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Encouraging use of community-based resources by bioscience students (2010)
Journal Article
Goulder, R., & Scott, G. W. (2010). Encouraging use of community-based resources by bioscience students. Bioscience education e-journal BEE-j, 16(1), 1-4. https://doi.org/10.3108/beej.16.c1

This communication reports how bioscience students are encouraged to benefit from city and regional community-based resources through use of a guidebook and student-managed learning. Positive outcomes of the module are that bioscience students take t... Read More about Encouraging use of community-based resources by bioscience students.

Targeted epidermal growth factor receptor therapy in malignant pleural mesothelioma: where do we stand? (2010)
Journal Article
Agarwal, V., Lind, M. J., & Cawkwell, L. (2011). Targeted epidermal growth factor receptor therapy in malignant pleural mesothelioma: where do we stand?. Cancer Treatment Reviews, 37(7), 533-542. https://doi.org/10.1016/j.ctrv.2010.11.004

The median survival for patients with malignant pleural mesothelioma remains extremely poor and there is a need for the development of more effective treatment modalities. The epidermal growth factor receptor is frequently over-expressed in malignant... Read More about Targeted epidermal growth factor receptor therapy in malignant pleural mesothelioma: where do we stand?.

Chronic lymphocytic leukaemia is a risk factor for venous thromboembolism (2010)
Journal Article
Whittle, A. M., Allsup, D. J., & Bailey, J. R. (2011). Chronic lymphocytic leukaemia is a risk factor for venous thromboembolism. Leukemia Research, 35(3), 419-421. https://doi.org/10.1016/j.leukres.2010.11.011

Venous thromboembolism (VTE) is a major cause of morbidity and mortality in cancer patients. The literature is sparse on the incidence in the most common lymphoid malignancy, chronic lymphocytic leukaemia (CLL). We calculated the incidence rates for... Read More about Chronic lymphocytic leukaemia is a risk factor for venous thromboembolism.

The effect of hyperbaric oxygen preconditioning on heat shock protein 72 expression following in vitro stress in human monocytes (2010)
Journal Article
Vince, R. V., Midgley, A. W., Laden, G., & Madden, L. A. (2011). The effect of hyperbaric oxygen preconditioning on heat shock protein 72 expression following in vitro stress in human monocytes. Cell Stress and Chaperones, 16(3), 339-343. https://doi.org/10.1007/s12192-010-0246-2

Hyperbaric oxygen (HBO) is thought to confer protection to cells via a cellular response to free radicals. This process may involve increased expression of heat shock proteins, in particular the highly inducible heat shock protein 72 (Hsp72). Healthy... Read More about The effect of hyperbaric oxygen preconditioning on heat shock protein 72 expression following in vitro stress in human monocytes.

The Ras related GTPase Miro is not required for mitochondrial transport in Dictyostelium discoideum (2010)
Journal Article
Vlahou, G., Eliáš, M., von Kleist-Retzow, J.-C., Wiesner, R. J., & Rivero, F. (2011). The Ras related GTPase Miro is not required for mitochondrial transport in Dictyostelium discoideum. European journal of cell biology, 90(4), 342-355. https://doi.org/10.1016/j.ejcb.2010.10.012

Ras-related GTPases of the Miro family have been implicated in mitochondrial homeostasis and microtubule-dependent transport. They consist of two GTP-binding domains separated by calcium-binding motifs and of a C-terminal transmembrane domain that ta... Read More about The Ras related GTPase Miro is not required for mitochondrial transport in Dictyostelium discoideum.

Polymorphic variation within the VWF gene contributes to the failure to detect mutations in patients historically diagnosed with type 1 von willebrand disease from the MCMDM-1VWD cohort (2010)
Journal Article
Hampshire, D. J., Burghel, G. J., Goudem, J., Bouvet, L. C., Eikenboom, J. C., Schneppenheim, R., Budde, U., Peake, I. R., & Goodeve, C. (2010). Polymorphic variation within the VWF gene contributes to the failure to detect mutations in patients historically diagnosed with type 1 von willebrand disease from the MCMDM-1VWD cohort. Haematologica, 95(12), 2163-2165. https://doi.org/10.3324/haematol.2010.027177

Clinical indications for intravascular ultrasound imaging (2010)
Journal Article
Bourantas, C. V., Naka, K. K., Garg, S., Thackray, S., Papadopoulos, D., Alamgir, F. M., Hoye, A., & Michalis, L. K. (2010). Clinical indications for intravascular ultrasound imaging. Echocardiography, 27(10), 1282-1290. https://doi.org/10.1111/j.1540-8175.2010.01259.x

Intravascular ultrasound (IVUS) is a catheter-based imaging modality, which provides high resolution cross-sectional images of the coronary arteries. Unlike angiography, which displays only the opacified luminal silhouette, IVUS permits imaging of bo... Read More about Clinical indications for intravascular ultrasound imaging.

TRPA1 is activated by direct addition of cysteine residues to the N-hydroxysuccinyl esters of acrylic and cinnamic acids (2010)
Journal Article
Sadofsky, L. R., Boa, A. N., Maher, S. A., Birrell, M. A., Belvisi, M. G., & Morice, A. H. (2011). TRPA1 is activated by direct addition of cysteine residues to the N-hydroxysuccinyl esters of acrylic and cinnamic acids. Pharmacological research : the official journal of the Italian Pharmacological Society, 63(1), 30-36. https://doi.org/10.1016/j.phrs.2010.11.004

The nociceptor TRPA1 is thought to be activated through covalent modification of specific cysteine residues on the N terminal of the channel. The precise mechanism of covalent modification with unsaturated carbonyl-containing compounds is unclear, th... Read More about TRPA1 is activated by direct addition of cysteine residues to the N-hydroxysuccinyl esters of acrylic and cinnamic acids.

Reduced functional avidity promotes central and effector memory CD4 T cell responses to tumor-associated antigens (2010)
Journal Article
Caserta, S., Kleczkowska, J., Mondino, A., & Zamoyska, R. (2010). Reduced functional avidity promotes central and effector memory CD4 T cell responses to tumor-associated antigens. Journal of Immunology, 185(11), 6545-6554. https://doi.org/10.4049/jimmunol.1001867

The effect of TCR signals on the differentiation of memory T cells is poorly defined. Conventional wisdom suggests that high-avidity interactions are best for the selection of vaccine Ag candidates or T cell specificities for adoptive T cell therapy... Read More about Reduced functional avidity promotes central and effector memory CD4 T cell responses to tumor-associated antigens.