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Positron detection in silica monoliths for miniaturised quality control of PET radiotracers

Tarn, Mark D.; Maneuski, Dzmitry; Alexander, Richard; Brown, Nathaniel J.; O’Shea, Val; Pimlott, Sally L.; Pamme, Nicole; Archibald, Stephen J.


Mark D. Tarn

Dzmitry Maneuski

Richard Alexander

Nathaniel J. Brown

Val O’Shea

Sally L. Pimlott

Nicole Pamme


We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [⁶⁸Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control. The system achieved a far superior signal-to-noise ratio compared to conventional sodium iodide-based radio-HPLC detection and allowed real-time visualisation of positrons in the monolith.


Tarn, M. D., Maneuski, D., Alexander, R., Brown, N. J., O’Shea, V., Pimlott, S. L., …Archibald, S. J. (2016). Positron detection in silica monoliths for miniaturised quality control of PET radiotracers. Chemical communications : Chem comm / the Royal Society of Chemistry, 52(45), 7221-7224.

Journal Article Type Article
Acceptance Date Mar 16, 2016
Online Publication Date Mar 16, 2016
Publication Date 2016
Deposit Date Apr 11, 2016
Publicly Available Date Apr 11, 2016
Journal Chemical communications
Print ISSN 1359-7345
Electronic ISSN 1364-548X
Publisher Royal Society of Chemistry
Peer Reviewed Peer Reviewed
Volume 52
Issue 45
Pages 7221-7224
Keywords PET radiotracers; Positron detection
Public URL
Publisher URL!divAbstract


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Copyright Statement
This Open Access Article is licensed under a Creative Commons Attribution 3.0 Unported Licence

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