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Outputs (3838)

Domiciliary Cough Monitoring for the Prediction of COPD Exacerbations (2021)
Journal Article
Crooks, M. G., den Brinker, A. C., Thackray-Nocera, S., van Dinther, R., Wright, C. E., & Morice, A. H. (2021). Domiciliary Cough Monitoring for the Prediction of COPD Exacerbations. Lung, 199(2), 131-137. https://doi.org/10.1007/s00408-021-00435-9

Introduction: Acute exacerbations of COPD (AE-COPD) are a leading cause of health service utilisation and are associated with morbidity and mortality. Identifying the prodrome of AE-COPD by monitoring symptoms and physiological parameters (telemonito... Read More about Domiciliary Cough Monitoring for the Prediction of COPD Exacerbations.

Physiotherapists’ views on their role in self-management approaches: A qualitative systematic review (2021)
Journal Article
Killingback, C., Thompson, M., Chipperfield, S., Clark, C., & Williams, J. (in press). Physiotherapists’ views on their role in self-management approaches: A qualitative systematic review. Physiotherapy theory and practice, 1-15. https://doi.org/10.1080/09593985.2021.1911011

Background: Self-management has been an increasingly important aspect of helping people manage their long-term conditions. The aim of this qualitative review was to synthesize the views of physiotherapists concerning their delivery of a self-manageme... Read More about Physiotherapists’ views on their role in self-management approaches: A qualitative systematic review.

Inter-rater reliability of care home staff's proxy judgements with residents' assessments of their own health-related quality of life: an analysis of the PATCH trial EQ-5D data (2021)
Journal Article
Kelly, C., Hulme, C., Graham, L., Ellwood, A., Patel, I., Cundill, B., Farrin, A., Goodwin, M., Hull, K., Fisher, J., & Forster, A. (2021). Inter-rater reliability of care home staff's proxy judgements with residents' assessments of their own health-related quality of life: an analysis of the PATCH trial EQ-5D data. Age and ageing, 50(4), 1314-1320. https://doi.org/10.1093/ageing/afab053

OBJECTIVES: to compare care staff proxies with care home residents' self-assessment of their health-related quality of life (HRQoL). METHODS: we assessed the degree of inter-rater reliability between residents and care staff proxies for the EQ-5D-5L... Read More about Inter-rater reliability of care home staff's proxy judgements with residents' assessments of their own health-related quality of life: an analysis of the PATCH trial EQ-5D data.

Monitoring practices of training load and biological maturity in UK soccer academies (2021)
Journal Article
Salter, J., De Ste Croix, M. B., Hughes, J., Weston, M., & Towlson, C. (2021). Monitoring practices of training load and biological maturity in UK soccer academies. International journal of sports physiology and performance : IJSPP, 16(3), 395-406. https://doi.org/10.1123/IJSPP.2019-0624

Purpose: Overuse injury risk increases during periods of accelerated growth, which can subsequently impact development in academy soccer, suggesting a need to quantify training exposure. Nonprescriptive development scheme legislation could lead to in... Read More about Monitoring practices of training load and biological maturity in UK soccer academies.

Understanding the impact of professional motivation on the workforce crisis in medicine: a rapid review (2021)
Journal Article
Andah, E., Essang, B., Friend, C., Greenley, S., Harvey, K., Spears, M., & Reeve, J. (2021). Understanding the impact of professional motivation on the workforce crisis in medicine: a rapid review. BJGP Open, 5(2), 1-11. https://doi.org/10.3399/BJGPO.2021.0005

Background: The NHS is facing a workforce crisis. Responses to date have focused on improving recruitment of staff, but less attention has been paid to retention. Aim: To conduct a rapid review using Rosabeth Moss Kanter's three Ms model of workforce... Read More about Understanding the impact of professional motivation on the workforce crisis in medicine: a rapid review.

Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells (2021)
Journal Article
Kirkham, F., Pera, A., Simanek, A. M., Bano, A., Morrow, G., Reus, B., Caserta, S., Smith, H. E., Davies, K. A., Rajkumar, C., & Kern, F. (in press). Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells. Theranostics, 11(12), 5728-5741. https://doi.org/10.7150/thno.58356

Human Cytomegalovirus (CMV) infection is associated with atherosclerosis, higher cardiovascular disease (CVD) risk, and an increase in memory T-cells (Tmem). T-cells have also been implicated in CVD, independently of CMV infection. To better understa... Read More about Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells.

Prognostic predictors relevant to end-of-life palliative care in Parkinson's disease and related disorders: A systematic review (2021)
Journal Article
Akbar, U., McQueen, R. B., Bemski, J., Carter, J., Goy, E. R., Kutner, J., Johnson, M. J., Miyasaki, J. M., & Kluger, B. (2021). Prognostic predictors relevant to end-of-life palliative care in Parkinson's disease and related disorders: A systematic review. Journal of Neurology, Neurosurgery and Psychiatry, 92(6), 629-636. https://doi.org/10.1136/jnnp-2020-323939

Parkinson's disease and related disorders (PDRD) are the second most common neurodegenerative disease and a leading cause of death. However, patients with PDRD receive less end-of-life palliative care (hospice) than other illnesses, including other n... Read More about Prognostic predictors relevant to end-of-life palliative care in Parkinson's disease and related disorders: A systematic review.

The experience of delirium in palliative care settings for patients, family, clinicians and volunteers: A qualitative systematic review and thematic synthesis (2021)
Journal Article
Featherstone, I., Hosie, A., Siddiqi, N., Grassau, P., Bush, S. H., Taylor, J., Sheldon, T., & Johnson, M. J. (2021). The experience of delirium in palliative care settings for patients, family, clinicians and volunteers: A qualitative systematic review and thematic synthesis. Palliative medicine, 35(6), 988-1004. https://doi.org/10.1177/02692163211006313

Background: Delirium is common in palliative care settings and is distressing for patients, their families and clinicians. To develop effective interventions, we need first to understand current delirium care in this setting. Aim: To understand patie... Read More about The experience of delirium in palliative care settings for patients, family, clinicians and volunteers: A qualitative systematic review and thematic synthesis.

aDolescents gEnder surVey, rEsponsible coupLes evaluatiOn, and capacity building Project in India (DEVELOP): a study protocol [version 2; peer review: 2 approved] (2021)
Journal Article
Ahankari, A., Hayter, M., Whitfield, C., Ali, P., Giridhari, S., Tambe, S., Kabra, P., Rayamane, K., & Ovseiko, P. (2021). aDolescents gEnder surVey, rEsponsible coupLes evaluatiOn, and capacity building Project in India (DEVELOP): a study protocol [version 2; peer review: 2 approved]. F1000Research, 8, Article 958. https://doi.org/10.12688/f1000research.19521.2

Domestic violence and assault (DVA) against women is a serious concern in India. This affects the health and wellbeing of victims and their dependents. Published evidence has documented a variety of reasons for such violence in Indian societies, pavi... Read More about aDolescents gEnder surVey, rEsponsible coupLes evaluatiOn, and capacity building Project in India (DEVELOP): a study protocol [version 2; peer review: 2 approved].

Quantifying technical actions in professional soccer using foot-mounted inertial measurement units (2021)
Journal Article
Marris, J., Barrett, S., Abt, G., & Towlson, C. (2021). Quantifying technical actions in professional soccer using foot-mounted inertial measurement units. Science and Medicine in Football, https://doi.org/10.1080/24733938.2021.1910333

Objectives: This study aimed to (i) establish the concurrent validity and intra-unit reliability of a foot-mounted inertial measurement unit for monitoring soccer technical actions, (ii) quantify the within-microcycle inter-positional differences in... Read More about Quantifying technical actions in professional soccer using foot-mounted inertial measurement units.

‘Necessity is the mother of invention’: Specialist palliative care service innovation and practice change in response to COVID-19. Results from a multinational survey (CovPall) (2021)
Journal Article
Dunleavy, L., Preston, N., Bajwah, S., Bradshaw, A., Cripps, R., Fraser, L. K., Maddocks, M., Hocaoglu, M., Murtagh, F. E., Oluyase, A. O., Sleeman, K. E., Higginson, I. J., & Walshe, C. (2021). ‘Necessity is the mother of invention’: Specialist palliative care service innovation and practice change in response to COVID-19. Results from a multinational survey (CovPall). Palliative medicine, 35(5), 814-829. https://doi.org/10.1177/02692163211000660

Background: Specialist palliative care services have a key role in a whole system response to COVID-19, a disease caused by the SARS-CoV-2 virus. There is a need to understand service response to share good practice and prepare for future care. Aim:... Read More about ‘Necessity is the mother of invention’: Specialist palliative care service innovation and practice change in response to COVID-19. Results from a multinational survey (CovPall).

Investigating oxygen transport efficiencies in precision-cut liver slice-based organ-on-a-chip devices (2021)
Journal Article
Christensen, M. G., Cawthorne, C., Dyer, C. E., Greenman, J., & Pamme, N. (2021). Investigating oxygen transport efficiencies in precision-cut liver slice-based organ-on-a-chip devices. Microfluidics and Nanofluidics, 25(4), Article 35. https://doi.org/10.1007/s10404-021-02434-x

Microfluidic ‘organ-on-a-chip’ devices hold great potential for better mimicking the continuous flow microenvironment experienced by tissue and cells in vivo, thereby ensuring realistic transport of nutrients and elimination of waste products. Howeve... Read More about Investigating oxygen transport efficiencies in precision-cut liver slice-based organ-on-a-chip devices.

Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19 (2021)
Journal Article
Moin, A. S. M., Sathyapalan, T., Diboun, I., Atkin, S. L., & Butler, A. E. (in press). Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19. Scientific reports, 11(1), Article 6428. https://doi.org/10.1038/s41598-021-85760-y

Hyperactivation of the immune system through obesity and diabetes may enhance infection severity complicated by Acute Respiratory Distress Syndrome (ARDS). The objective was to determine the circulatory biomarkers for macrophage activation at baselin... Read More about Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19.

Becoming parents by adoption: a systematic review (2021)
Journal Article
Long, T., Jones, C., Jomeen, J., & Martin, C. (2021). Becoming parents by adoption: a systematic review. Journal of Health Visiting, 9(3), 116–127. https://doi.org/10.12968/johv.2021.9.3.116

Background
Transition to parenthood (TP) for biological parents has been extensively explored in research, shaping healthcare service provision from pre-conception, birth and beyond. Adoptive parents are in a unique position. Despite growing number... Read More about Becoming parents by adoption: a systematic review.

STEPFORWARD study: a randomised controlled feasibility trial of a self-aligning prosthetic ankle-foot for older patients with vascular-related amputations (2021)
Journal Article
Vanicek, N., Coleman, E., Watson, J., Bell, K., Barnett, C., McDaid, C., Twiste, M., Jepson, F., Salawu, A., Harrison, D., & Mitchell, N. (2021). STEPFORWARD study: a randomised controlled feasibility trial of a self-aligning prosthetic ankle-foot for older patients with vascular-related amputations. BMJ open, 11(3), Article e045195. https://doi.org/10.1136/bmjopen-2020-045195

Objectives To determine the feasibility of conducting a full-scale randomised controlled trial (RCT) of the effectiveness and cost-effectiveness of a self-aligning prosthetic ankle-foot compared with a standard prosthetic ankle-foot.

Design Multic... Read More about STEPFORWARD study: a randomised controlled feasibility trial of a self-aligning prosthetic ankle-foot for older patients with vascular-related amputations.

Examining public knowledge, attitudes and perceptions towards palliative care: a mixed method sequential study (2021)
Journal Article
McIlfatrick, S., Slater, P., Beck, E., Bamidele, O., McCloskey, S., Carr, K., Muldrew, D., Hanna-Trainor, L., & Hasson, F. (2021). Examining public knowledge, attitudes and perceptions towards palliative care: a mixed method sequential study. BMC Palliative Care, 20(1), Article 44. https://doi.org/10.1186/s12904-021-00730-5

Background: Palliative care is recognised as a public health issue with the need for earlier integration in the wider healthcare system. However, research indicates that it continues to be accessed late in the course of an illness, public understandi... Read More about Examining public knowledge, attitudes and perceptions towards palliative care: a mixed method sequential study.

The irrational health beliefs scale and health behaviors in a non-clinical population (2021)
Journal Article
Pitel, L., & Ballová Mikušková, E. (in press). The irrational health beliefs scale and health behaviors in a non-clinical population. European Journal of Health Psychology, https://doi.org/10.1027/2512-8442/a000075

To date, there has been inconclusive evidence on the predictive ability of health-related cognitive distortion, as measured by the Irrational Health Belief Scale (IHBS), regarding health behaviors (HBs). The aims of our study were to provide a valida... Read More about The irrational health beliefs scale and health behaviors in a non-clinical population.

The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update (2021)
Journal Article
Navashenaq, J. G., Shabgah, A. G., Hedayati-Moghadam, M., Ariaee, N., Mohammadi, H., Hemmatzadeh, M., Azhdari, S., Jamialahmadi, T., Sathyapalan, T., & Sahebkar, A. (2021). The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update. Life Sciences, 269, https://doi.org/10.1016/j.lfs.2021.119083

© 2021 Rheumatoid arthritis (RA) is an autoimmune disease that generally affects the joints. In the late stages of the disease, it can be associated with several complications. Although the exact etiology of RA is unknown, various studies have been p... Read More about The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update.