All Outputs (84)

A cross sectional pilot study utilising STrain Analysis and Mapping of the Plantar Surface (STAMPS) to measure plantar load characteristics within a healthy population (2024)
Journal Article
Jones, A. D., Crossland, S., Nixon, J. E., Siddle, H. J., Culmer, P. R., & Russell, D. A. (2024). A cross sectional pilot study utilising STrain Analysis and Mapping of the Plantar Surface (STAMPS) to measure plantar load characteristics within a healthy population. Gait and Posture, 113, 246-251. https://doi.org/10.1016/j.gaitpost.2024.06.018

Background: No in-shoe systems, measuring both components of plantar load (plantar pressure and shear stress) are available for use in patients with diabetes. The STAMPS (STrain Analysis and Mapping of the Plantar Surface) system utilises digital ima... Read More about A cross sectional pilot study utilising STrain Analysis and Mapping of the Plantar Surface (STAMPS) to measure plantar load characteristics within a healthy population.

Incorporating pathological gait into patient-specific finite element models of the haemophilic ankle (2024)
Journal Article
Talbott, H. G., Wilkins, R. A., Brockett, C. L., & Mengoni, M. (2024). Incorporating pathological gait into patient-specific finite element models of the haemophilic ankle. Biomechanics and Modeling in Mechanobiology, https://doi.org/10.1007/s10237-024-01857-z

Haemarthrosis is an inherent clinical feature of haemophilia, a disease characterised by an absence or reduction in clotting proteins. Patients with severe haemophilia experience joint bleeding leading to blood-induced ankle arthropathy (haemarthropa... Read More about Incorporating pathological gait into patient-specific finite element models of the haemophilic ankle.

In Silico and invitro modelling of chronic wounds to improve our understanding of wound biomechanics and to test novel medical devices (2024)
Thesis
Hendon, A. C. In Silico and invitro modelling of chronic wounds to improve our understanding of wound biomechanics and to test novel medical devices. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4703110

Negative pressure wound therapy (NPWT) is a widely used system that aids the healing of chronic wounds through the application of sub-atmospheric pressure. The effectiveness of this method is widely recognised, however the mechanisms behind this are... Read More about In Silico and invitro modelling of chronic wounds to improve our understanding of wound biomechanics and to test novel medical devices.

Predicting the Fracture Toughness of Human Cancellous Bone in Fractured Neck of Femur Patients Using Bone Volume and Micro-Architecture (2024)
Journal Article
Adams, G. J., Cook, R. B., Gibson, M., & Zioupos, P. (2024). Predicting the Fracture Toughness of Human Cancellous Bone in Fractured Neck of Femur Patients Using Bone Volume and Micro-Architecture. Life, 14(4), Article 467. https://doi.org/10.3390/life14040467

The current protocol used to determine if an individual is osteoporotic relies on assessment of the individual’s bone mineral density (BMD), which allows clinicians to judge the condition of a patient with respect to their peers. This, in essence, ev... Read More about Predicting the Fracture Toughness of Human Cancellous Bone in Fractured Neck of Femur Patients Using Bone Volume and Micro-Architecture.

Parametrization of the Calcaneus and Medial Cuneiform to Aid Potential Advancements in Flatfoot Surgery (2024)
Journal Article
Cai, Y., Pascoletti, G., Zioupos, P., Budair, B., Zanetti, E. M., Ringrose, T. J., & Junaid, S. (2024). Parametrization of the Calcaneus and Medial Cuneiform to Aid Potential Advancements in Flatfoot Surgery. Life, 14(3), Article 328. https://doi.org/10.3390/life14030328

Introduction: Flatfoot is a condition commonly seen in children; however, there is general disagreement over its incidence, characterization and correction. Painful flatfoot accompanied with musculoskeletal and soft tissue problems requires surgery t... Read More about Parametrization of the Calcaneus and Medial Cuneiform to Aid Potential Advancements in Flatfoot Surgery.

M3D-BIO - Microfluidics-Enabled 3D Printing for Biofabrication (2023)
Presentation / Conference Contribution
Moetazedian, A., Candeo, A., Bassi, A., Cox, L. R., Grover, L. M., & Poologasundarampillai, G. (2023, June). M3D-BIO - Microfluidics-Enabled 3D Printing for Biofabrication. Presented at 2nd International Conference on Medical Devices: Materials, Mechanics and Manufacturing (ICMD3M 2023), Corfu, Greece

Microfluidics market is the fastest growing research area in the world, and they have shown much promise in biofabrication and 3D bioprinting of tissues and organs. However, microfluidics is conventionally produced using drawn-out and expensive litho... Read More about M3D-BIO - Microfluidics-Enabled 3D Printing for Biofabrication.

Bioartificial scaffolds fabrication and their use for in vitro testing of wound healing devices (2023)
Thesis
Mandolini, N. Bioartificial scaffolds fabrication and their use for in vitro testing of wound healing devices. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4386661

In the last decades Negative Pressure Wound Therapy (NPWT) has shown its efficacy in wound healing, applying continuous or intermittent subatmospheric pressure to the wound surface by means of dressing systems. While there is general consen... Read More about Bioartificial scaffolds fabrication and their use for in vitro testing of wound healing devices.

Microfluidic-based 3D bioprinting to fabricate blood vasculature (2023)
Presentation / Conference Contribution
Moetazedian, A., Cox, L., Grover, L., & Poologasundarampillai, G. (2022, June). Microfluidic-based 3D bioprinting to fabricate blood vasculature. Presented at UK Society for Biomaterials 22nd Annual Conference (UKSB 2022), University of Sheffield

Introduction:
The most substantial healthcare challenge facing the UK is the inevitable transition towards ageing population. Organ transplantation as the gold-standard treatment has saved many lives and millions of pounds for the NHS; however, ever... Read More about Microfluidic-based 3D bioprinting to fabricate blood vasculature.

The relationship between subchondral bone cysts and cartilage health in the Tibiotalar joint: A finite element analysis (2022)
Journal Article
Talbott, H. G., Wilkins, R. A., Redmond, A. C., Brockett, C. L., & Mengoni, M. (2022). The relationship between subchondral bone cysts and cartilage health in the Tibiotalar joint: A finite element analysis. Clinical biomechanics, 99, Article 105745. https://doi.org/10.1016/j.clinbiomech.2022.105745

Background: Subchondral bone cysts are a common presentation in ankle haemarthropathy. The relationship with ankle joint health has however not previously been investigated. The aim of this study was to assess the influence of subchondral bone cysts... Read More about The relationship between subchondral bone cysts and cartilage health in the Tibiotalar joint: A finite element analysis.

CONVEX microfluidic devices: a new microscale agile manufacturing pipeline for material extrusion additive manufacturing (2022)
Preprint / Working Paper
Moetazedian, A., Nasrollahi, V., Candeo, A., Cox, L., Grover, L., & Poologasundarampillai, G. CONVEX microfluidic devices: a new microscale agile manufacturing pipeline for material extrusion additive manufacturing

This study is the first to report the fabrication of complex microfluidic devices based on CONtinuously Varied EXtrusion (CONVEX) of extruded filament in material extrusion additive manufacturing (MEAM). A range of complex geometries and channel widt... Read More about CONVEX microfluidic devices: a new microscale agile manufacturing pipeline for material extrusion additive manufacturing.

Study of the composition, processing and microstructure relationship of light alloys (2022)
Thesis
Sumayli, A. I. Study of the composition, processing and microstructure relationship of light alloys. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4508161

This research consists of two main parts. The first part concerns the study of the effect of pulse electromagnetic fields on the microstructural evolution and the hardness of an Al-20%Si alloy. A pulse magnetic field apparatus is used to produce diff... Read More about Study of the composition, processing and microstructure relationship of light alloys.

Biomechanical evaluation of the unilateral crossbite on the asymmetrical development of the craniofacial complex. A mechano-morphological approach (2022)
Journal Article
Ortún-Terrazas, J., Fagan, M. J., Cegoñino, J., Illipronti-Filho, E., & del Palomar, A. P. (2022). Biomechanical evaluation of the unilateral crossbite on the asymmetrical development of the craniofacial complex. A mechano-morphological approach. Computer Methods and Programs in Biomedicine, 217, Article 106703. https://doi.org/10.1016/j.cmpb.2022.106703

Background and Objective: The occlusion effect on the craniofacial development is a controversial topic that has attracted the interest of many researchers but that remains unclear, mainly due to the difficulties on measure its mechanical response ex... Read More about Biomechanical evaluation of the unilateral crossbite on the asymmetrical development of the craniofacial complex. A mechano-morphological approach.

Back to the bones: do muscle area assessment techniques predict functional evolution across a macroevolutionary radiation? (2021)
Journal Article
Bates, K. T., Wang, L., Dempsey, M., Broyde, S., Fagan, M. J., & Cox, P. G. (2021). Back to the bones: do muscle area assessment techniques predict functional evolution across a macroevolutionary radiation?. Interface, 18(180), Article 20210324. https://doi.org/10.1098/rsif.2021.0324

Measures of attachment or accommodation area on the skeleton are a popular means of rapidly generating estimates of muscle proportions and functional performance for use in large-scale macroevolutionary studies. Herein, we provide the first evaluatio... Read More about Back to the bones: do muscle area assessment techniques predict functional evolution across a macroevolutionary radiation?.

Morphological variation of the hemophilic talus (2021)
Journal Article
Talbott, H. G., Wilkins, R. A., Redmond, A. C., Brockett, C. L., & Mengoni, M. (2021). Morphological variation of the hemophilic talus. Clinical Anatomy, 34(6), 941-947. https://doi.org/10.1002/ca.23757

Flattening of the trochlear tali is clinically observed as structural and functional changes advance in patients with hemarthropathy of the ankle. However, the degree of this flattening has not yet been quantified, and distribution of the morphologic... Read More about Morphological variation of the hemophilic talus.

Correction to: Evolutionary biomechanics: Hard tissues and soft evidence? (Proc. R. Soc. B (2021) 288 (20202809) DOI: 10.1098/rspb.2020.2809) (2021)
Journal Article
Broyde, S., Dempsey, M., Wang, L., Cox, P. G., Fagan, M., & Bates, K. T. (2021). Correction to: Evolutionary biomechanics: Hard tissues and soft evidence? (Proc. R. Soc. B (2021) 288 (20202809) DOI: 10.1098/rspb.2020.2809). Proceedings of the Royal Society B: Biological Sciences, 288(1950), Article 20202809. https://doi.org/10.1098/rspb.2021.0831

Further analysis of our finite element (FE) models, as part of ongoing work, has revealed a systematic error running through all 30 models in our original analysis. In all 30 FE models, the force magnitudes applied to represent maximum isometric cont... Read More about Correction to: Evolutionary biomechanics: Hard tissues and soft evidence? (Proc. R. Soc. B (2021) 288 (20202809) DOI: 10.1098/rspb.2020.2809).

Evolutionary biomechanics: hard tissues and soft evidence? (2021)
Journal Article
Broyde, S., Dempsey, M., Wang, L., Cox, P. G., Fagan, M., & Bates, K. T. (2021). Evolutionary biomechanics: hard tissues and soft evidence?. Proceedings of the Royal Society B: Biological Sciences, 288(1945), Article 20202809. https://doi.org/10.1098/rspb.2020.2809

Biomechanical modelling is a powerful tool for quantifying the evolution of functional performance in extinct animals to understand key anatomical innovations and selective pressures driving major evolutionary radiations. However, the fossil record i... Read More about Evolutionary biomechanics: hard tissues and soft evidence?.

Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading (2020)
Presentation / Conference Contribution
Moetazedian, A., Gleadall, A., Mele, E., & Silberschmidt, V. V. (2020, June). Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading. Presented at 1st Virtual European Conference on Fracture, Online

With a general cautious attitude regarding the anisotropic properties of upright 3D-printed parts, there is a lack of fundamental understanding of behavior of 3D-printed polymers under cyclic loading condition, which is more representative of real-li... Read More about Damage in extrusion additive manufactured parts: Effect of environment and cyclic loading.

Viscoelastically active sutures – A stitch in time? (2020)
Journal Article
France, L. A., & Fancey, K. S. (2021). Viscoelastically active sutures – A stitch in time?. Materials Science and Engineering: C, 121, Article 111695. https://doi.org/10.1016/j.msec.2020.111695

We present results to show that a commercially available polypropylene suture filament (Ethicon Prolene), following annealing and tensile creep can, after creep load removal, release viscoelastically stored energy over a period of several weeks. Spec... Read More about Viscoelastically active sutures – A stitch in time?.

Mathematical modeling of canonical and non-canonical NF-κB pathways in TNF stimulation (2020)
Journal Article
Ji, B., Zhang, Y., Zhen, C., Fagan, M. J., & Yang, Q. (2020). Mathematical modeling of canonical and non-canonical NF-κB pathways in TNF stimulation. Computer Methods and Programs in Biomedicine, 196, Article 105677. https://doi.org/10.1016/j.cmpb.2020.105677

Background and objective: NF-κB can be activated by the canonical and non-canonical pathways. These two pathways interplay via the TRAF1|NIK complex after stimulation by TNF. However existing mathematical models of two pathways are inadequate. In thi... Read More about Mathematical modeling of canonical and non-canonical NF-κB pathways in TNF stimulation.

Multi-beat averaging reveals u waves are ubiquitous and standing tall at elevated heart rates following exercise (2020)
Journal Article
Al-Karadi, M. S., & Langley, P. (2020). Multi-beat averaging reveals u waves are ubiquitous and standing tall at elevated heart rates following exercise. Sensors, 20(14), 1-12. https://doi.org/10.3390/s20144029

The reporting of U wave abnormalities is clinically important, but the measurement of this small electrocardiographic (ECG) feature is extremely difficult, especially in challenging recording conditions, such as stress exercise, due to contaminating... Read More about Multi-beat averaging reveals u waves are ubiquitous and standing tall at elevated heart rates following exercise.