All Outputs (39)

A comparison of the knowledge and attitudes of concussion within higher and lower leagues of the community rugby union game (2022)
Journal Article
Oliver, B., Ashton, J., Welsby, G., & Simpson, A. (2022). A comparison of the knowledge and attitudes of concussion within higher and lower leagues of the community rugby union game. Physical Therapy in Sport, 58, 151-159. https://doi.org/10.1016/j.ptsp.2022.10.009

Objectives: The Rugby Football Union (RFU) HEADCASE initiative aims to educate coaches, referees, and players on concussion. Concussion in community rugby is under-reported. Therefore, players can play a role in concussion safety if they have adequat... Read More about A comparison of the knowledge and attitudes of concussion within higher and lower leagues of the community rugby union game.

Errors of measurement for blood parameters, physiological and performance measures after the decay of short-term heat acclimation (2022)
Journal Article
Garrett, A. T., Rehrer, N. J., Patterson, M. J., Simpson, A. J., & Cotter, J. D. (2022). Errors of measurement for blood parameters, physiological and performance measures after the decay of short-term heat acclimation. Journal of Human Performance in Extreme Environments, 17(1), Article 5. https://doi.org/10.7771/2327-2937.1140

Introduction: It is important to determine the accuracy of measurements relative to potential treatment effects, with time intervals between tests. Purpose: The aim of this study was to assess the error of measurement for blood parameters, physiologi... Read More about Errors of measurement for blood parameters, physiological and performance measures after the decay of short-term heat acclimation.

Tele-rehabilitation for patients who have been hospitalised with Covid-19: a mixed-methods feasibility trial protocol (2022)
Journal Article
Hyde, L., Simpson, A. J., Nettleton, M., Shepherdson, J., Killingback, C., Marshall, P., …Green, A. (2022). Tele-rehabilitation for patients who have been hospitalised with Covid-19: a mixed-methods feasibility trial protocol. Physical Therapy Reviews, https://doi.org/10.1080/10833196.2022.2028963

Background: Tele-rehabilitation has been proposed as a post-hospitalisation rehabilitation pathway for Covid-19 survivors, however patients’ willingness and ability to engage with this online intervention remains unknown. Objectives: The aim of this... Read More about Tele-rehabilitation for patients who have been hospitalised with Covid-19: a mixed-methods feasibility trial protocol.

Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort (2021)
Journal Article
Ahmed, H., Auffray, C., Bakke, P., Bush, A., Baribaud, F., Bates, S., Bel, E. H., Bigler, J., Bisgaard, H., Boedigheimer, M. J., Bønnelykke, K., Brandsma, J., Brinkman, P., Bucchioni, E., Burg, D., Caruso, M., Chaiboonchoe, A., Chanez, P., Chung, F. K., Compton, C. H., …Study Group, U.-B. (2021). Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort. Chest, 160(1), 53-64. https://doi.org/10.1016/j.chest.2021.02.023

Background: Although estimates of suboptimal adherence to oral corticosteroids in asthma range from 30% to 50%, no ideal method for measurement exists; the impact of poor adherence in severe asthma is likely to be particularly high. Research Question... Read More about Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort.

Triggers of Breathlessness in Inducible Laryngeal Obstruction and Asthma (2020)
Journal Article
Haines, J., Chua, S. H., Smith, J., Slinger, C., Simpson, A. J., & Fowler, S. J. (2020). Triggers of Breathlessness in Inducible Laryngeal Obstruction and Asthma. Clinical and Experimental Allergy, 50(11), 1230-1237. https://doi.org/10.1111/cea.13715

Background
Inducible laryngeal obstruction (ILO) is often misdiagnosed as, or may coexist with, asthma. Identifying differences in triggering factors may assist clinicians to differentiate between the two conditions, and could give mechanistic insig... Read More about Triggers of Breathlessness in Inducible Laryngeal Obstruction and Asthma.

Epidemiology and pathophysiology of exercise-induced bronchoconstriction in athletes (2020)
Book Chapter
Kippelen, P., & Simpson, A. (2020). Epidemiology and pathophysiology of exercise-induced bronchoconstriction in athletes. In J. W. Dickinson, & J. H. Hull (Eds.), Complete Guide to Respiratory Care in Athletes. Routledge. https://doi.org/10.4324/9780429492341

Exercise-induced bronchoconstriction: a survey of diagnostic practice in secondary care across the United Kingdom (2020)
Journal Article
Simpson, A. J., Drake, S., & Fowler, S. (2020). Exercise-induced bronchoconstriction: a survey of diagnostic practice in secondary care across the United Kingdom. Allergy, 75(8), 2130-2132. https://doi.org/10.1111/all.14305

Effectiveness of myAirCoach: A mHealth Self-Management System in Asthma (2020)
Journal Article
Khusial, R. J., Honkoop, P. J., Usmani, O., Soares, M., Simpson, A., Biddiscombe, M., Meah, S., Bonini, M., Lalas, A., Polychronidou, E., Koopmans, J. G., Moustakas, K., Snoeck-Stroband, J. B., Ortmann, S., Votis, K., Tzovaras, D., Chung, K. F., Fowler, S., & Sont, J. K. (2020). Effectiveness of myAirCoach: A mHealth Self-Management System in Asthma. The journal of allergy and clinical immunology. In practice, 8(6), 1972-1979.e8. https://doi.org/10.1016/j.jaip.2020.02.018

Background: Self-management programs have beneficial effects on asthma control, but their implementation in clinical practice is poor. Mobile health (mHealth) could play an important role in enhancing self-management. Objective: To assess the clinica... Read More about Effectiveness of myAirCoach: A mHealth Self-Management System in Asthma.

Effect of creatine supplementation on the airways of youth elite soccer players (2019)
Journal Article
Simpson, A. J., Horne, S., Sharp, P., Sharps, R., & Kippelen, P. (2019). Effect of creatine supplementation on the airways of youth elite soccer players. Medicine and Science in Sports and Exercise, 51(8), 1582-1590. https://doi.org/10.1249/MSS.0000000000001979

Introduction Owing to its well-established ergogenic potential, creatine is a highly popular food supplement in sports. As an oral supplement, creatine is considered safe and ethical. However, no data exist on the safety of creatine on lung function... Read More about Effect of creatine supplementation on the airways of youth elite soccer players.

Treatable traits in the European U-BIOPRED adult asthma cohorts (2018)
Journal Article
Simpson, A. J., Hekking, P. P., Shaw, D. E., Fleming, L. J., Roberts, G., Riley, J. H., Bates, S., Sousa, A. R., Bansal, A. T., Pandis, I., Sun, K., Bakke, P. S., Caruso, M., Dahlén, B., Dahlén, S. E., Horvath, I., Krug, N., Montuschi, P., Sandstrom, T., Singer, F., …the U-BIOPRED Study Group. (2019). Treatable traits in the European U-BIOPRED adult asthma cohorts. Allergy, 74(2), 406-411. https://doi.org/10.1111/all.13629

Letter to the editor

Reclassification of Bronchodilator Reversibility in the U-BIOPRED Adult Asthma Cohort Using z Scores (2018)
Journal Article
Simpson, A. J., & Fowler, S. J. (2018). Reclassification of Bronchodilator Reversibility in the U-BIOPRED Adult Asthma Cohort Using z Scores. Chest, 153(4), 1070-1072. https://doi.org/10.1016/j.chest.2017.10.051

Effect of spirometry on intra-thoracic pressures (2018)
Journal Article
Tiller, N. B., & Simpson, A. J. (2018). Effect of spirometry on intra-thoracic pressures. BMC research notes, 11(1), Article 110. https://doi.org/10.1186/s13104-018-3217-9

Objective

Due to the high intra-thoracic pressures associated with forced vital capacity manoeuvres, spirometry is contraindicated for vulnerable patients. However, the typical pressure response to spirometry has not been reported. Eight healthy, re... Read More about Effect of spirometry on intra-thoracic pressures.

Assessing machine learning algorithms for self-management of asthma (2017)
Presentation / Conference Contribution
Kocsis, O., Arvanitis, G., Lalos, A., Moustakas, K., Sont, J. K., Honkoop, P. J., Chung, K. F., Bonini, M., Usmani, O. S., Fowler, S., & Simpson, A. (2017, June). Assessing machine learning algorithms for self-management of asthma. Presented at The 6th IEEE International Conference on E-Health and Bioengineering - EHB 2017, Sinaia, Romania

© 2017 IEEE. Control and monitoring of asthma progress is highly important for patient's quality of life and healthcare management. Emerging tools for self-management of various chronic diseases have the potential to support personalized patient guid... Read More about Assessing machine learning algorithms for self-management of asthma.

Exercise-induced dehydration alters pulmonary function but does not modify airway responsiveness to dry air in athletes with mild asthma (2017)
Journal Article
Simpson, A. J., Romer, L. M., & Kippelen, P. (2017). Exercise-induced dehydration alters pulmonary function but does not modify airway responsiveness to dry air in athletes with mild asthma. Journal of Applied Physiology, 122(5), 1329-1335. https://doi.org/10.1152/japplphysiol.01114.2016

Local airway water loss is the main physiological trigger for exercise-induced bronchoconstriction (EIB). Our aim was to investigate the effects of whole body water loss on airway responsiveness and pulmonary function in athletes with mild asthma and... Read More about Exercise-induced dehydration alters pulmonary function but does not modify airway responsiveness to dry air in athletes with mild asthma.

Perspectives of patients and healthcare professionals on mHealth for asthma self-management (2017)
Journal Article
Simpson, A. J., Honkoop, P. J., Kennington, E., Snoeck-Stroband, J., Smith, I., East, J., Coleman, C., Caress, A., Chung, K. F., Sont, J. K., Usmani, O., & Fowler, S. (2017). Perspectives of patients and healthcare professionals on mHealth for asthma self-management. European respiratory journal, 49(5), Article ARTN 1601966. https://doi.org/10.1183/13993003.01966-2016

Copyright ©ERS 2017. Mobile healthcare (mHealth) has the potential to revolutionise the self-management of long-term medical conditions such as asthma. A user-centred design is integral if mHealth is to be embraced by patients and healthcare professi... Read More about Perspectives of patients and healthcare professionals on mHealth for asthma self-management.

MyAirCoach: The use of home-monitoring and mHealth systems to predict deterioration in asthma control and the occurrence of asthma exacerbations; Study protocol of an observational study (2017)
Journal Article
Honkoop, P. J., Simpson, A., Bonini, M., Snoeck-Stroband, J. B., Meah, S., Chung, K. F., Usmani, O. S., Fowler, S., & Sont, J. K. (2017). MyAirCoach: The use of home-monitoring and mHealth systems to predict deterioration in asthma control and the occurrence of asthma exacerbations; Study protocol of an observational study. BMJ open, 7(1), Article ARTN e013935. https://doi.org/10.1136/bmjopen-2016-013935

© Published by the BMJ Publishing Group Limited. Introduction Asthma is a variable lung condition whereby patients experience periods of controlled and uncontrolled asthma symptoms. Patients who experience prolonged periods of uncontrolled asthma hav... Read More about MyAirCoach: The use of home-monitoring and mHealth systems to predict deterioration in asthma control and the occurrence of asthma exacerbations; Study protocol of an observational study.

A standard, single dose of inhaled terbutaline attenuates hyperpnea-induced bronchoconstriction and mast cell activation in athletes (2016)
Journal Article
Simpson, A. J., Bood, J. R., Anderson, S. D., Romer, L. M., Dahlén, B., Dahlén, S. E., & Kippelen, P. (2016). A standard, single dose of inhaled terbutaline attenuates hyperpnea-induced bronchoconstriction and mast cell activation in athletes. Journal of Applied Physiology, 120(9), 1011-1017. https://doi.org/10.1152/japplphysiol.00700.2015

Release of bronchoactive mediators from mast cells during exercise hyperpnea is a key factor in the pathophysiology of exercise-induced bronchoconstriction (EIB). Our aim was to investigate the effect of a standard, single dose of an inhaled β 2 -adr... Read More about A standard, single dose of inhaled terbutaline attenuates hyperpnea-induced bronchoconstriction and mast cell activation in athletes.

Self-reported symptoms after induced and inhibited bronchoconstriction in athletes (2015)
Journal Article
Simpson, A. J., Romer, L. M., & Kippelen, P. (2015). Self-reported symptoms after induced and inhibited bronchoconstriction in athletes. Medicine and Science in Sports and Exercise, 47(10), 2005-2013. https://doi.org/10.1249/mss.0000000000000646

Purpose: A change in the perception of respiratory symptoms
after treatment with inhaled beta2 agonists is often used to aid diagnosis of exercise-induced bronchoconstriction (EIB). Our aim was to test the association between subjective ratings of r... Read More about Self-reported symptoms after induced and inhibited bronchoconstriction in athletes.

Effect of terbutaline on hyperpnoea-induced bronchoconstriction and urinary club cell protein 16 in athletes (2013)
Journal Article
Simpson, A. J., Simpson, A. J., Tufvesson, E., Tufvesson, E., Anderson, S. D., Anderson, S. D., Romer, L. M., Romer, L. M., Bjermer, L., Bjermer, L., Kippelen, P., & Kippelen, P. (2013). Effect of terbutaline on hyperpnoea-induced bronchoconstriction and urinary club cell protein 16 in athletes. Journal of Applied Physiology, 115(10), 1450-1456. https://doi.org/10.1152/japplphysiol.00716.2013

Repeated injury of the airway epithelium caused by hyperpnoea of poorly conditioned air has been proposed as a key factor in the pathogenesis of exercise-induced bronchoconstriction (EIB) in athletes. In animals, the short-acting β2-agonist terbutali... Read More about Effect of terbutaline on hyperpnoea-induced bronchoconstriction and urinary club cell protein 16 in athletes.