Projects (482)

North East Lincolnshire Creating Safer Communities Research Project Jul 1, 2016 - Aug 31, 2019
How does the provision of dedicated Signs of Safety (SOS) and Restorative Practice (RP) training, delivered in partnership with North East Lincolnshire Council, impact on students' learning and practice experiences?

Soy and testosterone: T01057 - Double placebo controlled parallel trial of soy phytoestrogens in patients with compensated hypogonadism Oct 1, 2009 - Apr 30, 2019

TSB Costs (Study 1, 2, 3 & 4): In vitro and in vivo assessment of polyphenol extracts on cardiovascular indices Jan 1, 2012 - Aug 1, 2016
Evidence suggests dietary plant polyphenols are associated with reducing indices of cardiovascular disease such as endothelial dysfunction, insulin resistance and hypertension. The key objectives of this translational research proposal are to study a... Read More about TSB Costs (Study 1, 2, 3 & 4): In vitro and in vivo assessment of polyphenol extracts on cardiovascular indices.

ISCHEMIA: Internation Study of Comparative Health Effectiveness with Medical and Invasive Approaches Apr 15, 2013 - Jun 30, 2019
Primary objective is to determine whether an invasive (INV) strategy of routine early cardiac catheterization with intent for optimal revascularization in addition to optimal medical therapy in patients with stable ischemic heart disease (SIHD) and a... Read More about ISCHEMIA: Internation Study of Comparative Health Effectiveness with Medical and Invasive Approaches.

Sandoz Ltd unfettered donation May 1, 2013 - Dec 31, 2017

Training scientists to develop and Image materials for Tissue Engineering and Regenerative Medicine (iTERM) Oct 1, 2013 - Sep 30, 2017
With an increasingly aging population, new treatment solutions for diseased, defective, or damaged tissues need to be developed. Although human donor material would be preferable for these purposes, this is often not available and often associated wi... Read More about Training scientists to develop and Image materials for Tissue Engineering and Regenerative Medicine (iTERM).

MIR: A double blind placebo-controlled randomised trial of the addition of the antidepressant mirtazapine Apr 1, 2013 - Apr 30, 2017
To investigate the effectiveness of combining mirtazapine with serotonin-noradrenaline reuptake inhibitor (SNRI) or selective serotonin reuptake inhibitor (SSRI) antidepressants for treatment resistant depression in primary care.

BreatheMOR: Morphine for the relief of breathlessness in stable chronic heart failure Oct 1, 2013 - Feb 28, 2019
Opioids have been used for centuries to relieve pain and other symptoms. A meta-analysis in 2002 of eight randomised controlled trials (RCTs) showed that opioids had a clinically relevant beneficial effect on dyspnoea in people with mainly chronic ob... Read More about BreatheMOR: Morphine for the relief of breathlessness in stable chronic heart failure.

NAT ILD: The adaption and validation of an assessment tool to identify the palliative care needs of people with irreversible idiopathic interstitial lung disease for use in every day clinical practice Jun 1, 2014 - Oct 31, 2016
To adapt and validate a needs assessment tool that is fit for purpose in every day clinical practice with regard to the identification of supportive and palliative needs of people with idiopathic pulmonary fibrosis (IPF), and triage those requiring r... Read More about NAT ILD: The adaption and validation of an assessment tool to identify the palliative care needs of people with irreversible idiopathic interstitial lung disease for use in every day clinical practice.

Research Care Plus Group Jan 1, 2016 - Dec 31, 2016
The NE Lincolnshire palliative care research team has been developing over the past year and has been successful in being involved in two portfolio adopted studies which have recruited to (one of which we recruited over 50% more than average). The te... Read More about Research Care Plus Group.

Speech Rehabilitation from Articulator Movement (SRAM) Jan 1, 2016 - Sep 30, 2018

In vitro analysis of thyroid cancer and it's response to radiotherapy May 22, 2015 - May 21, 2018

INTERACT: Integrated therapist and online CBT for depression in primary care Apr 1, 2016 - Nov 30, 2024
The overall aim of this programme is to improve outcomes for patients with depression in UK primary care. This will be achieved through a series of four linked work-streams that will firstly, develop an innovative approach to delivering cognitive beh... Read More about INTERACT: Integrated therapist and online CBT for depression in primary care.

A multisensory approach to itch Sep 1, 2015 - Aug 31, 2018
Many skin diseases are accompanied by chronic and sometimes intractable itch. As those suffering from it can testify, chronic itch impairs sleep, quality of life and mood, but treatment options are limited and often have unwanted side effects. From a... Read More about A multisensory approach to itch.

Development Of A Multimodal Bioimaging Platform For Detecting The Switch To Aggressive Prostate Cancer Oct 1, 2015 - Dec 31, 2018

Platelet cAMP signalling controls thrombosis through enhanced embolisation Oct 1, 2015 - Sep 30, 2018
The activation of protein kinase A (PKA) by prostacyclin inhibits platelet activation and therefore modulates arterial thrombosis. However, the role of PKA in controlling the stability of pre-existing thrombi is unclear. The stability of thrombi is r... Read More about Platelet cAMP signalling controls thrombosis through enhanced embolisation.

Coronin is a negative regulator of platelet spreading and thrombus formation Jul 1, 2016 - Jun 30, 2019
Platelets are a group of blood cells that become sticky and clump together to form Need guidance? blood clots, ensuring that we stop bleeding after injury. However, in some people platelets also form blood clots inside the blood vessels, which may le... Read More about Coronin is a negative regulator of platelet spreading and thrombus formation.

Health and Well Being of Female Football Players in the Preparation for Competition in the Heat Mar 1, 2016 - Nov 30, 2017

Sir Jules Thorn PhD Scholarship Programme 2016 Sep 1, 2016 - Aug 31, 2019
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lungs that affects about 15,000 people in the UK. There is no curative treatment and 5-year survival in IPF is worse than many cancers. Despite this, the pathogenesis of IPF... Read More about Sir Jules Thorn PhD Scholarship Programme 2016.

HIDDEN: Hospice Inpatient Deep vein thrombosis detection study May 27, 2016 - Dec 31, 2019
Between four and 20% of cancer patients will develop venous thromboembolism (VTE) during their illness but the true number is unknown as patients may be asymptomatic. Furthermore, we do not know whether apparently “silent” deep vein thromboses (DVTs)... Read More about HIDDEN: Hospice Inpatient Deep vein thrombosis detection study.