2015 - May 21, 2018