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Fast and low loss flexoelectro-optic liquid crystal phase modulator with a chiral nematic reflector (2019)
Journal Article
Wang, X., Fells, J. A. J., Yip, W. C., Ali, T., Lin, J., Welch, C., …Elston, S. J. (2019). Fast and low loss flexoelectro-optic liquid crystal phase modulator with a chiral nematic reflector. Scientific reports, 9, 1-8. https://doi.org/10.1038/s41598-019-42831-5

In this paper, we demonstrate a flexoelectro-optic liquid crystal phase-only device that uses a chiral nematic reflector to achieve full 2π phase modulation. This configuration is found to be very tolerant to imperfections in the chiral nematic refle... Read More

Bioimprint aided cell recognition and depletion of human leukemic HL60 cells from peripheral blood (2019)
Journal Article
Das, A. A., Medlock, J., Liang, H., Nees, D., Allsup, D. J., Madden, L. A., & Paunov, V. N. (in press). Bioimprint aided cell recognition and depletion of human leukemic HL60 cells from peripheral blood. Journal of materials chemistry B, Materials for biology and medicine /, https://doi.org/10.1039/c9tb00679f

We report a large scale preparation of bioimprints of layers of cultured human leukemic HL60 cells which can perform cell shape and size recognition from a mixture with peripheral blood mononuclear cells (PBMCs). We demonstrate that the bioimprint-ce... Read More

A method for determining average iron content of ferritin by measuring its optical dispersion (2019)
Journal Article
Gupta, R., Alamrani, N., Greenway, G. M., Pamme, N., & Goddard, N. (in press). A method for determining average iron content of ferritin by measuring its optical dispersion. Analytical chemistry, https://doi.org/10.1021/acs.analchem.9b01231

We report a method where the refractive index increments of an iron storage protein, ferritin, and apoferritin (ferritin minus iron) were measured over the wavelength range of 450 to 678 nm to determine the average iron content of the protein. The pr... Read More

Stabilization of Pd3−xIn1+x polymorphs with Pd-like crystal structure and their superior performance as catalysts for semi-hydrogenation of alkynes (2019)
Journal Article
Johnston, S. K., Bryant, T. A., Strong, J., Lazzarini, L., Ibhadon, A. O., & Francesconi, M. G. (in press). Stabilization of Pd3−xIn1+x polymorphs with Pd-like crystal structure and their superior performance as catalysts for semi-hydrogenation of alkynes. ChemCatChem, https://doi.org/10.1002/cctc.201900391

Selective hydrogenation (semi-hydrogenation) reactions of alkynes rely on Pd-based catalysts to provide the correct pathway to favour formation of double bonds and avoid full hydrogenation to single bonds. Here, we present the preparation and charact... Read More

Boosting the antimicrobial action of vancomycin formulated in shellac nanoparticles of dual-surface functionality (2019)
Journal Article
Al-Obaidy, S. S. M., Halbus, A. F., Greenway, G. M., & Paunov, V. N. (2019). Boosting the antimicrobial action of vancomycin formulated in shellac nanoparticles of dual-surface functionality. Journal of materials chemistry B, Materials for biology and medicine /, 7(19), 3119-3133. https://doi.org/10.1039/c8tb03102a

We report a strong amplification of the antimicrobial action of vancomycin (VCM) encapsulated in shellac nanoparticles (NPs) with dual surface functionalisation. These shellac nanocarriers for VCM were produced in two steps: (i) a pH drop from aqueou... Read More

Alkyl substituted 4-pyrrolidinopyridinium salts encapsulated in the cavity of cucurbit[10]uril (2019)
Journal Article
Xu, W., Liu, M., Escaño, M. C., Redshaw, C., Bian, B., Fan, Y., …Xiao, X. (in press). Alkyl substituted 4-pyrrolidinopyridinium salts encapsulated in the cavity of cucurbit[10]uril. New journal of chemistry = Nouveau journal de chimie, https://doi.org/10.1039/c9nj01089k

The interaction between cucuribit[10]uril (Q[10]) and a series of 4-pyrrolidinopyridinium salts bearing aliphatic substituents at the pyridinium nitrogen, namely 4-(C4H8N)C5H5NRBr, where R = Et (g1), n-butyl (g2), n-pentyl (g3), n-hexyl (g4), n-octyl... Read More

Synthesis, structures and Lewis‐Acid‐Induced isomerization of 8‐Methoxy[2.2]metaparacyclophanes and a DFT study (2019)
Journal Article
Islam, M. M., Feng, X., Rahman, S., Georghiou, P. E., Matsumoto, T., Tanaka, J., …Yamato, T. (2019). Synthesis, structures and Lewis‐Acid‐Induced isomerization of 8‐Methoxy[2.2]metaparacyclophanes and a DFT study. ChemistrySelect, 4(13), 3630-3635. https://doi.org/10.1002/slct.201900190

Methyl substituted 8‐methoxy[2.2]MPCPs 8 a–b were obtained via thiacyclophane and its oxidized products. Lewis acid‐catalyzed (AlCl3‐MeNO2) reactions of 5‐tert‐butyl‐8‐methoxy‐12,13,15,16‐tetramethyl[2.2]MPCP 8 b under various conditions led to trans... Read More

Hierarchically structured composites and porous materials from soft templates: fabrication and applications (2019)
Journal Article
Thompson, B. R., Horozov, T. S., Stoyanov, S. D., & Paunov, V. N. (in press). Hierarchically structured composites and porous materials from soft templates: fabrication and applications. Journal of materials chemistry. publ. by The Royal Society of Chemistry. A, Materials for energy and sustainability /, 7(14), 8030-8049. https://doi.org/10.1039/c8ta09750j

Recent experimental methods for fabrication of hierarchically porous and structured composites are reviewed. The main focus is on recent examples of how different soft templating materials, like emulsions, surfactant phases, breath figures, biologica... Read More

Pyrene-based aggregation-induced emission luminogens and their applications (2019)
Journal Article
Islam, M. M., Hu, Z., Wang, Q., Redshaw, C., & Feng, X. (2019). Pyrene-based aggregation-induced emission luminogens and their applications. Materials Chemistry Frontiers, https://doi.org/10.1039/c9qm00090a

"Unity is force"-Aesop. It is a common phenomenon that traditional chromophores exhibit high fluorescence in dilute solution yet luminescence is quenched at high concentrations or in the aggregate state, ie “aggregation-caused quenching” (ACQ). Tang... Read More

Cyclotrimerization of alkynes catalyzed by a self-supported cyclic tri-nuclear nickel(0) complex with α-diimine ligands (2019)
Journal Article
Shen, L., Zhao, Y., Luo, Q., Li, Q., Liu, B., Redshaw, C., …Yang, X. (2019). Cyclotrimerization of alkynes catalyzed by a self-supported cyclic tri-nuclear nickel(0) complex with α-diimine ligands. Dalton transactions : an international journal of inorganic chemistry / RSoC, https://doi.org/10.1039/c9dt00819e

A cyclic tri-nuclear α-diimine nickel(0) complex [{Ni(μ-LMe-2,4)}3] (2) was synthesized from a “pre-organized”, trimerized trigonal LNiBr2-type precursor [Ni3(μ2-Br)3(μ3-Br)2(LMe-2,4)3]·Br (1; LMe-2,4 = [(2,4-Me2C6H3)NC(Me)]2). In complex 2, the α-di... Read More

Strongly Enhanced Antibacterial Action of Copper Oxide Nanoparticles with Boronic Acid Surface Functionality (2019)
Journal Article
Halbus, A. F., Horozov, T. S., & Paunov, V. N. (in press). Strongly Enhanced Antibacterial Action of Copper Oxide Nanoparticles with Boronic Acid Surface Functionality. ACS applied materials & interfaces, https://doi.org/10.1021/acsami.8b21862

Copper oxide nanoparticles (CuONPs) have been widely recognized as good antimicrobial agents but are heavily regulated due to environmental concerns of their postuse. In this work, we have developed and tested a novel type of formulation for copper o... Read More

N-cinnamoylanthranilates as human TRPA1 modulators: Structure-activity relationships and channel binding sites (2019)
Journal Article
Chandrabalan, A., McPhillie, M. J., Morice, A. H., Boa, A. N., & Sadofsky, L. R. (2019). N-cinnamoylanthranilates as human TRPA1 modulators: Structure-activity relationships and channel binding sites. European Journal of Medicinal Chemistry, doi:10.1016/j.ejmech.2019.02.074

The transient receptor potential ankyrin 1 (TRPA1) channel is a non-selective cation channel, which detects noxious stimuli leading to pain, itch and cough. However, the mechanism(s) of channel modulation by many of the known, non-reactive modulators... Read More

Robust measurement of flexoelectro-optic switching with different surface alignments (2019)
Journal Article
Sandford O’Neill, J. J., Fells, J. A. J., Welch, C., Mehl, G., Yip, W. C., Wilkinson, T. D., …Morris, S. M. (2019). Robust measurement of flexoelectro-optic switching with different surface alignments. Journal of applied physics, 125(9), doi:10.1063/1.5086241

The alignment of chiral nematic liquid crystals in the so-called uniform lying helix geometry allows for the observation and exploitation of the flexoelectro-optic effect. However, high-quality uniform lying helix alignment is difficult to achieve re... Read More

Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads (2019)
Journal Article
Hubin, T. J., Walker, A. N., Davilla, D. J., Carder Freeman, T. R. N., Epley, B. M., Hasley, T. R., …Khan, M. O. F. (2019). Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads. Polyhedron, 163, 42-53. https://doi.org/10.1016/j.poly.2019.02.027

© 2019 A total of 44 bis-aryl-monocyclic polyamines, monoaryl-monocyclic polyamines and their transition metal complexes were prepared, chemically characterized, and screened in vitro against the Leishmania donovani promastigotes, axenic amastigotes... Read More

The inhibitory subunit of cardiac troponin (cTnI) is modified by arginine methylation in the human heart (2019)
Journal Article
Onwuli, D. O., Samuel, S., Sfyri, P., Welham, K., Goddard, M., Abu-Omar, Y., …Beltran-Alvarez, P. (2019). The inhibitory subunit of cardiac troponin (cTnI) is modified by arginine methylation in the human heart. International journal of cardiology, 282, 76-80. https://doi.org/10.1016/j.ijcard.2019.01.102

Background The inhibitory subunit of cardiac troponin (cTnI) is a gold standard cardiac biomarker and also an essential protein in cardiomyocyte excitation-contraction coupling. The interactions of cTnI with other proteins are fine-tuned by post-tra... Read More

1H NMR study of molecular order and dynamics in CBC9CB Liquid Crystal (2019)
Journal Article
Aluculesei, A., Cachitas, H., Carvalho, J., Vaca Chavez, F., Figueirinhas, J. L., Sebastião, P. J., …Mehl, G. H. (2019). 1H NMR study of molecular order and dynamics in CBC9CB Liquid Crystal. Physical chemistry chemical physics : PCCP, doi:10.1039/c8cp06868b

Molecular order and dynamics of the CB-C9-CB liquid crystalline dimer exhibiting the nematic (N) and the twist bend nematic (Ntb) phases were investigated by proton NMR spectroscopy, using fields of 0.78T and 7.04T, and relaxometry. The first relaxom... Read More

Acetate as a model for aspartate-based CXCR4 chemokine receptor binding of cobalt and nickel complexes of cross-bridged tetraazamacrocycles (2019)
Journal Article
Cain, A. N., Carder Freeman, T. N., Roewe, K. D., Cockriel, D. L., Hasley, T. R., Maples, R. D., …Hubin, T. J. (2019). Acetate as a model for aspartate-based CXCR4 chemokine receptor binding of cobalt and nickel complexes of cross-bridged tetraazamacrocycles. Dalton transactions : an international journal of inorganic chemistry / RSoC, 48(8), 2785-2801. https://doi.org/10.1039/c8dt04728f

A number of disease states including WHIM syndrome, HIV infection and cancer have been linked to the chemokine receptor CXCR4. High-affinity CXCR4 antagonist transition metal complexes of configurationally restricted bis-tetraazamacrocyclic ligands h... Read More

Stereolithographic 3D printing of extrinsically self-healing composites (2019)
Journal Article
Sanders, P., Young, A. J., Qin, Y., Fancey, K. S., Reithofer, M. R., Guillet-Nicolas, R., …Chin, J. M. (2019). Stereolithographic 3D printing of extrinsically self-healing composites. Scientific reports, 9(1), doi:10.1038/s41598-018-36828-9

We demonstrate for the first time the direct stereolithographic 3D printing of an extrinsically self-healing composite, comprised of commercial photocurable resin modified with anisole and PMMA-filled microcapsules. The composites demonstrate solvent... Read More

Pickering emulsion-enhanced interfacial biocatalysis: tailored alginate microparticles act as particulate emulsifier and enzyme carrier (2019)
Journal Article
Yang, X., Wang, Y., Bai, R., Ma, H., Wang, W., Sun, H., …Meng, T. (in press). Pickering emulsion-enhanced interfacial biocatalysis: tailored alginate microparticles act as particulate emulsifier and enzyme carrier. Green chemistry : an international journal and green chemistry resource : GC, doi:10.1039/C8GC03573C

A robust Pickering emulsion stabilized by lipase-immobilized alginate gel microparticles with a coating of silanized titania nanoparticles is developed for biphasic biocatalysis. The good recyclability and high stability of the proposed interfacial c... Read More

Proton and Deuterium NMR study of the CBC9CB Dimer System (2019)
Journal Article
Carvalho, J., Cruz, C., Figueirinhas, J. L., Tamba, M., Kohlmeier, A., & Mehl, G. H. (in press). Proton and Deuterium NMR study of the CBC9CB Dimer System. Journal of Physical Chemistry B, doi:10.1021/acs.jpcb.8b11526

Using proton and deuterium NMR spectroscopy , this work provides a description of the molecular order of the mesogenic grops in both the Ntb and the classical nematic phase (N), of the liquid crystal dimer CB-C9CB. The proton NMR data were collected... Read More