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Positron detection in silica monoliths for miniaturised quality control of PET radiotracers

Tarn, Mark D.; Maneuski, Dzmitry; Alexander, Richard; Brown, Nathaniel J.; O’Shea, Val; Pimlott, Sally L.; Pamme, Nicole; Archibald, Stephen J.

Authors

Mark D. Tarn

Dzmitry Maneuski

Richard Alexander

Val O’Shea

Sally L. Pimlott



Abstract

We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [⁶⁸Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control. The system achieved a far superior signal-to-noise ratio compared to conventional sodium iodide-based radio-HPLC detection and allowed real-time visualisation of positrons in the monolith.

Journal Article Type Article
Publication Date 2016
Journal Chemical communications
Print ISSN 1359-7345
Electronic ISSN 1364-548X
Publisher Royal Society of Chemistry
Peer Reviewed Peer Reviewed
Volume 52
Issue 45
Pages 7221-7224
APA6 Citation Tarn, M. D., Maneuski, D., Alexander, R., Brown, N. J., O’Shea, V., Pimlott, S. L., …Archibald, S. J. (2016). Positron detection in silica monoliths for miniaturised quality control of PET radiotracers. Chemical communications : Chem comm / the Royal Society of Chemistry, 52(45), 7221-7224. https://doi.org/10.1039/c6cc00660d
DOI https://doi.org/10.1039/c6cc00660d
Keywords PET radiotracers; Positron detection
Publisher URL http://pubs.rsc.org/en/content/articlelanding/2016/cc/c6cc00660d#!divAbstract
Copyright Statement This Open Access Article is licensed under a Creative Commons Attribution 3.0 Unported Licence

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Copyright Statement
This Open Access Article is licensed under a Creative Commons Attribution 3.0 Unported Licence



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