Induction of strain-transcending antibodies against group A PfEMP1 surface antigens from virulent malaria parasites
(2012)
Journal Article
Ghumra, A., Semblat, J. P., Ataide, R., Kifude, C., Adams, Y., Claessens, A., Anong, D. N., Bull, P. C., Fennell, C., Arman, M., Amambua-Ngwa, A., Walther, M., Conway, D. J., Kassambara, L., Doumbo, O. K., Raza, A., & Rowe, J. A. (2012). Induction of strain-transcending antibodies against group A PfEMP1 surface antigens from virulent malaria parasites. PLoS Pathogens, 8(4), Article e1002665. https://doi.org/10.1371/journal.ppat.1002665
Sequence diversity in pathogen antigens is an obstacle to the development of interventions against many infectious diseases. In malaria caused by Plasmodium falciparum, the PfEMP1 family of variant surface antigens encoded by var genes are adhesion m... Read More about Induction of strain-transcending antibodies against group A PfEMP1 surface antigens from virulent malaria parasites.