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Projects (482)

STATIC: A Randomised Phase III Trial Comparing Continuous with Intermittent Treatment Strategies in Chronic Lymphocytic Leukaemia (CLL) Jan 1, 2021 - Mar 31, 2031
Chronic lymphocytic leukaemia (CLL) is a cancer that affects the blood and bone marrow. It tends to progress slowly, and is incurable. CLL is the most common leukaemia in adults. The first treatment for CLL is chemotherapy. This is usually given for... Read More about STATIC: A Randomised Phase III Trial Comparing Continuous with Intermittent Treatment Strategies in Chronic Lymphocytic Leukaemia (CLL).

Development and pilot of the “Living with Polycystic Ovary Syndrome (PCOS)” structured education programme Apr 1, 2019 - Sep 30, 2021
Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive age group females and it is associated with various clinical features including irregular periods, male-pattern hair loss from the head and excess hair in other b... Read More about Development and pilot of the “Living with Polycystic Ovary Syndrome (PCOS)” structured education programme.

Partners in Practice Sep 23, 2019 - Mar 31, 2022
The East Riding of Yorkshire Council (ERYC) Partners in Practice (PiP) programme is part of a Department for Education funded initiative aimed at improving outcomes for children, young people and their families known to social care services by ensuri... Read More about Partners in Practice.

AZD9977: A Phase I, Open Label, Randomized, Parallel group, Multicentre study to Compare the Effect of AZD9977 and Spironolactone on Serum Potassium [sK+] during 28 days in Patients with HFmrEF or HFpEF and eGFR in the range of ≥40 and ≤70 mL/min/1.73m2 Feb 1, 2019 - Jan 31, 2020
A Phase I, Open Label, Randomized, Parallel group, Multicentre study to Compare the Effect of AZD9977 and Spironolactone on Serum Potassium [sK+] during 28 days in Patients with HFmrEF or HFpEF
and eGFR in the range of ≥40 and ≤70 mL/min/1.73m2.

PROMS: CPR Cancer outcomes: The use of comprehensive patient records (CPR) to define the impact of cancer, co-morbidities and late effects on individuals and the health service Sep 30, 2015 - Jun 30, 2019
The ageing population and increasing success of cancer services has resulted in more people living for long periods with and beyond a diagnosis of cancer. Whilst we know that many people living beyond a cancer diagnosis report unmet needs, there is i... Read More about PROMS: CPR Cancer outcomes: The use of comprehensive patient records (CPR) to define the impact of cancer, co-morbidities and late effects on individuals and the health service.

Novel dual CXCR4/CXCR7 receptor drugs: targeting secondary disease progression and resistance to immunotherapy in breast cancer Aug 1, 2019 - Jul 31, 2023
CXCR4/CXCR7-CXCL12 chemokine axis plays a pivotal role in breast cancer (BC) growth, survival, therapy evasion and metastasis. Clinically overexpression of CXCR4/CXCR7-CXCL12 correlates with aggressive BC disease and poor outcome. Evidence suggests c... Read More about Novel dual CXCR4/CXCR7 receptor drugs: targeting secondary disease progression and resistance to immunotherapy in breast cancer.

I3: Building Critical Mass, Increasing Scale and Impact for Palliative Care through International Collaboration Aug 1, 2019 - Mar 31, 2025
The world population is ageing and, with the growth of multi-morbidities, UK deaths are expected to increase by 40% by 2040. New models of care and treatments are urgently needed to improve quality of life for the significantly increased numbers of p... Read More about I3: Building Critical Mass, Increasing Scale and Impact for Palliative Care through International Collaboration.